UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Progress towards clinically useful aldosterone synthase inhibitors

Current topics in medicinal chemistry, 2013-06, Vol.13 (12), p.1385-1401

Cerny, Matthew A

2013

Volltextzugriff (PDF)

Static and Dynamic Projections of Drug-Drug Interactions Caused by Cytochrome P450 3A Time-Dependent Inhibitors Measured in Human Liver Microsomes and Hepatocytes

Drug metabolism and disposition, 2021-10, Vol.49 (10), p.947-960

2021

Volltextzugriff (PDF)

Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides

Drug metabolism and disposition, 2017-07, Vol.45 (7), p.721-733

2017

Volltextzugriff (PDF)

Prevalence of Non-Cytochrome P450-Mediated Metabolism in Food and Drug Administration-Approved Oral and Intravenous Drugs: 2006-2015

Drug metabolism and disposition, 2016-08, Vol.44 (8), p.1246-1252

Cerny, Matthew A

2016

Volltextzugriff (PDF)

Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization

Journal of medicinal chemistry, 2006-11, Vol.49 (24), p.6987-7001

2006

Volltextzugriff (PDF)

SC2.3 - Enzymology and clinical importance of reductases and hydrolases

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S2-S2

Cerny, Matthew A.

2020

Volltextzugriff (PDF)

Human Absorption, Distribution, Metabolism, and Excretion Studies: Origins, Innovations, and Importance

Drug metabolism and disposition, 2023-06, Vol.51 (6), p.647-656

2023

Volltextzugriff (PDF)

Attempting to Unmask the Inhibition of Sulfotransferase 1E1 in 17α‐Ethinyl Estradiol Drug Interactions

Journal of clinical pharmacology, 2023-08, Vol.63 (8), p.875-879

2023

Volltextzugriff (PDF)

Cytochrome P450 3A Time-Dependent Inhibition Assays Are Too Sensitive for Identification of Drugs Causing Clinically Significant Drug-Drug Interactions: A Comparison of Human Liver Microsomes and Hepatocytes and Definition of Boundaries for Inactivation Rate Constants

Drug metabolism and disposition, 2021-06, Vol.49 (6), p.442-450

2021

Volltextzugriff (PDF)

Identification of Glycochenodeoxycholate 3‐O‐Glucuronide and Glycodeoxycholate 3‐O‐Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers

Clinical pharmacology and therapeutics, 2021-03, Vol.109 (3), p.646-657

2021

Volltextzugriff (PDF)

The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Ritlecitinib, a Janus Kinase 3 and Tyrosine-Protein Kinase Family Inhibitor, in Humans

Drug metabolism and disposition, 2024-09, Vol.52 (10), p.1124

2024

Volltextzugriff (PDF)

Effective Application of Metabolite Profiling in Drug Design and Discovery

Journal of medicinal chemistry, 2020-06, Vol.63 (12), p.6387-6406

2020

Volltextzugriff (PDF)

Identification and Characterization of a Selective Human Carbonyl Reductase 1 Substrate

Drug metabolism and disposition, 2018-10, Vol.46 (10), p.1434-1440

2018

Volltextzugriff (PDF)

Hepatocyte formation, reactivity, and stability differences of acyl glucuronide and acyl coenzyme a conjugates

Drug metabolism and pharmacokinetics, 2024-04, Vol.55, p.100825, Article 100825

2024

Volltextzugriff (PDF)

Characterization of Bile Acid Sulfate Conjugates as Substrates of Human Organic Anion Transporting Polypeptides

Molecular pharmaceutics, 2023-06, Vol.20 (6), p.3020-3032

2023

Volltextzugriff (PDF)

Development of CYP11B1 and CYP11B2 assays utilizing homogenates of adrenal glands: Utility of monkey as a surrogate for human

The Journal of steroid biochemistry and molecular biology, 2015-11, Vol.154, p.197-205

2015

Volltextzugriff (PDF)

Cynomolgus monkey as a surrogate for human aldehyde oxidase metabolism of the EGFR inhibitor BIBX1382

Drug metabolism and disposition, 2014-10, Vol.42 (10), p.1751

2014

Volltextzugriff (PDF)

Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates

The Journal of pharmacology and experimental therapeutics, 2016-10, Vol.359 (1), p.142-150

2016

Volltextzugriff (PDF)

P98 - Delineation of in vitro cut-off values for CYP3A4/5 time dependent inhibition useful in early drug design – a side-by-side comparison in human liver microsomes and hepatocytes

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S52-S52

2020

Volltextzugriff (PDF)

P97 - Clinical prediction of drug-drug interaction risk due to time-dependent inhibition of cytochrome P450 3A4 - A side-by-side comparison of human liver microsome and hepatocyte

