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Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models

The Prostate, 2024-07, Vol.84 (10), p.909-921

2024

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Identification and Characterization of Small Molecule Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase

The Journal of biological chemistry, 2008-12, Vol.283 (50), p.35078-35085

2008

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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes

Wellcome open research, 2023, Vol.8, p.146-146

2023

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Novel S-Adenosylmethionine Decarboxylase Inhibitors for the Treatment of Human African Trypanosomiasis

Antimicrobial Agents and Chemotherapy, 2009-05, Vol.53 (5), p.2052-2058

2009

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Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants

Journal of medicinal chemistry, 2006-12, Vol.49 (26), p.7781-7791

2006

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Optimization of Potent Inhibitors of P. falciparum Dihydroorotate Dehydrogenase for the Treatment of Malaria

ACS medicinal chemistry letters, 2011-09, Vol.2 (9), p.708-713

2011

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Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (11), p.3049-3054

2006

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Discovery of new S-adenosylmethionine decarboxylase inhibitors for the treatment of Human African Trypanosomiasis (HAT)

Bioorganic & medicinal chemistry letters, 2009-06, Vol.19 (11), p.2916-2919

2009

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Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (1), p.228-231

2010

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Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model

The Journal of biological chemistry, 2010-10, Vol.285 (43), p.33054-33064

2010

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Studies Directed toward the Synthesis of Ulapualide A. Asymmetric Synthesis of the C26−C42 Fragment

Journal of organic chemistry, 1996-09, Vol.61 (19), p.6494-6495

1996

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Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale m agellanica 1

Journal of the American Chemical Society, 1999-06, Vol.121 (23), p.5605-5606

1999

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Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale magellanica [J. Am. Chem. Soc. 1999, 121, 5605−5606]

Journal of the American Chemical Society, 1999-09, Vol.121 (38), p.8969-8969

1999

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Identification and Characterization of Small Molecule Inhibitors of Plasmodium falciparum Dihydroorotate DehydrogenaseS

The Journal of biological chemistry, 2008-12, Vol.283 (50), p.35078-35085

2008

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Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale magellanica1

Journal of the American Chemical Society, 1999-06, Vol.121 (23), p.5605-5606

1999

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Asymmetric synthesis of a C1C19 fragment of ulapualide A

Tetrahedron letters, 2002-09, Vol.43 (39), p.7043-7046

2002

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Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale magellanica

Journal of the American Chemical Society, 1999-06, Vol.121 (23), p.5605-5606

1999

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Synthesis of the fully functionalized tris-oxazole fragment found in metabolites derived from marine organisms

Tetrahedron letters, 1997-08, Vol.38 (31), p.5445-5448

1997

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Studies directed toward the synthesis of ulapualide A: Phosphorus-based olefination as model studies for (Schlosser-like) fragment coupling

Tetrahedron letters, 1997-08, Vol.38 (31), p.5449-5452

1997

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Stereochemical assignment of the mycalolides and the ulapualides: Studies directed toward the total synthesis of ulapualide A

Celatka, Cassandra A

2005

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Asymmetric Synthesis of a C1-C19 Fragment of Ulapualide A

ChemInform, 2003-01, Vol.34 (2), p.no-no

2003

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ChemInform Abstract: Bioactive Marine Metabolites. Part 94. Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale magellanica

ChemInform, 1999-09, Vol.30 (37), p.no-no

1999

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Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models

Identification and Characterization of Small Molecule Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase

Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes

Novel S-Adenosylmethionine Decarboxylase Inhibitors for the Treatment of Human African Trypanosomiasis

Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants

Aminoindoles, a Novel Scaffold with Potent Activity against Plasmodium falciparum

Optimization of Potent Inhibitors of P. falciparum Dihydroorotate Dehydrogenase for the Treatment of Malaria

Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine

Discovery of new S-adenosylmethionine decarboxylase inhibitors for the treatment of Human African Trypanosomiasis (HAT)

Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines

Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model

Studies Directed toward the Synthesis of Ulapualide A. Asymmetric Synthesis of the C26−C42 Fragment

Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale m agellanica 1

Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale magellanica [J. Am. Chem. Soc. 1999, 121, 5605−5606]

Identification and Characterization of Small Molecule Inhibitors of Plasmodium falciparum Dihydroorotate DehydrogenaseS

Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale magellanica1

Asymmetric synthesis of a C1C19 fragment of ulapualide A

Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale magellanica

Synthesis of the fully functionalized tris-oxazole fragment found in metabolites derived from marine organisms

Studies directed toward the synthesis of ulapualide A: Phosphorus-based olefination as model studies for (Schlosser-like) fragment coupling

Stereochemical assignment of the mycalolides and the ulapualides: Studies directed toward the total synthesis of ulapualide A

Asymmetric Synthesis of a C1-C19 Fragment of Ulapualide A

ChemInform Abstract: Bioactive Marine Metabolites. Part 94. Relative and Absolute Stereochemistry of Mycalolides, Bioactive Macrolides from the Marine Sponge Mycale magellanica

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