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Conditional Depletion of STN1 in Mouse Embryonic Fibroblasts

Bio-protocol, 2024-04, Vol.14 (8), p.e4977-e4977

2024

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Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers

BMC genomics, 2019-07, Vol.20 (1), p.579-13, Article 579

2019

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Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in

Cell research, 2012-12, Vol.22 (12), p.1681-1695

2012

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Crosstalk between CST and RPA regulates RAD51 activity during replication stress

Nature communications, 2021-11, Vol.12 (1), p.6412-6412, Article 6412

2021

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CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion

The EMBO journal, 2012-05, Vol.31 (10), p.2309-2321

2012

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Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity

The EMBO journal, 2013-05, Vol.32 (10), p.1425-1439

2013

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CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection

Nature communications, 2023-11, Vol.14 (1), p.7882-7882, Article 7882

2023

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The Intrinsically Disordered Region in the Human STN1 OB-Fold Domain Is Important for Protecting Genome Stability

Biology (Basel, Switzerland), 2021-09, Vol.10 (10), p.977

2021

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Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress

Cell reports (Cambridge), 2016-08, Vol.16 (5), p.1300-1314

2016

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Roles of OB-Fold Proteins in Replication Stress

Frontiers in cell and developmental biology, 2020-09, Vol.8

2020

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Molecular insights into replication‐associated genome instabilities caused by CST deficiency

The FASEB journal, 2018-04, Vol.32 (S1), p.522.7-522.7

Chai, Weihang

2018

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Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection

The EMBO journal, 2010-08, Vol.29 (16), p.2788-2801

2010

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Human Flap Endonuclease I Is in Complex with Telomerase and Is Required for Telomerase-mediated Telomere Maintenance

The Journal of biological chemistry, 2009-02, Vol.284 (6), p.3682-3690

2009

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Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress

Cell reports (Cambridge), 2016-08, Vol.16 (7), p.2048-2048

2016

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CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G2 phase

Cell cycle (Georgetown, Tex.), 2012-08, Vol.11 (16), p.3079-3086

2012

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CST in maintaining genome stability: Beyond telomeres

DNA repair, 2021-06, Vol.102, p.103104-103104, Article 103104

2021

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The MLH1 ATPase domain is needed for suppressing aberrant formation of interstitial telomeric sequences

DNA repair, 2018-05, Vol.65, p.20-25

2018

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The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres

EMBO reports, 2006-02, Vol.7 (2), p.225-230

2006

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Human Ku70/80 Associates Physically with Telomerase through Interaction with hTERT

The Journal of biological chemistry, 2002-12, Vol.277 (49), p.47242-47247

2002

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DNA excision repair at telomeres

DNA repair, 2015-12, Vol.36, p.137-145

2015

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Human Telomeres Maintain Their Overhang Length at Senescence

Molecular and Cellular Biology, 2005-03, Vol.25 (6), p.2158-2168

2005

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Mcm10 and Cdc45 Cooperate in Origin Activation in Saccharomyces cerevisiae

Journal of molecular biology, 2004-07, Vol.340 (2), p.195-202

2004

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Human CST complex restricts excessive PrimPol repriming upon UV induced replication stress by suppressing p21

Nucleic acids research, 2024-04, Vol.52 (7), p.3778

2024

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Suppression of STN1 enhances the cytotoxicity of chemotherapeutic agents in cancer cells by elevating DNA damage

Oncology letters, 2016-08, Vol.12 (2), p.800-808

2016

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CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion

The EMBO journal, 2012-05, Vol.31 (10), p.2309-2321

2012

Volltextzugriff (PDF)

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Conditional Depletion of STN1 in Mouse Embryonic Fibroblasts

Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers

Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in

Crosstalk between CST and RPA regulates RAD51 activity during replication stress

CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion

Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity

CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection

The Intrinsically Disordered Region in the Human STN1 OB-Fold Domain Is Important for Protecting Genome Stability

Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress

Roles of OB-Fold Proteins in Replication Stress

Molecular insights into replication‐associated genome instabilities caused by CST deficiency

Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection

Human Flap Endonuclease I Is in Complex with Telomerase and Is Required for Telomerase-mediated Telomere Maintenance

Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress

CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G2 phase

CST in maintaining genome stability: Beyond telomeres

The MLH1 ATPase domain is needed for suppressing aberrant formation of interstitial telomeric sequences

The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres

Human Ku70/80 Associates Physically with Telomerase through Interaction with hTERT

DNA excision repair at telomeres

Human Telomeres Maintain Their Overhang Length at Senescence

Mcm10 and Cdc45 Cooperate in Origin Activation in Saccharomyces cerevisiae

Human CST complex restricts excessive PrimPol repriming upon UV induced replication stress by suppressing p21

Suppression of STN1 enhances the cytotoxicity of chemotherapeutic agents in cancer cells by elevating DNA damage

CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion

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