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Early endosomes and endosomal coatomer are required for autophagy

The Journal of cell biology, 2009-04, Vol.185 (2), p.305-321

2009

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Huntingtin and Huntingtin-Associated Protein 1 Influence Neuronal Calcium Signaling Mediated by Inositol-(1,4,5) Triphosphate Receptor Type 1

Neuron (Cambridge, Mass.), 2003-07, Vol.39 (2), p.227-239

2003

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siRNA Screening of the Kinome Identifies ULK1 as a Multidomain Modulator of Autophagy

The Journal of biological chemistry, 2007-08, Vol.282 (35), p.25464-25474

2007

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Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2

Autophagy, 2013-03, Vol.9 (3), p.361-373

2013

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Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

Journal of cell science, 2006-09, Vol.119 (18), p.3888-3900

2006

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Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death

The Journal of biological chemistry, 2019-09, Vol.294 (39), p.14289-14307

2019

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Blood extracellular vesicles from healthy individuals regulate hematopoietic stem cells as humans age

Aging cell, 2020-11, Vol.19 (11), p.e13245-n/a

2020

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Regulation of autophagosome formation by Rho kinase

Cellular signalling, 2013-01, Vol.25 (1), p.1-11

2013

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Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease

Human molecular genetics, 2002-08, Vol.11 (17), p.1939-1951

2002

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Mitochondrial dynamics and oxidative phosphorylation as critical targets in cancer

Endocrine-related cancer, 2023-01, Vol.30 (1), p.1

2023

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AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms

Molecular and cellular biology, 2018-05, Vol.38 (10)

2018

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Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism

Molecular and Cellular Biology, 2009-01, Vol.29 (1), p.157-171

2009

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IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling

Cellular signalling, 2023-07, Vol.107, p.110684-110684, Article 110684

2023

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Advances in Autophagy Regulatory Mechanisms

Cells (Basel, Switzerland), 2016-06, Vol.5 (2), p.24

2016

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Microtubules Facilitate Autophagosome Formation and Fusion of Autophagosomes with Endosomes

Traffic (Copenhagen, Denmark), 2006-02, Vol.7 (2), p.129-145

2006

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Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids

Cell reports (Cambridge), 2022-08, Vol.40 (7), p.111198-111198, Article 111198

2022

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Lysosomotropism depends on glucose: a chloroquine resistance mechanism

Cell death & disease, 2017-08, Vol.8 (8), p.e3014-e3014

2017

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Early signalling events of autophagy

Essays in biochemistry, 2013-01, Vol.55, p.1-15

2013

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ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases

Cells (Basel, Switzerland), 2019-05, Vol.8 (5), p.475

2019

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RasGRP, a Ras Guanyl Nucleotide-Releasing Protein with Calcium- and Diacylglycerol-Binding Motifs

Science (American Association for the Advancement of Science), 1998-05, Vol.280 (5366), p.1082-1086

1998

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HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons

The European journal of neuroscience, 2004-10, Vol.20 (7), p.1779-1787

2004

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Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior

Human molecular genetics, 2002-04, Vol.11 (8), p.945-959

2002

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A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase

The Journal of biological chemistry, 1999-04, Vol.274 (18), p.12722-12729

1999

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Hypothermic stress leads to activation of Ras-Erk signaling

The Journal of clinical investigation, 1999-05, Vol.103 (9), p.1337-1344

1999

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Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity

Molecular carcinogenesis, 2002-04, Vol.33 (4), p.189-197

2002

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Biochemistry & Molecular Biology
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Cell Line
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Intracellular Signaling Peptides And Proteins - Metabolism
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Mice
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Protein-Serine-Threonine Kinases - Metabolism
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Early endosomes and endosomal coatomer are required for autophagy

Huntingtin and Huntingtin-Associated Protein 1 Influence Neuronal Calcium Signaling Mediated by Inositol-(1,4,5) Triphosphate Receptor Type 1

siRNA Screening of the Kinome Identifies ULK1 as a Multidomain Modulator of Autophagy

Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death

Blood extracellular vesicles from healthy individuals regulate hematopoietic stem cells as humans age

Regulation of autophagosome formation by Rho kinase

Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease

Mitochondrial dynamics and oxidative phosphorylation as critical targets in cancer

AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms

Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism

IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling

Advances in Autophagy Regulatory Mechanisms

Microtubules Facilitate Autophagosome Formation and Fusion of Autophagosomes with Endosomes

Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids

Lysosomotropism depends on glucose: a chloroquine resistance mechanism

Early signalling events of autophagy

ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases

RasGRP, a Ras Guanyl Nucleotide-Releasing Protein with Calcium- and Diacylglycerol-Binding Motifs

HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons

Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior

A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase

Hypothermic stress leads to activation of Ras-Erk signaling

Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity

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