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Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein

eLife, 2024-05, Vol.12

2024

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Zika virus nonstructural protein 5 residue R681 is critical for dimer formation and enzymatic activity

FEBS letters, 2019-06, Vol.593 (12), p.1272-1291

2019

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Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

PLoS neglected tropical diseases, 2016-08, Vol.10 (8), p.e0004851-e0004851

2016

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Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin

International Journal of Biomaterials, 2016-01, Vol.2016 (2016), p.93-107

2016

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Dengue Virus and Zika Virus Serological Cross-reactivity and Their Impact on Pathogenesis in Mice

The Journal of infectious diseases, 2019-01, Vol.219 (2), p.223-233

2019

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Optimizing celgosivir therapy in mouse models of dengue virus infection of serotypes 1 and 2: The search for a window for potential therapeutic efficacy

Antiviral research, 2016-03, Vol.127, p.10-19

2016

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The Value of Hepatic Scintigraphy in the Diagnosis of Biliary Atresia

Frontiers in pediatrics, 2022-05, Vol.10, p.874809

2022

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Dosimetric impact of phase shifts on Radixact Synchrony tracking system with patient‐specific breathing patterns

Journal of applied clinical medical physics, 2022-06, Vol.23 (6), p.e13600-n/a

2022

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A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation

Virology (New York, N.Y.), 2023-06, Vol.583, p.1-13

2023

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A Nuclear Transport Inhibitor That Modulates the Unfolded Protein Response and Provides In Vivo Protection Against Lethal Dengue virus Infection

The Journal of infectious diseases, 2014-12, Vol.210 (11), p.1780-1791

2014

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Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation

Antiviral research, 2018-06, Vol.154, p.87-96

2018

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Structure-guided Discovery of a Novel Non-peptide Inhibitor of Dengue Virus NS2B-NS3 Protease

Chemical biology & drug design, 2015-09, Vol.86 (3), p.255-264

2015

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Effect of a Prodrug of the Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate on the Growth of Androgen-Independent Prostate Cancer In Vivo

Nutrition and cancer, 2008, Vol.60 (4), p.483-491

2008

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Dengue Virus Infection with Highly Neutralizing Levels of Cross-Reactive Antibodies Causes Acute Lethal Small Intestinal Pathology without a High Level of Viremia in Mice

Journal of virology, 2015-06, Vol.89 (11), p.5847-5861

2015

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Carbazole to indolazepinone scaffold morphing leads to potent cell-active dengue antivirals

European journal of medicinal chemistry, 2024-03, Vol.268, p.116213-116213, Article 116213

2024

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Experimental evidence for a high rate of maternal-fetal transmission of dengue virus in the presence of antibodies in immunocompromised mice

EBioMedicine, 2022-03, Vol.77, p.103930-103930, Article 103930

2022

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Structural basis of Zika virus NS1 multimerization and human antibody recognition

npj Viruses, 2024-04, Vol.2 (1), p.1-9, Article 14

2024

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Guillain-Barré syndrome in children – High occurrence of Miller Fisher syndrome in East Asian region

Brain & development (Tokyo. 1979), 2022-11, Vol.44 (10), p.715-724

2022

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The Potential Role of the ZIKV NS5 Nuclear Spherical-Shell Structures in Cell Type-Specific Host Immune Modulation during ZIKV Infection

Cells (Basel, Switzerland), 2019-11, Vol.8 (12), p.1519

2019

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Cell-active carbazole derivatives as inhibitors of the zika virus protease

European journal of medicinal chemistry, 2019-10, Vol.180, p.536-545

2019

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Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents

European journal of medicinal chemistry, 2021-01, Vol.210, p.112992, Article 112992

2021

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Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase

ACS medicinal chemistry letters, 2020-05, Vol.11 (5), p.773-782

2020

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Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin‑α and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells

ACS infectious diseases, 2019-06, Vol.5 (6), p.932-948

2019

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Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication

Journal of virology, 2015-10, Vol.89 (20), p.10717-10721

2015

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Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial

Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein

Zika virus nonstructural protein 5 residue R681 is critical for dimer formation and enzymatic activity

Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin

Dengue Virus and Zika Virus Serological Cross-reactivity and Their Impact on Pathogenesis in Mice

Optimizing celgosivir therapy in mouse models of dengue virus infection of serotypes 1 and 2: The search for a window for potential therapeutic efficacy

The Value of Hepatic Scintigraphy in the Diagnosis of Biliary Atresia

Dosimetric impact of phase shifts on Radixact Synchrony tracking system with patient‐specific breathing patterns

A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation

A Nuclear Transport Inhibitor That Modulates the Unfolded Protein Response and Provides In Vivo Protection Against Lethal Dengue virus Infection

Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation

Structure-guided Discovery of a Novel Non-peptide Inhibitor of Dengue Virus NS2B-NS3 Protease

Effect of a Prodrug of the Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate on the Growth of Androgen-Independent Prostate Cancer In Vivo

Dengue Virus Infection with Highly Neutralizing Levels of Cross-Reactive Antibodies Causes Acute Lethal Small Intestinal Pathology without a High Level of Viremia in Mice

Carbazole to indolazepinone scaffold morphing leads to potent cell-active dengue antivirals

Experimental evidence for a high rate of maternal-fetal transmission of dengue virus in the presence of antibodies in immunocompromised mice

Structural basis of Zika virus NS1 multimerization and human antibody recognition

Guillain-Barré syndrome in children – High occurrence of Miller Fisher syndrome in East Asian region

The Potential Role of the ZIKV NS5 Nuclear Spherical-Shell Structures in Cell Type-Specific Host Immune Modulation during ZIKV Infection

Cell-active carbazole derivatives as inhibitors of the zika virus protease

Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents

Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase

Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin‑α and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells

Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication

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