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Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin‐mediated mitophagy

Journal of neurochemistry, 2016-01, Vol.136 (2), p.388-402

2016

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Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

Human molecular genetics, 2010-12, Vol.19 (24), p.4861-4870

2010

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Glucocerebrosidase 1 and leucine‐rich repeat kinase 2 in Parkinson disease and interplay between the two genes

Journal of neurochemistry, 2021-12, Vol.159 (5), p.826-839

2021

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PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy

The Journal of cell biology, 2016-04, Vol.213 (2), p.163-171

2016

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Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells

Brain (London, England : 1878), 2014-05, Vol.137 (5), p.1481-1495

2014

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Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

Scientific reports, 2016-08, Vol.6 (1), p.31380-31380, Article 31380

2016

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Insulin Resistance Promotes Parkinson's Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling

Cells (Basel, Switzerland), 2020-03, Vol.9 (3), p.740

2020

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Meclizine-induced enhanced glycolysis is neuroprotective in Parkinson disease cell models

Scientific reports, 2016-05, Vol.6 (1), p.25344-25344, Article 25344

2016

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Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage

Neurochemistry international, 2013-01, Vol.62 (1), p.1-7

2013

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G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization

Human molecular genetics, 2012-10, Vol.21 (19), p.4201-4213

2012

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Neuroprotection in Glaucoma: NAD+/NADH Redox State as a Potential Biomarker and Therapeutic Target

Cells (Basel, Switzerland), 2021-06, Vol.10 (6), p.1402

2021

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Relationship between alpha synuclein phosphorylation, proteasomal inhibition and cell death: relevance to Parkinson’s disease pathogenesis

Journal of neurochemistry, 2009-08, Vol.110 (3), p.1005-1013

2009

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The Role of Mitophagy in Glaucomatous Neurodegeneration

Cells (Basel, Switzerland), 2023-07, Vol.12 (15), p.1969

2023

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A Human Neural Crest Stem Cell-Derived Dopaminergic Neuronal Model Recapitulates Biochemical Abnormalities in GBA1 Mutation Carriers

Stem cell reports, 2017-03, Vol.8 (3), p.728-742

2017

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Resistance to the most common optic neuropathy is associated with systemic mitochondrial efficiency

Neurobiology of disease, 2015-10, Vol.82, p.78-85

2015

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The Cytomegalovirus protein pUL37×1 targets mitochondria to mediate neuroprotection

Scientific reports, 2016-08, Vol.6 (1), p.31373, Article 31373

2016

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Circulating anti‐retinal antibodies as immune markers in age‐related macular degeneration

Immunology, 2005-07, Vol.115 (3), p.422-430

2005

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The GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines

Human molecular genetics, 2023-02, Vol.32 (5), p.773-789

2023

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Recharging mitochondrial batteries in old eyes. Near infra-red increases ATP

Experimental eye research, 2014-05, Vol.122, p.50-53

2014

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GBA mutation promotes early mitochondrial dysfunction in 3D neurosphere models

Aging (Albany, NY.), 2019-11, Vol.11 (22), p.10338-10355

2019

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Protection against paraquat and A53T alpha-synuclein toxicity by cabergoline is partially mediated by dopamine receptors

Journal of the neurological sciences, 2009-03, Vol.278 (1), p.44-53

2009

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Mitochondrial dysfunction in glaucoma: understanding genetic influences

Mitochondrion, 2012-03, Vol.12 (2), p.202-212

2012

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α-Synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells: an in vitro proof of concept study

Brain communications, 2023-11, Vol.5 (6), p.fcad285-fcad285

2023

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Systemic PTEN-Akt1-mTOR pathway activity in patients with normal tension glaucoma and ocular hypertension: A case series

Mitochondrion, 2017-09, Vol.36, p.96-102

2017

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Molecular Dissection of the Architectural Transcription Factor HMGA2

Biochemistry (Easton), 2003-04, Vol.42 (15), p.4569-4577

2003

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Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin‐mediated mitophagy

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

Glucocerebrosidase 1 and leucine‐rich repeat kinase 2 in Parkinson disease and interplay between the two genes

PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy

Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells

Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

Insulin Resistance Promotes Parkinson's Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling

Meclizine-induced enhanced glycolysis is neuroprotective in Parkinson disease cell models

Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage

G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization

Neuroprotection in Glaucoma: NAD+/NADH Redox State as a Potential Biomarker and Therapeutic Target

Relationship between alpha synuclein phosphorylation, proteasomal inhibition and cell death: relevance to Parkinson’s disease pathogenesis

The Role of Mitophagy in Glaucomatous Neurodegeneration

A Human Neural Crest Stem Cell-Derived Dopaminergic Neuronal Model Recapitulates Biochemical Abnormalities in GBA1 Mutation Carriers

Resistance to the most common optic neuropathy is associated with systemic mitochondrial efficiency

The Cytomegalovirus protein pUL37×1 targets mitochondria to mediate neuroprotection

Circulating anti‐retinal antibodies as immune markers in age‐related macular degeneration

The GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines

Recharging mitochondrial batteries in old eyes. Near infra-red increases ATP

GBA mutation promotes early mitochondrial dysfunction in 3D neurosphere models

Protection against paraquat and A53T alpha-synuclein toxicity by cabergoline is partially mediated by dopamine receptors

Mitochondrial dysfunction in glaucoma: understanding genetic influences

α-Synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells: an in vitro proof of concept study

Systemic PTEN-Akt1-mTOR pathway activity in patients with normal tension glaucoma and ocular hypertension: A case series

Molecular Dissection of the Architectural Transcription Factor HMGA2

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