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Characterization of HKI-272 covalent binding to human serum albumin

Drug metabolism and disposition, 2010-07, Vol.38 (7), p.1083

2010

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Metabolic disposition of [14C]bazedoxifene in healthy postmenopausal women

Drug metabolism and disposition, 2009-06, Vol.37 (6), p.1219

2009

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In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases

Drug metabolism and disposition, 2007-12, Vol.35 (12), p.2203

2007

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Effects of pethoxamid treatment on the disposition of thyroxine in rats

Toxicology and applied pharmacology, 2024-06, Vol.487, p.116959-116959, Article 116959

2024

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Molecular and Pharmacological Properties of a Potent and Selective Novel Nonsteroidal Progesterone Receptor Agonist Tanaproget

The Journal of biological chemistry, 2005-08, Vol.280 (31), p.28468-28475

2005

Volltextzugriff (PDF)

Determination of enzymatic kinetics of metabolism of dimethoate and omethoate in rats and humans

Xenobiotica, 2023-04, Vol.ahead-of-print (ahead-of-print), p.1-9

2023

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A physiologically-based pharmacokinetic/pharmacodynamic (PBPK/PD) model for the insecticide dimethoate

Xenobiotica, 2023-05, Vol.53 (5), p.382-395

2023

Volltextzugriff (PDF)

Toxicokinetic testing strategies to demonstrate bone marrow exposure in in vivo micronucleus study for genotoxicity assessment of agrochemicals

Regulatory toxicology and pharmacology, 2020-02, Vol.110, p.104552, Article 104552

2020

Volltextzugriff (PDF)

Determination of offspring NOAEL for zeta-cypermethrin using internal exposure data from rat developmental neurotoxicity studies

Regulatory toxicology and pharmacology, 2019-11, Vol.108, p.104425, Article 104425

2019

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The pharmacokinetic properties of bifenthrin in the rat following multiple routes of exposure

Pest management science, 2015-06, Vol.71 (6), p.835-841

2015

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NMR characterization of an S-linked glucuronide metabolite of the potent, novel, nonsteroidal progesterone agonist tanaproget

Drug metabolism and disposition, 2006-08, Vol.34 (8), p.1283

2006

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Establishing maximum tolerated doses for a 2-year combined chronic/carcinogenicity rat study based on toxicokinetic and toxicity gender differences

Regulatory toxicology and pharmacology, 2017-11, Vol.90, p.153-159

2017

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Pyrethroid neurotoxicity studies with bifenthrin indicate a mixed Type I/II mode of action

Pest management science, 2019-04, Vol.75 (4), p.1190-1197

2019

Volltextzugriff (PDF)

In vitro metabolism of [14C]-benalaxyl in hepatocytes of rats, dogs and humans

Regulatory toxicology and pharmacology, 2017-03, Vol.84, p.26-34

2017

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Locomotor activity and tissue levels following acute administration of lambda- and gamma-cyhalothrin in rats

Toxicology and applied pharmacology, 2016-12, Vol.313, p.97-103

2016

Volltextzugriff (PDF)

Alternate Strategies to Obtain Mass Balance without the Use of Radiolabeled Compounds: Application of Quantitative Fluorine (19F) Nuclear Magnetic Resonance (NMR) Spectroscopy in Metabolism Studies

Chemical research in toxicology, 2012-03, Vol.25 (3), p.572-583

2012

Volltextzugriff (PDF)

Mechanism study of N-dephenylation mediated through a N-para-hydroxy metabolite

Current drug discovery technologies, 2006-06, Vol.3 (2), p.101

2006

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In vitro metabolism, permeability, and efflux of bazedoxifene in humans

Drug metabolism and disposition, 2010-09, Vol.38 (9), p.1471

2010

Volltextzugriff (PDF)

Alternate Strategies to Obtain Mass Balance without the Use of Radiolabeled Compounds: Application of Quantitative Fluorine ( super(19)F) Nuclear Magnetic Resonance (NMR) Spectroscopy in Metabolism Studies

Chemical research in toxicology, 2012-03, Vol.25 (3), p.572-583-572-583

2012

Volltextzugriff (PDF)

In vitro metabolism and identification of human enzymes involved in the metabolism of methylnaltrexone

Drug metabolism and disposition, 2010-05, Vol.38 (5), p.801

2010

Volltextzugriff (PDF)

Species differences in the formation of vabicaserin carbamoyl glucuronide

Drug metabolism and disposition, 2010-04, Vol.38 (4), p.581

2010

Volltextzugriff (PDF)

Metabolism of intravenous methylnaltrexone in mice, rats, dogs, and humans

Drug metabolism and disposition, 2010-04, Vol.38 (4), p.606

2010

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Metabolism of vabicaserin in mice, rats, dogs, monkeys, and humans

Drug metabolism and disposition, 2010-12, Vol.38 (12), p.2266

2010

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Reversible covalent binding of neratinib to human serum albumin in vitro

Drug metabolism letters, 2010-12, Vol.4 (4), p.220

2010

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Digoxin Disposition in Elderly Humans with Hypochlorhydria

Journal of clinical pharmacology, 1994-07, Vol.34 (7), p.734-741

1994

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Characterization of HKI-272 covalent binding to human serum albumin

Metabolic disposition of [14C]bazedoxifene in healthy postmenopausal women

In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases

Effects of pethoxamid treatment on the disposition of thyroxine in rats

Molecular and Pharmacological Properties of a Potent and Selective Novel Nonsteroidal Progesterone Receptor Agonist Tanaproget

Determination of enzymatic kinetics of metabolism of dimethoate and omethoate in rats and humans

A physiologically-based pharmacokinetic/pharmacodynamic (PBPK/PD) model for the insecticide dimethoate

Toxicokinetic testing strategies to demonstrate bone marrow exposure in in vivo micronucleus study for genotoxicity assessment of agrochemicals

Determination of offspring NOAEL for zeta-cypermethrin using internal exposure data from rat developmental neurotoxicity studies

The pharmacokinetic properties of bifenthrin in the rat following multiple routes of exposure

NMR characterization of an S-linked glucuronide metabolite of the potent, novel, nonsteroidal progesterone agonist tanaproget

Establishing maximum tolerated doses for a 2-year combined chronic/carcinogenicity rat study based on toxicokinetic and toxicity gender differences

Pyrethroid neurotoxicity studies with bifenthrin indicate a mixed Type I/II mode of action

In vitro metabolism of [14C]-benalaxyl in hepatocytes of rats, dogs and humans

Locomotor activity and tissue levels following acute administration of lambda- and gamma-cyhalothrin in rats

Alternate Strategies to Obtain Mass Balance without the Use of Radiolabeled Compounds: Application of Quantitative Fluorine (19F) Nuclear Magnetic Resonance (NMR) Spectroscopy in Metabolism Studies

Mechanism study of N-dephenylation mediated through a N-para-hydroxy metabolite

In vitro metabolism, permeability, and efflux of bazedoxifene in humans

Alternate Strategies to Obtain Mass Balance without the Use of Radiolabeled Compounds: Application of Quantitative Fluorine ( super(19)F) Nuclear Magnetic Resonance (NMR) Spectroscopy in Metabolism Studies

In vitro metabolism and identification of human enzymes involved in the metabolism of methylnaltrexone

Species differences in the formation of vabicaserin carbamoyl glucuronide

Metabolism of intravenous methylnaltrexone in mice, rats, dogs, and humans

Metabolism of vabicaserin in mice, rats, dogs, monkeys, and humans

Reversible covalent binding of neratinib to human serum albumin in vitro

Digoxin Disposition in Elderly Humans with Hypochlorhydria

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