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Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy

Signal transduction and targeted therapy, 2021-08, Vol.6 (1), p.323-323, Article 323

2021

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Unraveling the enigma: progress towards understanding the coronin family of actin regulators

Trends in cell biology, 2011-08, Vol.21 (8), p.481-488

2011

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Regulation of Adhesion Dynamics by Calpain-mediated Proteolysis of Focal Adhesion Kinase (FAK)

The Journal of biological chemistry, 2010-04, Vol.285 (15), p.11418-11426

2010

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FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion

The Journal of cell biology, 2009-04, Vol.185 (2), p.357-370

2009

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Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (36), p.17990-18000

2019

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CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Nature communications, 2020-05, Vol.11 (1), p.2641-18, Article 2641

2020

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A functional genetic screen defines the AKT-induced senescence signaling network

Cell death and differentiation, 2020-02, Vol.27 (2), p.725-741

2020

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LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma

Cancer cell, 2012-06, Vol.21 (6), p.751-764

2012

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Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

Oncotarget, 2016-08, Vol.7 (31), p.49800-49818

2016

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Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation

eLife, 2022-06, Vol.11

2022

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The Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer

International journal of molecular sciences, 2017-01, Vol.18 (1), p.210-210

2017

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Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin

Biochemical journal, 2012-05, Vol.444 (1), p.89-96

2012

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Cystathionine β-Synthase in Physiology and Cancer

BioMed research international, 2018-01, Vol.2018 (2018), p.1-11

2018

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Oncogene-induced senescence: From biology to therapy

Mechanisms of ageing and development, 2020-04, Vol.187, p.111229-111229, Article 111229

2020

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The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

British journal of cancer, 2021-02, Vol.124 (3), p.616-627

2021

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INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

Cancer discovery, 2024-03, Vol.14 (3), p.446-467

2024

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β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion

Breast cancer research : BCR, 2015-11, Vol.17 (1), p.145-145, Article 145

2015

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Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion

The Journal of cell biology, 2008-03, Vol.180 (5), p.957-971

2008

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Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis

The EMBO journal, 2020-11, Vol.39 (21), p.e105111-n/a

2020

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LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues

The Journal of cell biology, 2014-10, Vol.207 (2), p.299-315

2014

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Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence

Assay and drug development technologies, 2016-09, Vol.14 (7), p.416-428

2016

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IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma

Clinical cancer research, 2015-05, Vol.21 (9), p.2167-2176

2015

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LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues

The Journal of experimental medicine, 2014-11, Vol.211 (12), p.21112-21112OIA68

2014

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Integrins in Cell Migration

Integrins, 2007, Vol.426, p.47-67

2007

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Intravital imaging of a spheroid-based orthotopic model of melanoma in the mouse ear skin

Intravital, 2013-01, Vol.2 (2), p.e25805

2013

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Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy

Unraveling the enigma: progress towards understanding the coronin family of actin regulators

Regulation of Adhesion Dynamics by Calpain-mediated Proteolysis of Focal Adhesion Kinase (FAK)

FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion

Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

A functional genetic screen defines the AKT-induced senescence signaling network

LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation

The Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer

Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin

Cystathionine β-Synthase in Physiology and Cancer

Oncogene-induced senescence: From biology to therapy

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion

Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis

LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues

Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence

IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma

LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues

Integrins in Cell Migration

Intravital imaging of a spheroid-based orthotopic model of melanoma in the mouse ear skin

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