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Proline metabolism and transport in retinal health and disease

Amino acids, 2021-12, Vol.53 (12), p.1789-1806

2021

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Proline mediates metabolic communication between retinal pigment epithelial cells and the retina

The Journal of biological chemistry, 2019-06, Vol.294 (26), p.10278-10289

2019

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Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side

The Journal of biological chemistry, 2017-08, Vol.292 (31), p.12895-12905

2017

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Targeted adaptive long-read sequencing for discovery of complex phased variants in inherited retinal disease patients

Scientific reports, 2023-05, Vol.13 (1), p.8535-8535, Article 8535

2023

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Quantitative assessment of choriocapillaris flow deficits in diabetic retinopathy: A swept-source optical coherence tomography angiography study

PloS one, 2020-12, Vol.15 (12), p.e0243830-e0243830

2020

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Familial co-segregation and the emerging role of long-read sequencing to re-classify variants of uncertain significance in inherited retinal diseases

Npj genomic medicine, 2023-08, Vol.8 (1), p.20-20, Article 20

2023

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Noninvasive imaging of retinal morphology and microvasculature in obese mice using optical coherence tomography and optical microangiography

Investigative ophthalmology & visual science, 2014-02, Vol.55 (2), p.1024-1030

2014

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Retinal disease: How to use proteomics to speed up diagnosis and metabolomics to slow down degeneration

EBioMedicine, 2020-03, Vol.53, p.102687-102687, Article 102687

2020

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Re: Yahya et al.: Late-onset autosomal dominant macular degeneration caused by deletion of the CRX gene (Ophthalmology. 2023;130:68-76)

Ophthalmology (Rochester, Minn.), 2023-03, Vol.130 (3), p.e9-e9

2023

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User-guided segmentation for volumetric retinal optical coherence tomography images

Journal of biomedical optics, 2014-08, Vol.19 (8), p.086020-086020

2014

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Microvascular Changes in the Choriocapillaris of Diabetic Patients Without Retinopathy Investigated by Swept-Source OCT Angiography

Investigative ophthalmology & visual science, 2020-03, Vol.61 (3), p.50-50

2020

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Familial retinal arteriolar tortuosity and quantification of vascular tortuosity using swept-source optical coherence tomography angiography

American journal of ophthalmology case reports, 2019-06, Vol.14, p.74-78

2019

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Proline provides a nitrogen source in the retinal pigment epithelium to synthesize and export amino acids for the neural retina

The Journal of biological chemistry, 2023-11, Vol.299 (11), p.105275-105275, Article 105275

2023

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Retinal Neovascularization and Endogenous Fungal Endophthalmitis in Intravenous Drug Users

Ophthalmology (Rochester, Minn.), 2014-09, Vol.121 (9), p.1847-1848.e2

2014

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Sorsby fundus dystrophy: Insights from the past and looking to the future

Journal of neuroscience research, 2019-01, Vol.97 (1), p.88-97

2019

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Multimodal High-Resolution Imaging in Retinitis Pigmentosa: A Comparison Between Optoretinography, Cone Density, and Visual Sensitivity

Investigative ophthalmology & visual science, 2024-08, Vol.65 (10), p.45

2024

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CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration

Investigative ophthalmology & visual science, 2024-04, Vol.65 (4), p.43-43

2024

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Poster Session II: Can a drug for liver disease be used to treat Age-Related Macular Degeneration?

Journal of vision (Charlottesville, Va.), 2023-12, Vol.23 (15), p.67

2023

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Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium

Proceedings of the National Academy of Sciences - PNAS, 2016-12, Vol.113 (51), p.14710-14715

2016

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Inhibition of Mitochondrial Respiration Impairs Nutrient Consumption and Metabolite Transport in Human Retinal Pigment Epithelium

Journal of proteome research, 2021-01, Vol.20 (1), p.909-922

2021

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Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux

The Journal of biological chemistry, 2024-10, Vol.300 (10), p.107772, Article 107772

2024

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CAPTCHA as a Visual Performance Metric in Active Macular Disease

Journal of ophthalmology, 2019-01, Vol.2019 (2019), p.1-6

2019

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Reassessing retinal pigment epithelial ketogenesis: Enzymatic assays for ketone body levels provide inaccurate results

Experimental eye research, 2024-08, Vol.245, p.109966-109966, Article 109966

2024

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The Current State of Genetic Testing Platforms for Inherited Retinal Diseases

Ophthalmology retina, 2022-08, Vol.6 (8), p.702-710

2022

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Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye

Proline metabolism and transport in retinal health and disease

Proline mediates metabolic communication between retinal pigment epithelial cells and the retina

Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side

Targeted adaptive long-read sequencing for discovery of complex phased variants in inherited retinal disease patients

Quantitative assessment of choriocapillaris flow deficits in diabetic retinopathy: A swept-source optical coherence tomography angiography study

Familial co-segregation and the emerging role of long-read sequencing to re-classify variants of uncertain significance in inherited retinal diseases

Noninvasive imaging of retinal morphology and microvasculature in obese mice using optical coherence tomography and optical microangiography

Retinal disease: How to use proteomics to speed up diagnosis and metabolomics to slow down degeneration

Re: Yahya et al.: Late-onset autosomal dominant macular degeneration caused by deletion of the CRX gene (Ophthalmology. 2023;130:68-76)

User-guided segmentation for volumetric retinal optical coherence tomography images

Microvascular Changes in the Choriocapillaris of Diabetic Patients Without Retinopathy Investigated by Swept-Source OCT Angiography

Familial retinal arteriolar tortuosity and quantification of vascular tortuosity using swept-source optical coherence tomography angiography

Proline provides a nitrogen source in the retinal pigment epithelium to synthesize and export amino acids for the neural retina

Retinal Neovascularization and Endogenous Fungal Endophthalmitis in Intravenous Drug Users

Sorsby fundus dystrophy: Insights from the past and looking to the future

Multimodal High-Resolution Imaging in Retinitis Pigmentosa: A Comparison Between Optoretinography, Cone Density, and Visual Sensitivity

CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration

Poster Session II: Can a drug for liver disease be used to treat Age-Related Macular Degeneration?

Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium

Inhibition of Mitochondrial Respiration Impairs Nutrient Consumption and Metabolite Transport in Human Retinal Pigment Epithelium

Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux

CAPTCHA as a Visual Performance Metric in Active Macular Disease

Reassessing retinal pigment epithelial ketogenesis: Enzymatic assays for ketone body levels provide inaccurate results

The Current State of Genetic Testing Platforms for Inherited Retinal Diseases

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