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HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon

PLoS pathogens, 2014-05, Vol.10 (5), p.e1004082-e1004082

2014

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Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus-Infected Donors to Noninfected Recipients: An Open-Label Nonrandomized Trial

Annals of internal medicine, 2018-04, Vol.168 (8), p.533

2018

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Allosteric coupling between Mn2+ and dsDNA controls the catalytic efficiency and fidelity of cGAS

Nucleic acids research, 2020-05, Vol.48 (8), p.4435

2020

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TGFβ1-Mediated SMAD3 Enhances PD-1 Expression on Antigen-Specific T Cells in Cancer

Cancer discovery, 2016-12, Vol.6 (12), p.1366-1381

2016

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Design principles for inflammasome inhibition by pyrin-only-proteins

eLife, 2024-01, Vol.13

2024

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Where do plasmacytoid dendritic cells find the energy?

Journal of leukocyte biology, 2021-02, Vol.109 (2), p.283-285

2021

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Lessons from the real world: HCV‐infected donor kidney transplantation as standard practice

American journal of transplantation, 2019-11, Vol.19 (11), p.2969-2970

2019

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Four-Week Direct-Acting Antiviral Prophylaxis for Kidney Transplantation From Hepatitis C-Viremic Donors to Hepatitis C-Negative Recipients: An Open-Label Nonrandomized Study

Annals of internal medicine, 2021-01, Vol.174 (1), p.137

2021

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Bypassing the bottleneck: intentional hepatitis C transmission with organ transplant

The Journal of clinical investigation, 2019-08, Vol.129 (8), p.3038-3040

2019

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Monocytes Activate Natural Killer Cells via Inflammasome-Induced Interleukin 18 in Response to Hepatitis C Virus Replication

Gastroenterology (New York, N.Y. 1943), 2014-07, Vol.147 (1), p.209-220.e3

2014

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Systemic Elevation of Proinflammatory Interleukin-18 in Human Immunodeficiency Virus (HIV)/Hepatitis C Virus (HCV) Coinfection Versus HIV or HCV Monoinfection

Clinical infectious diseases, 2017-03, Vol.64 (5), p.589-596

2017

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HIV-antibody complexes enhance production of type I interferon by plasmacytoid dendritic cells

The Journal of clinical investigation, 2017-12, Vol.127 (12), p.4352-4364

2017

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Assessment of inflammasome and type I IFN responses to DNA viruses and DNA PAMPS

Methods in enzymology, 2019, Vol.625, p.269-285

2019

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High Plasma Interleukin-18 Levels Mark the Acute Phase of Hepatitis C Virus Infection

The Journal of infectious diseases, 2011-12, Vol.204 (11), p.1730-1740

2011

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Systemic Elevation of Proinflammatory Interleukin 18 in HIV/HCV Coinfection versus HIV or HCV Monoinfection

Clinical infectious diseases, 2017-03, Vol.64 (5), p.589-596

2017

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Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses

JCI insight, 2022-06, Vol.7 (12)

2022

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Identification of crucial residues for the antibacterial activity of the proline‐rich peptide, pyrrhocoricin

European journal of biochemistry, 2002-09, Vol.269 (17), p.4226-4237

2002

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Coimmunization with an Optimized IL-15 Plasmid Results in Enhanced Function and Longevity of CD8 T Cells That Are Partially Independent of CD4 T Cell Help

The Journal of immunology (1950), 2005-07, Vol.175 (1), p.112-123

2005

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HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells

The Journal of immunology (1950), 2011-09, Vol.187 (6), p.2932-2943

2011

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Specific Immune Induction Following DNA-Based Immunization Through In Vivo Transfection and Activation of Macrophages/Antigen-Presenting Cells

The Journal of immunology (1950), 1998-06, Vol.160 (12), p.5707-5718

1998

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Host cell killing by the West Nile Virus NS2B–NS3 proteolytic complex: NS3 alone is sufficient to recruit caspase-8-based apoptotic pathway

Virology (New York, N.Y.), 2006-02, Vol.345 (1), p.56-72

2006

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WED-389 Pharmacokinetics and safety of the monoclonal antibody tobevibart (VIR-3434) administered as monotherapy or in combination with the small interfering RNA elebsiran (VIR-2218) in cirrhotic participants with mild hepatic impairment

Journal of hepatology, 2024-06, Vol.80, p.S816-S816

2024

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Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis

Nature biotechnology, 2000-09, Vol.18 (9), p.974-979

2000

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Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes

Nature biotechnology, 1997-07, Vol.15 (7), p.641-646

1997

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Co-immunization with plasmid IL-12 generates a strong T-cell memory response in mice

Vaccine, 2004-04, Vol.22 (13), p.1744-1750

2004

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HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon

Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus-Infected Donors to Noninfected Recipients: An Open-Label Nonrandomized Trial

Allosteric coupling between Mn2+ and dsDNA controls the catalytic efficiency and fidelity of cGAS

TGFβ1-Mediated SMAD3 Enhances PD-1 Expression on Antigen-Specific T Cells in Cancer

Design principles for inflammasome inhibition by pyrin-only-proteins

Where do plasmacytoid dendritic cells find the energy?

Lessons from the real world: HCV‐infected donor kidney transplantation as standard practice

Four-Week Direct-Acting Antiviral Prophylaxis for Kidney Transplantation From Hepatitis C-Viremic Donors to Hepatitis C-Negative Recipients: An Open-Label Nonrandomized Study

Bypassing the bottleneck: intentional hepatitis C transmission with organ transplant

Monocytes Activate Natural Killer Cells via Inflammasome-Induced Interleukin 18 in Response to Hepatitis C Virus Replication

Systemic Elevation of Proinflammatory Interleukin-18 in Human Immunodeficiency Virus (HIV)/Hepatitis C Virus (HCV) Coinfection Versus HIV or HCV Monoinfection

HIV-antibody complexes enhance production of type I interferon by plasmacytoid dendritic cells

Assessment of inflammasome and type I IFN responses to DNA viruses and DNA PAMPS

High Plasma Interleukin-18 Levels Mark the Acute Phase of Hepatitis C Virus Infection

Systemic Elevation of Proinflammatory Interleukin 18 in HIV/HCV Coinfection versus HIV or HCV Monoinfection

Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses

Identification of crucial residues for the antibacterial activity of the proline‐rich peptide, pyrrhocoricin

Coimmunization with an Optimized IL-15 Plasmid Results in Enhanced Function and Longevity of CD8 T Cells That Are Partially Independent of CD4 T Cell Help

HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells

Specific Immune Induction Following DNA-Based Immunization Through In Vivo Transfection and Activation of Macrophages/Antigen-Presenting Cells

Host cell killing by the West Nile Virus NS2B–NS3 proteolytic complex: NS3 alone is sufficient to recruit caspase-8-based apoptotic pathway

WED-389 Pharmacokinetics and safety of the monoclonal antibody tobevibart (VIR-3434) administered as monotherapy or in combination with the small interfering RNA elebsiran (VIR-2218) in cirrhotic participants with mild hepatic impairment

Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis

Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes

Co-immunization with plasmid IL-12 generates a strong T-cell memory response in mice

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