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MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors

ACS medicinal chemistry letters, 2015-06, Vol.6 (6), p.630-634

2015

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Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (22), p.9529-9533

2007

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Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)

Journal of medicinal chemistry, 2012-01, Vol.55 (1), p.197-208

2012

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Localization of the full-thickness cartilage lesions in medial and lateral unicompartmental knee osteoarthritis

Journal of orthopaedic research, 2009-10, Vol.27 (10), p.1339-1346

2009

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Effects of pre- and periconceptional undernutrition on arterial function in adult female sheep are vascular bed dependent

Experimental physiology, 2009-09, Vol.94 (9), p.1024-1033

2009

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Discovery and optimization of pyrazoline compounds as B-Raf inhibitors

Bioorganic & medicinal chemistry letters, 2010-08, Vol.20 (16), p.4800-4804

2010

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Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor

Nature chemical biology, 2017-11, Vol.13 (11), p.1164

2017

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Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer

Journal of medicinal chemistry, 2021-03, Vol.64 (5), p.2501-2520

2021

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Identification and structure–activity relationships of a new series of Melanocortin-4 receptor antagonists

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (8), p.2302-2305

2006

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Consumer-based brand equity and status-seeking motivation for a global versus local brand

Asia Pacific journal of marketing and logistics, 2011-06, Vol.23 (3), p.270-284

2011

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Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1‑Heteroaryl‑1H‑Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease

Journal of medicinal chemistry, 2022-12, Vol.65 (24), p.16801-16817

2022

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Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1 H -Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease

Journal of medicinal chemistry, 2022-12, Vol.65 (24), p.16801-16817

2022

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The approach of fused fissures with fissureless technique decreases the incidence of persistent air leak after lobectomy

European journal of cardio-thoracic surgery, 2007-02, Vol.31 (2), p.203-208

2007

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Design and Optimization of Potent and Orally Bioavailable Tetrahydronaphthalene Raf Inhibitors

Journal of medicinal chemistry, 2011-03, Vol.54 (6), p.1836-1846

2011

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Persistence of Residual Beta Cells and Islet Autoimmunity during Increasing Duration of Diabetes in NOD Mice and Experimental Approaches toward Reversing New-Onset Disease with Bioactive Peptides

Annals of the New York Academy of Sciences, 2008-12, Vol.1150 (1), p.171-176

2008

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Presence of residual beta cells and co-existing islet autoimmunity in the NOD mouse during longstanding diabetes: a combined histochemical and immunohistochemical study

Journal of Molecular Histology, 2008-02, Vol.39 (1), p.25-36

2008

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Fetal origins of coronary heart disease-implications for cardiothoracic surgery?

European journal of cardio-thoracic surgery, 2005-06, Vol.27 (6), p.1036-1042

2005

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International Federation for Emergency Medicine Consensus Statement: Sonography in hypotension and cardiac arrest (SHoC): An international consensus on the use of point of care ultrasound for undifferentiated hypotension and during cardiac arrest

Canadian journal of emergency medicine, 2017-11, Vol.19 (6), p.459-470

2017

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Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti

Science translational medicine, 2015-03, Vol.7 (279), p.279ra37

2015

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Mitochondria-Specific Aggregation-Induced Emission Luminogens for Selective Photodynamic Killing of Fungi and Efficacious Treatment of Keratitis

ACS nano, 2021-07, Vol.15 (7), p.12129-12139

2021

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Cancer cell discrimination and dynamic viability monitoring through wash-free bioimaging using AIEgens

Chemical science (Cambridge), 2020-07, Vol.11 (29), p.7676-7684

2020

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Multifunctional Supramolecular Assemblies with Aggregation-Induced Emission (AIE) for Cell Line Identification, Cell Contamination Evaluation, and Cancer Cell Discrimination

ACS nano, 2020-06, Vol.14 (6), p.7552-7563

2020

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One stone, three birds: one AIEgen with three colors for fast differentiation of three pathogens

Chemical science (Cambridge), 2020-04, Vol.11 (18), p.473-474

2020

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Highly Stable and Bright NIR-II AIE Dots for Intraoperative Identification of Ureter

ACS applied materials & interfaces, 2020-02, Vol.12 (7), p.8040-8049

2020

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Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors

MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors

Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood

Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)

Localization of the full-thickness cartilage lesions in medial and lateral unicompartmental knee osteoarthritis

Effects of pre- and periconceptional undernutrition on arterial function in adult female sheep are vascular bed dependent

Discovery and optimization of pyrazoline compounds as B-Raf inhibitors

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor

Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer

Identification and structure–activity relationships of a new series of Melanocortin-4 receptor antagonists

Consumer-based brand equity and status-seeking motivation for a global versus local brand

Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1‑Heteroaryl‑1H‑Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease

Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1 H -Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease

The approach of fused fissures with fissureless technique decreases the incidence of persistent air leak after lobectomy

Design and Optimization of Potent and Orally Bioavailable Tetrahydronaphthalene Raf Inhibitors

Persistence of Residual Beta Cells and Islet Autoimmunity during Increasing Duration of Diabetes in NOD Mice and Experimental Approaches toward Reversing New-Onset Disease with Bioactive Peptides

Presence of residual beta cells and co-existing islet autoimmunity in the NOD mouse during longstanding diabetes: a combined histochemical and immunohistochemical study

Fetal origins of coronary heart disease-implications for cardiothoracic surgery?

International Federation for Emergency Medicine Consensus Statement: Sonography in hypotension and cardiac arrest (SHoC): An international consensus on the use of point of care ultrasound for undifferentiated hypotension and during cardiac arrest

Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti

Mitochondria-Specific Aggregation-Induced Emission Luminogens for Selective Photodynamic Killing of Fungi and Efficacious Treatment of Keratitis

Cancer cell discrimination and dynamic viability monitoring through wash-free bioimaging using AIEgens

Multifunctional Supramolecular Assemblies with Aggregation-Induced Emission (AIE) for Cell Line Identification, Cell Contamination Evaluation, and Cancer Cell Discrimination

One stone, three birds: one AIEgen with three colors for fast differentiation of three pathogens

Highly Stable and Bright NIR-II AIE Dots for Intraoperative Identification of Ureter

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