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Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

Nature communications, 2019-04, Vol.10 (1), p.1523-1523, Article 1523

2019

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SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (45), p.28344-28354

2020

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MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

Cell reports (Cambridge), 2021-01, Vol.34 (2), p.108628-108628, Article 108628

2021

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PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1

Cell, 2015-06, Vol.161 (6), p.1293-1305

2015

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NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses

Cell host & microbe, 2016-04, Vol.19 (4), p.515-528

2016

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Activation of the Interferon Pathway in Trophoblast Cells Productively Infected with SARS-CoV-2

Stem cells and development, 2023-05, Vol.32 (9-10), p.225

2023

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Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling

PloS one, 2008-01, Vol.3 (1), p.e1487-e1487

2008

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Host cell factors in HIV replication: meta-analysis of genome-wide studies

PLoS pathogens, 2009-05, Vol.5 (5), p.e1000437-e1000437

2009

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HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2

PLoS pathogens, 2011-03, Vol.7 (3), p.e1001313-e1001313

2011

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Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targets

Molecular systems biology, 2021-11, Vol.17 (11), p.n/a

2021

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A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor

PLoS pathogens, 2021-11, Vol.17 (11), p.e1009409-e1009409

2021

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Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a Cure

Viruses, 2023-12, Vol.15 (12), p.2435

2023

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Human host factors required for influenza virus replication

Nature (London), 2010-02, Vol.463 (7282), p.813-817

2010

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Sensor Sensibility-HIV-1 and the Innate Immune Response

Cells (Basel, Switzerland), 2020-01, Vol.9 (1), p.254

2020

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SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir

PLoS biology, 2022-11, Vol.20 (11), p.e3001845-e3001845

2022

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Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA

Molecular cell, 2022-08, Vol.82 (15), p.2871-2884.e6

2022

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BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency

Cell host & microbe, 2015-09, Vol.18 (3), p.345-353

2015

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Drug target prediction through deep learning functional representation of gene signatures

Nature communications, 2024-02, Vol.15 (1), p.1853-1853, Article 1853

2024

Volltextzugriff (PDF)

Identification of global inhibitors of cellular glycosylation

Nature communications, 2023-02, Vol.14 (1), p.948-948, Article 948

2023

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A probability-based approach for the analysis of large-scale RNAi screens

Nature methods, 2007-10, Vol.4 (10), p.847-849

2007

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HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses

eLife, 2019-02, Vol.8

2019

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HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2

Retrovirology, 2015-08, Vol.12 (1), p.74-74, Article 74

2015

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Minimizing the risk of reporting false positives in large-scale RNAi screens

Nature methods, 2006-10, Vol.3 (10), p.777-779

2006

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RIOK3 is an adaptor protein required for IRF3-mediated antiviral type I interferon production

Journal of virology, 2014-07, Vol.88 (14), p.7987-7997

2014

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Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1

NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses

Activation of the Interferon Pathway in Trophoblast Cells Productively Infected with SARS-CoV-2

Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling

Host cell factors in HIV replication: meta-analysis of genome-wide studies

HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2

Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targets

A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor

Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a Cure

Human host factors required for influenza virus replication

Sensor Sensibility-HIV-1 and the Innate Immune Response

SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir

Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA

BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency

Drug target prediction through deep learning functional representation of gene signatures

Identification of global inhibitors of cellular glycosylation

A probability-based approach for the analysis of large-scale RNAi screens

HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses

HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2

Minimizing the risk of reporting false positives in large-scale RNAi screens

RIOK3 is an adaptor protein required for IRF3-mediated antiviral type I interferon production

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