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Dynorphin--still an extraordinarily potent opioid peptide

Molecular pharmacology, 2013-04, Vol.83 (4), p.729-736

Chavkin, Charles

2013

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Kinase cascades and ligand-directed signaling at the kappa opioid receptor

Psychopharmacology, 2010-06, Vol.210 (2), p.137-147

2010

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Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor

Cellular signalling, 2017-04, Vol.32, p.59-65

2017

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Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system

Psychopharmacologia, 2008-09, Vol.200 (1), p.59-70

2008

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Regulation of Gonadotropin-Releasing Hormone Secretion by Kisspeptin/Dynorphin/Neurokinin B Neurons in the Arcuate Nucleus of the Mouse

The Journal of neuroscience, 2009-09, Vol.29 (38), p.11859-11866

2009

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Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons

The Journal of neuroscience, 2015-09, Vol.35 (37), p.12917-12931

2015

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Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive

Nature (London), 2012-10, Vol.490 (7420), p.402-406

2012

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Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (45), p.19168-19173

2009

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Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (25), p.11608-11613

2010

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Social Defeat Stress-Induced Behavioral Responses are Mediated by the Endogenous Kappa Opioid System

Neuropsychopharmacology (New York, N.Y.), 2006-06, Vol.31 (6), p.1241-1248

2006

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Stress produces aversion and potentiates cocaine reward by releasing endogenous dynorphins in the ventral striatum to locally stimulate serotonin reuptake

The Journal of neuroscience, 2012-12, Vol.32 (49), p.17582-17596

2012

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Partial Infraorbital Nerve Ligation as a Model of Trigeminal Nerve Injury in the Mouse: Behavioral, Neural, and Glial Reactions

The journal of pain, 2008-11, Vol.9 (11), p.1036-1048

2008

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The therapeutic potential of κ-opioids for treatment of pain and addiction

Neuropsychopharmacology (New York, N.Y.), 2011-01, Vol.36 (1), p.369-370

Chavkin, Charles

2011

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CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior

PloS one, 2009-12, Vol.4 (12), p.e8528-e8528

2009

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Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase

Nature communications, 2017-09, Vol.8 (1), p.743-14, Article 743

2017

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Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes

The Journal of biological chemistry, 2006-06, Vol.281 (26), p.18081-18089

2006

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Repeated Administration of Norbinaltorphimine Produces Cumulative Kappa Opioid Receptor Inactivation

Frontiers in pharmacology, 2019-02, Vol.10, p.88-88

2019

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Kappa-opioid antagonists as stress resilience medications for the treatment of alcohol use disorders

Neuropsychopharmacology (New York, N.Y.), 2018-08, Vol.43 (9), p.1803-1804

Chavkin, Charles

2018

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6.1 Molecular Pharmacology of Opioids: Chronic Stress and Developmental Exposures

Journal of the American Academy of Child and Adolescent Psychiatry, 2018-10, Vol.57 (10), p.S277-S278

Chavkin, Charles

2018

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Repeated swim stress induces kappa opioid-mediated activation of extracellular signal-regulated kinase 1/2

Neuroreport, 2008-09, Vol.19 (14), p.1417-1422

2008

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Disruption of Dopamine Neuron Activity Pattern Regulation through Selective Expression of a Human KCNN3 Mutation

Neuron (Cambridge, Mass.), 2013-11, Vol.80 (4), p.997-1009

2013

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Insidious Transmission of a Stress-Related Neuroadaptation

Frontiers in behavioral neuroscience, 2020-10, Vol.14, p.564054-564054

2020

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Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP

Neuron (Cambridge, Mass.), 1999-08, Vol.23 (4), p.787-798

1999

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Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward

Addiction neuroscience, 2022-03, Vol.1, p.100005, Article 100005

2022

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Characterization of individual mouse cerebrospinal fluid proteomes

Proteomics (Weinheim), 2014-05, Vol.14 (9), p.1102-1106

2014

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Dynorphin--still an extraordinarily potent opioid peptide

Kinase cascades and ligand-directed signaling at the kappa opioid receptor

Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor

Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system

Regulation of Gonadotropin-Releasing Hormone Secretion by Kisspeptin/Dynorphin/Neurokinin B Neurons in the Arcuate Nucleus of the Mouse

Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons

Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive

Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking

Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling

Social Defeat Stress-Induced Behavioral Responses are Mediated by the Endogenous Kappa Opioid System

Stress produces aversion and potentiates cocaine reward by releasing endogenous dynorphins in the ventral striatum to locally stimulate serotonin reuptake

Partial Infraorbital Nerve Ligation as a Model of Trigeminal Nerve Injury in the Mouse: Behavioral, Neural, and Glial Reactions

The therapeutic potential of κ-opioids for treatment of pain and addiction

CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior

Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase

Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes

Repeated Administration of Norbinaltorphimine Produces Cumulative Kappa Opioid Receptor Inactivation

Kappa-opioid antagonists as stress resilience medications for the treatment of alcohol use disorders

6.1 Molecular Pharmacology of Opioids: Chronic Stress and Developmental Exposures

Repeated swim stress induces kappa opioid-mediated activation of extracellular signal-regulated kinase 1/2

Disruption of Dopamine Neuron Activity Pattern Regulation through Selective Expression of a Human KCNN3 Mutation

Insidious Transmission of a Stress-Related Neuroadaptation

Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP

Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward

Characterization of individual mouse cerebrospinal fluid proteomes

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