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Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells

Journal of Immunology Research, 2019-01, Vol.2019, p.9678098-24

2019

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Orlistat as a FASN inhibitor and multitargeted agent for cancer therapy

Expert opinion on investigational drugs, 2018-05, Vol.27 (5), p.475-489

2018

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Severe COVID‐19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin

Journal of leukocyte biology, 2021-09, Vol.110 (3), p.425-431

2021

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An essential role for platelet-activating factor in activating mast cell migration following ultraviolet irradiation

Journal of leukocyte biology, 2014-01, Vol.95 (1), p.139-148

2014

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Valproic acid restricts mast cell activation by Listeria monocytogenes

Scientific reports, 2022-09, Vol.12 (1), p.15685-15685, Article 15685

2022

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Apoptotic Effects of N-(2-Hydroxyphenyl)-2-Propylpentanamide on U87-MG and U-2 OS Cells and Antiangiogenic Properties

Anti-cancer agents in medicinal chemistry, 2021-01, Vol.21 (11), p.1451

2021

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Cytotoxic Activity and Structure–Activity Relationship of Triazole‐Containing Bis(Aryl Ether) Macrocycles

ChemMedChem, 2018-06, Vol.13 (12), p.1193-1209

2018

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TLR2 Regulates Mast Cell IL-6 and IL-13 Production During Listeria monocytogenes Infection

Frontiers in immunology, 2021-06, Vol.12, p.650779

2021

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Does Therapeutic Repurposing in Cancer Meet the Expectations of Having Drugs at a Lower Price?

Clinical drug investigation, 2023-04, Vol.43 (4), p.227-239

2023

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The histone deacetylase inhibitor valproic acid attenuates phospholipase Cγ2 and IgE‐mediated mast cell activation

Journal of leukocyte biology, 2020-09, Vol.108 (3), p.859-866

2020

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Understanding tumor anabolism and patient catabolism in cancer-associated cachexia

American journal of cancer research, 2017-01, Vol.7 (5), p.1107-1135

2017

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The inhibitory and transcriptional effects of the epigenetic repurposed drugs hydralazine and valproate in lymphoma cells

American journal of cancer research, 2024-01, Vol.14 (6), p.3068-3082

Salamanca-Ortiz, Harold

2024

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Mast cell-derived IL-10 suppresses germinal center formation by affecting T follicular helper cell function

The Journal of immunology (1950), 2011-01, Vol.186 (1), p.25-31

2011

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Investigation of HER-2 status, treatment response and survival analysis in cervical cancer patients

European journal of gynaecological oncology, 2020-12, Vol.41 (6), p.1031

2020

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Cancer progression mediated by horizontal gene transfer in an in vivo model

PloS one, 2012-12, Vol.7 (12), p.e52754

2012

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Brucella abortus induces mast cell activation through TLR-2 and TLR-4

Microbial pathogenesis, 2023-03, Vol.176, p.106005-106005, Article 106005

2023

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Viral inhibitors of NKG2D ligands for tumor surveillance

Expert opinion on therapeutic targets, 2016-11, Vol.20 (11), p.1375-1387

2016

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Valproic acid inhibits interferon-γ production by NK cells and increases susceptibility to Listeria monocytogenes infection

Scientific reports, 2020-10, Vol.10 (1), p.17802-17802, Article 17802

2020

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[Corrigendum] A combination of inhibitors of glycolysis, glutaminolysis and de novo fatty acid synthesis decrease the expression of chemokines in human colon cancer cells

Oncology letters, 2020-03, Vol.19 (3), p.2071-2071

2020

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Valproic acid promotes a decrease in mycobacterial survival by enhancing nitric oxide production in macrophages stimulated with IFN-γ

Tuberculosis (Edinburgh, Scotland), 2019-01, Vol.114, p.123-126

2019

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N-(2-Hydroxyphenyl)-2-Propylpentanamide (HO-AAVPA) Induces Apoptosis and Cell Cycle Arrest in Breast Cancer Cells, Decreasing GPER Expression

Molecules (Basel, Switzerland), 2024-07, Vol.29 (15), p.3509

2024

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Mild C(sp3)–H functionalization of dihydrosanguinarine and dihydrochelerythrine for development of highly cytotoxic derivatives

European journal of medicinal chemistry, 2017-09, Vol.138, p.1-12

2017

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Identification of a novel germ-line mutation in the TP53 gene in a Mexican family with Li-Fraumeni syndrome

World journal of surgical oncology, 2009-12, Vol.7 (1), p.97-97, Article 97

2009

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Transcriptional changes induced by epigenetic therapy with hydralazine and magnesium valproate in cervical carcinoma

Oncology reports, 2011-02, Vol.25 (2), p.399-407

2011

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Lack in Efficacy for Imatinib Mesylate as Second-Line Treatment of Recurrent or Metastatic Cervical Cancer Expressing Platelet-Derived Growth Factor Receptor α

International journal of gynecological cancer, 2009-12, Vol.19 (9), p.1632-1637

2009

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Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells

Orlistat as a FASN inhibitor and multitargeted agent for cancer therapy

Severe COVID‐19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin

An essential role for platelet-activating factor in activating mast cell migration following ultraviolet irradiation

Valproic acid restricts mast cell activation by Listeria monocytogenes

Apoptotic Effects of N-(2-Hydroxyphenyl)-2-Propylpentanamide on U87-MG and U-2 OS Cells and Antiangiogenic Properties

Cytotoxic Activity and Structure–Activity Relationship of Triazole‐Containing Bis(Aryl Ether) Macrocycles

TLR2 Regulates Mast Cell IL-6 and IL-13 Production During Listeria monocytogenes Infection

Does Therapeutic Repurposing in Cancer Meet the Expectations of Having Drugs at a Lower Price?

The histone deacetylase inhibitor valproic acid attenuates phospholipase Cγ2 and IgE‐mediated mast cell activation

Understanding tumor anabolism and patient catabolism in cancer-associated cachexia

The inhibitory and transcriptional effects of the epigenetic repurposed drugs hydralazine and valproate in lymphoma cells

Mast cell-derived IL-10 suppresses germinal center formation by affecting T follicular helper cell function

Investigation of HER-2 status, treatment response and survival analysis in cervical cancer patients

Cancer progression mediated by horizontal gene transfer in an in vivo model

Brucella abortus induces mast cell activation through TLR-2 and TLR-4

Viral inhibitors of NKG2D ligands for tumor surveillance

Valproic acid inhibits interferon-γ production by NK cells and increases susceptibility to Listeria monocytogenes infection

[Corrigendum] A combination of inhibitors of glycolysis, glutaminolysis and de novo fatty acid synthesis decrease the expression of chemokines in human colon cancer cells

Valproic acid promotes a decrease in mycobacterial survival by enhancing nitric oxide production in macrophages stimulated with IFN-γ

N-(2-Hydroxyphenyl)-2-Propylpentanamide (HO-AAVPA) Induces Apoptosis and Cell Cycle Arrest in Breast Cancer Cells, Decreasing GPER Expression

Mild C(sp3)–H functionalization of dihydrosanguinarine and dihydrochelerythrine for development of highly cytotoxic derivatives

Identification of a novel germ-line mutation in the TP53 gene in a Mexican family with Li-Fraumeni syndrome

Transcriptional changes induced by epigenetic therapy with hydralazine and magnesium valproate in cervical carcinoma

Lack in Efficacy for Imatinib Mesylate as Second-Line Treatment of Recurrent or Metastatic Cervical Cancer Expressing Platelet-Derived Growth Factor Receptor α

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