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Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model

Nature communications, 2019-03, Vol.10 (1), p.1430-1430, Article 1430

2019

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Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade

Nature communications, 2017-04, Vol.8 (1), p.14979-14979, Article 14979

2017

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Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti-PD-1 resistance

The Journal of clinical investigation, 2023-11, Vol.133 (21), p.1-18

2023

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Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis

The Journal of biological chemistry, 2013-03, Vol.288 (10), p.7313-7325

2013

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Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin)

Scientific reports, 2023-08, Vol.13 (1), p.13790-13790, Article 13790

2023

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Dual activity of Minnelide chemosensitize basal/triple negative breast cancer stem cells and reprograms immunosuppressive tumor microenvironment

Scientific reports, 2024-09, Vol.14 (1), p.22487-15, Article 22487

2024

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Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity

Journal for immunotherapy of cancer, 2020-08, Vol.8 (2), p.e001182

2020

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Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms

Pharmacological research, 2014-07, Vol.85, p.45-54

2014

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Celastrol Inhibits Hsp90 Chaperoning of Steroid Receptors by Inducing Fibrillization of the Co-chaperone p23

The Journal of biological chemistry, 2010-02, Vol.285 (6), p.4224-4231

2010

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The Heat Shock Protein 90 Antagonist Novobiocin Interacts with a Previously Unrecognized ATP-binding Domain in the Carboxyl Terminus of the Chaperone

The Journal of biological chemistry, 2000-11, Vol.275 (47), p.37181-37186

2000

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The Cochaperone SGTA (Small Glutamine-rich Tetratricopeptide Repeat-containing Protein Alpha) Demonstrates Regulatory Specificity for the Androgen, Glucocorticoid, and Progesterone Receptors

The Journal of biological chemistry, 2014-05, Vol.289 (22), p.15297-15308

2014

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Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer

iScience, 2023-12, Vol.26 (12), p.108308, Article 108308

2023

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HSP40 Binding Is the First Step in the HSP90 Chaperoning Pathway for the Progesterone Receptor

The Journal of biological chemistry, 2002-04, Vol.277 (14), p.11873-11881

2002

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Analysis of Hsp90 Cochaperone Interactions Reveals a Novel Mechanism for TPR Protein Recognition

Biochemistry (Easton), 2008-03, Vol.47 (9), p.2850-2857

2008

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Dimerization and N-Terminal Domain Proximity Underlie the Function of the Molecular Chaperone Heat Shock Protein 90

Proceedings of the National Academy of Sciences - PNAS, 2000-11, Vol.97 (23), p.12524-12529

2000

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GCUNC-45 Is a Novel Regulator for the Progesterone Receptor/hsp90 Chaperoning Pathway

Molecular and Cellular Biology, 2006-03, Vol.26 (5), p.1722-1730

2006

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Abstract 12: A novel Hsp90 machine inhibitor combining chemotherapy and immunotherapy

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.12-12

2019

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Correction: The pleiotropic effects of TNF[alpha] in breast cancer subtypes is regulated by TNFAIP3/A20

Oncogene, 2019-07, Vol.38 (28), p.5749

2019

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The pleiotropic effects of TNF[alpha] in breast cancer subtypes is regulated by TNFAIP3/A20

Oncogene, 2019-01, Vol.38 (2), p.469

2019

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The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20

Oncogene, 2019-01, Vol.38 (4), p.469-482

2019

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The Molecular Chaperone Hsp90 Can Negatively Regulate the Activity of a Glucocorticosteroid-Dependent Promoter

Proceedings of the National Academy of Sciences - PNAS, 1999-02, Vol.96 (4), p.1439-1444

1999

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The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis

The Journal of biological chemistry, 2019-04, Vol.294 (14), p.5246-5260

2019

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Hsp90 Chaperone Activity Requires the Full-length Protein and Interaction among Its Multiple Domains

The Journal of biological chemistry, 2000-10, Vol.275 (42), p.32499-32507

2000

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Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production

Antioxidants & redox signaling, 2011-06, Vol.14 (11), p.2107-2119

2011

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Abstract 3197: Gedunin inactivates the co-chaperone p23 causing cancer cell death by apoptosis

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.3197-3197

2014

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Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model

Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade

Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti-PD-1 resistance

Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis

Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin)

Dual activity of Minnelide chemosensitize basal/triple negative breast cancer stem cells and reprograms immunosuppressive tumor microenvironment

Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity

Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms

Celastrol Inhibits Hsp90 Chaperoning of Steroid Receptors by Inducing Fibrillization of the Co-chaperone p23

The Heat Shock Protein 90 Antagonist Novobiocin Interacts with a Previously Unrecognized ATP-binding Domain in the Carboxyl Terminus of the Chaperone

The Cochaperone SGTA (Small Glutamine-rich Tetratricopeptide Repeat-containing Protein Alpha) Demonstrates Regulatory Specificity for the Androgen, Glucocorticoid, and Progesterone Receptors

Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer

HSP40 Binding Is the First Step in the HSP90 Chaperoning Pathway for the Progesterone Receptor

Analysis of Hsp90 Cochaperone Interactions Reveals a Novel Mechanism for TPR Protein Recognition

Dimerization and N-Terminal Domain Proximity Underlie the Function of the Molecular Chaperone Heat Shock Protein 90

GCUNC-45 Is a Novel Regulator for the Progesterone Receptor/hsp90 Chaperoning Pathway

Abstract 12: A novel Hsp90 machine inhibitor combining chemotherapy and immunotherapy

Correction: The pleiotropic effects of TNF[alpha] in breast cancer subtypes is regulated by TNFAIP3/A20

The pleiotropic effects of TNF[alpha] in breast cancer subtypes is regulated by TNFAIP3/A20

The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20

The Molecular Chaperone Hsp90 Can Negatively Regulate the Activity of a Glucocorticosteroid-Dependent Promoter

The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis

Hsp90 Chaperone Activity Requires the Full-length Protein and Interaction among Its Multiple Domains

Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production

Abstract 3197: Gedunin inactivates the co-chaperone p23 causing cancer cell death by apoptosis

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