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S52-S52

2020

Volltextzugriff (PDF)

Identification of Human Sulfotransferases Involved in Lorcaserin N-Sulfamate Formation

Drug metabolism and disposition, 2016-04, Vol.44 (4), p.570-575

2016

Volltextzugriff (PDF)

Dihydrobenzisoxazole-4-one compounds are novel selective inhibitors of aldosterone synthase (CYP11B2) with in vivo activity

Bioorganic & medicinal chemistry letters, 2018-03, Vol.28 (5), p.979-984

2018

Volltextzugriff (PDF)

Cytochrome P450-Catalyzed Oxidation of N-Benzyl-N-cyclopropylamine Generates Both Cyclopropanone Hydrate and 3-Hydroxypropionaldehyde via Hydrogen Abstraction, Not Single Electron Transfer

Journal of the American Chemical Society, 2006-03, Vol.128 (10), p.3346-3354

2006

Volltextzugriff (PDF)

Identification of human UDP-glucuronosyltransferases involved in N-carbamoyl glucuronidation of lorcaserin

Drug metabolism and disposition, 2012-04, Vol.40 (4), p.772-778

2012

Volltextzugriff (PDF)

Cyclopropylamine inactivation of cytochromes P450: Role of metabolic intermediate complexes

Archives of biochemistry and biophysics, 2005-04, Vol.436 (2), p.265-275

2005

Volltextzugriff (PDF)

1 – 25 von 85

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(74)
Mit Volltextzugriff
(71)

Publikationsform

Sprache

Englisch
(85)
Japanisch
(5)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(2)
... seit 90 Tagen
(4)

Menü

Weitere Dienste

Einstellungen

Progress towards clinically useful aldosterone synthase inhibitors

Static and Dynamic Projections of Drug-Drug Interactions Caused by Cytochrome P450 3A Time-Dependent Inhibitors Measured in Human Liver Microsomes and Hepatocytes

Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides

Prevalence of Non-Cytochrome P450-Mediated Metabolism in Food and Drug Administration-Approved Oral and Intravenous Drugs: 2006-2015

Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization

SC2.3 - Enzymology and clinical importance of reductases and hydrolases

Human Absorption, Distribution, Metabolism, and Excretion Studies: Origins, Innovations, and Importance

Attempting to Unmask the Inhibition of Sulfotransferase 1E1 in 17α‐Ethinyl Estradiol Drug Interactions

Cytochrome P450 3A Time-Dependent Inhibition Assays Are Too Sensitive for Identification of Drugs Causing Clinically Significant Drug-Drug Interactions: A Comparison of Human Liver Microsomes and Hepatocytes and Definition of Boundaries for Inactivation Rate Constants

Identification of Glycochenodeoxycholate 3‐O‐Glucuronide and Glycodeoxycholate 3‐O‐Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers

The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Ritlecitinib, a Janus Kinase 3 and Tyrosine-Protein Kinase Family Inhibitor, in Humans

Effective Application of Metabolite Profiling in Drug Design and Discovery

Identification and Characterization of a Selective Human Carbonyl Reductase 1 Substrate

Hepatocyte formation, reactivity, and stability differences of acyl glucuronide and acyl coenzyme a conjugates

Characterization of Bile Acid Sulfate Conjugates as Substrates of Human Organic Anion Transporting Polypeptides

Development of CYP11B1 and CYP11B2 assays utilizing homogenates of adrenal glands: Utility of monkey as a surrogate for human

Cynomolgus monkey as a surrogate for human aldehyde oxidase metabolism of the EGFR inhibitor BIBX1382

Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates

P98 - Delineation of in vitro cut-off values for CYP3A4/5 time dependent inhibition useful in early drug design – a side-by-side comparison in human liver microsomes and hepatocytes

P97 - Clinical prediction of drug-drug interaction risk due to time-dependent inhibition of cytochrome P450 3A4 - A side-by-side comparison of human liver microsome and hepatocyte

Identification of Human Sulfotransferases Involved in Lorcaserin N-Sulfamate Formation

Dihydrobenzisoxazole-4-one compounds are novel selective inhibitors of aldosterone synthase (CYP11B2) with in vivo activity

Cytochrome P450-Catalyzed Oxidation of N-Benzyl-N-cyclopropylamine Generates Both Cyclopropanone Hydrate and 3-Hydroxypropionaldehyde via Hydrogen Abstraction, Not Single Electron Transfer

Identification of human UDP-glucuronosyltransferases involved in N-carbamoyl glucuronidation of lorcaserin

Cyclopropylamine inactivation of cytochromes P450: Role of metabolic intermediate complexes

Suchergebnisse filtern