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Overview of the immune response

Journal of allergy and clinical immunology, 2010-02, Vol.125 (2), p.S3-S23

Chaplin, David D., MD, PhD

2010

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IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (31), p.12768-12773

2013

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The development and use of vascular targeted therapy in ovarian cancer

Gynecologic oncology, 2017-05, Vol.145 (2), p.393-406

2017

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A review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P)

Expert opinion on investigational drugs, 2009-02, Vol.18 (2), p.189-197

2009

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Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3′-hydroxy-4′-methoxyphenyl)-3-(3″,4″,5″-trimethoxybenzoyl)-6-methoxyindole (OXi8006)

Bioorganic & medicinal chemistry, 2013-11, Vol.21 (21), p.6831-6843

2013

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The Peruvian Industrial Labor Force

Chaplin, David

2015

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AMP‐activated protein kinase enhances the phagocytic ability of macrophages and neutrophils

The FASEB journal, 2011-12, Vol.25 (12), p.4358-4368

2011

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Vascular‐targeting therapies for treatment of malignant disease

Cancer, 2004-06, Vol.100 (12), p.2491-2499

2004

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Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells

The Journal of immunology (1950), 2012-04, Vol.188 (7), p.3107-3115

2012

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Neutrophils Produce Interleukin 17A (IL-17A) in a Dectin-1- and IL-23-Dependent Manner during Invasive Fungal Infection

Infection and Immunity, 2011-10, Vol.79 (10), p.3966-3977

2011

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Inflammasome-Derived IL-1 beta Regulates the Production of GM-CSF by CD4+ T Cells and gamma delta T Cells

The Journal of immunology (1950), 2012-04, Vol.188 (7), p.3107-3115

2012

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Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics

Scientific reports, 2018-07, Vol.8 (1), p.10340-16, Article 10340

2018

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Critical role of macrophages and their activation via MyD88-NFκB signaling in lung innate immunity to Mycoplasma pneumoniae

PloS one, 2010-12, Vol.5 (12), p.e14417-e14417

2010

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Tumor Immune Evasion

Science (American Association for the Advancement of Science), 2010-05, Vol.328 (5979), p.697-698

2010

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Subsets of airway myeloid-derived regulatory cells distinguish mild asthma from chronic obstructive pulmonary disease

Journal of allergy and clinical immunology, 2015-02, Vol.135 (2), p.413-424.e15

2015

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Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

Nature immunology, 2008-02, Vol.9 (2), p.166-175

2008

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Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors

Science (American Association for the Advancement of Science), 2006-09, Vol.313 (5794), p.1785-1787

2006

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Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization

Journal of medicinal chemistry, 2019-06, Vol.62 (11), p.5594-5615

2019

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Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents

Bioorganic & medicinal chemistry, 2016-03, Vol.24 (5), p.938-956

2016

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DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES

Annual review of immunology, 1999-01, Vol.17 (1), p.399-433

1999

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Bioreductively Activatable Prodrug Conjugates of Combretastatin A‑1 and Combretastatin A‑4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia

Journal of natural products (Washington, D.C.), 2020-04, Vol.83 (4), p.937-954

2020

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Combretastatin A4 phosphate: background and current clinical status

Expert opinion on investigational drugs, 2004-09, Vol.13 (9), p.1171-1182

2004

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Toll-like receptor 4 engagement inhibits adenosine 5'-monophosphate-activated protein kinase activation through a high mobility group box 1 protein-dependent mechanism

Molecular medicine (Cambridge, Mass.), 2012-05, Vol.18 (4), p.659-668

2012

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Low-dose metronomic cyclophosphamide combined with vascular disrupting therapy induces potent antitumor activity in preclinical human tumor xenograft models

Molecular cancer therapeutics, 2009-10, Vol.8 (10), p.2872-2881

2009

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Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents

Bioorganic & medicinal chemistry, 2013-12, Vol.21 (24), p.8019-8032

2013

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Overview of the immune response

IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis

The development and use of vascular targeted therapy in ovarian cancer

A review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P)

Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3′-hydroxy-4′-methoxyphenyl)-3-(3″,4″,5″-trimethoxybenzoyl)-6-methoxyindole (OXi8006)

The Peruvian Industrial Labor Force

AMP‐activated protein kinase enhances the phagocytic ability of macrophages and neutrophils

Vascular‐targeting therapies for treatment of malignant disease

Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells

Neutrophils Produce Interleukin 17A (IL-17A) in a Dectin-1- and IL-23-Dependent Manner during Invasive Fungal Infection

Inflammasome-Derived IL-1 beta Regulates the Production of GM-CSF by CD4+ T Cells and gamma delta T Cells

Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics

Critical role of macrophages and their activation via MyD88-NFκB signaling in lung innate immunity to Mycoplasma pneumoniae

Tumor Immune Evasion

Subsets of airway myeloid-derived regulatory cells distinguish mild asthma from chronic obstructive pulmonary disease

Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors

Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization

Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents

DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES

Bioreductively Activatable Prodrug Conjugates of Combretastatin A‑1 and Combretastatin A‑4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia

Combretastatin A4 phosphate: background and current clinical status

Toll-like receptor 4 engagement inhibits adenosine 5'-monophosphate-activated protein kinase activation through a high mobility group box 1 protein-dependent mechanism

Low-dose metronomic cyclophosphamide combined with vascular disrupting therapy induces potent antitumor activity in preclinical human tumor xenograft models

Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents

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