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RNA Splicing and Disease: Animal Models to Therapies

Trends in genetics, 2019-01, Vol.35 (1), p.68-87

2019

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Psychological success: When the career is a calling

Journal of organizational behavior, 2005-03, Vol.26 (2), p.155-176

2005

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A Review of Developmental Networks: Incorporating a Mutuality Perspective

Journal of management, 2012-01, Vol.38 (1), p.210-242

2012

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Heat increases full-length SMN splicing: promise for splice-augmenting therapies for SMA

Human genetics, 2022-02, Vol.141 (2), p.239-256

2022

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An Ecological Systems Perspective on Mentoring at Work: A Review and Future Prospects

The Academy of Management annals, 2011-01, Vol.5 (1), p.519-570

2011

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SMN regulation in SMA and in response to stress: new paradigms and therapeutic possibilities

Human genetics, 2017-09, Vol.136 (9), p.1173-1191

2017

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The Splicing Factor FUBP1 Is Required for the Efficient Splicing of Oncogene MDM2 Pre-mRNA

The Journal of biological chemistry, 2014-06, Vol.289 (25), p.17350-17364

2014

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Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct ways

PloS one, 2014-08, Vol.9 (8), p.e104444-e104444

2014

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SRSF2 Regulation of MDM2 Reveals Splicing as a Therapeutic Vulnerability of the p53 Pathway

Molecular cancer research, 2020-02, Vol.18 (2), p.194-203

2020

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miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR

Science signaling, 2013-07, Vol.6 (286), p.ra63

2013

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Mouse models of SMA: tools for disease characterization and therapeutic development

Human genetics, 2012-08, Vol.131 (8), p.1277-1293

2012

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Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage

Nucleic acids research, 2015-04, Vol.43 (8), p.4202-4218

2015

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Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model

Human molecular genetics, 2012-10, Vol.21 (19), p.4301-4313

2012

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Alternatively Spliced Landscape of PPARγ mRNA in Podocytes Is Distinct from Adipose Tissue

Cells (Basel, Switzerland), 2022-11, Vol.11 (21), p.3455

2022

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Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4

Cancer research (Chicago, Ill.), 2006-10, Vol.66 (19), p.9502-9508

2006

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Splicing of the Survival Motor Neuron genes and implications for treatment of SMA

Frontiers in bioscience (Landmark. Print), 2010-06, Vol.15 (3), p.1191-1204

2010

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Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype

Human molecular genetics, 2012-02, Vol.21 (4), p.811-825

2012

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DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition

Cancer discovery, 2013-10, Vol.3 (10), p.1172-1189

2013

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Regulation of photoreceptor gene transcription via a highly conserved transcriptional regulatory element by vsx gene products

Molecular vision, 2016-12, Vol.22, p.1421-1428

2016

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Stress-Induced Isoforms of MDM2 and MDM4 Correlate with High-Grade Disease and an Altered Splicing Network in Pediatric Rhabdomyosarcoma

Neoplasia (New York, N.Y.), 2013-09, Vol.15 (9), p.1049-IN8

2013

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Leveraging gene therapy to achieve long-term continuous or controllable expression of biotherapeutics

Science advances, 2022-07, Vol.8 (28), p.eabm1890

2022

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Splice-switching of the insulin receptor pre-mRNA alleviates tumorigenic hallmarks in rhabdomyosarcoma

NPJ precision oncology, 2022-01, Vol.6 (1), p.1-1, Article 1

2022

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The Maven of Mentoring Speaks: Kathy E. Kram Reflects on Her Career and the Field

Journal of management inquiry, 2011-03, Vol.20 (1), p.24-33

Chandler, Dawn E.

2011

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Intron 7 conserved sequence elements regulate the splicing of the SMN genes

Human genetics, 2009-12, Vol.126 (6), p.833-841

2009

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Never quite good enough: The paradox of sticky developmental relationships for elite university graduates

Journal of vocational behavior, 2008-04, Vol.72 (2), p.207-224

2008

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RNA Splicing and Disease: Animal Models to Therapies

Psychological success: When the career is a calling

A Review of Developmental Networks: Incorporating a Mutuality Perspective

Heat increases full-length SMN splicing: promise for splice-augmenting therapies for SMA

An Ecological Systems Perspective on Mentoring at Work: A Review and Future Prospects

SMN regulation in SMA and in response to stress: new paradigms and therapeutic possibilities

The Splicing Factor FUBP1 Is Required for the Efficient Splicing of Oncogene MDM2 Pre-mRNA

Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct ways

SRSF2 Regulation of MDM2 Reveals Splicing as a Therapeutic Vulnerability of the p53 Pathway

miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR

Mouse models of SMA: tools for disease characterization and therapeutic development

Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage

Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model

Alternatively Spliced Landscape of PPARγ mRNA in Podocytes Is Distinct from Adipose Tissue

Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4

Splicing of the Survival Motor Neuron genes and implications for treatment of SMA

Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype

DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition

Regulation of photoreceptor gene transcription via a highly conserved transcriptional regulatory element by vsx gene products

Stress-Induced Isoforms of MDM2 and MDM4 Correlate with High-Grade Disease and an Altered Splicing Network in Pediatric Rhabdomyosarcoma

Leveraging gene therapy to achieve long-term continuous or controllable expression of biotherapeutics

Splice-switching of the insulin receptor pre-mRNA alleviates tumorigenic hallmarks in rhabdomyosarcoma

The Maven of Mentoring Speaks: Kathy E. Kram Reflects on Her Career and the Field

Intron 7 conserved sequence elements regulate the splicing of the SMN genes

Never quite good enough: The paradox of sticky developmental relationships for elite university graduates

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