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PERK (EIF2AK3) Regulates Proinsulin Trafficking and Quality Control in the Secretory Pathway

Diabetes (New York, N.Y.), 2010-08, Vol.59 (8), p.1937-1947

2010

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Translational control and the unfolded protein response

Antioxidants & redox signaling, 2007-12, Vol.9 (12), p.2357-2372

2007

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Brain-Specific Disruption of the eIF2α Kinase PERK Decreases ATF4 Expression and Impairs Behavioral Flexibility

Cell reports (Cambridge), 2012-06, Vol.1 (6), p.676-688

2012

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Endoplasmic Reticulum Stress Sensor Protein Kinase R–Like Endoplasmic Reticulum Kinase (PERK) Protects Against Pressure Overload–Induced Heart Failure and Lung Remodeling

Hypertension (Dallas, Tex. 1979), 2014-10, Vol.64 (4), p.738-744

2014

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Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice

PLoS genetics, 2020-04, Vol.16 (4), p.e1008693-e1008693

2020

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PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (42), p.16314-16319

2008

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PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility

PloS one, 2016-09, Vol.11 (9), p.e0162766-e0162766

2016

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PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation

Journal of cellular physiology, 2008-12, Vol.217 (3), p.693-707

2008

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The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

eLife, 2017-03, Vol.6

2017

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Giraffe genome sequence reveals clues to its unique morphology and physiology

Nature communications, 2016-05, Vol.7 (1), p.11519-11519, Article 11519

2016

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PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice

PloS one, 2009-11, Vol.4 (11), p.e8008-e8008

2009

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Hyperthermia induces the ER stress pathway

PloS one, 2011-08, Vol.6 (8), p.e23740-e23740

2011

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PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis

Biochemical journal, 2006-01, Vol.393 (Pt 1), p.201-209

2006

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Perk gene dosage regulates glucose homeostasis by modulating pancreatic β-cell functions

PloS one, 2014-06, Vol.9 (6), p.e99684-e99684

2014

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Seeing spots: quantifying mother-offspring similarity and assessing fitness consequences of coat pattern traits in a wild population of giraffes ( Giraffa camelopardalis )

PeerJ (San Francisco, CA), 2018-10, Vol.6, p.e5690-e5690, Article e5690

2018

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GCN2 Protein Kinase Is Required to Activate Amino Acid Deprivation Responses in Mice Treated with the Anti-cancer Agent l-Asparaginase

The Journal of biological chemistry, 2009-11, Vol.284 (47), p.32742-32749

2009

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Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits

Nature neuroscience, 2013-09, Vol.16 (9), p.1299-1305

2013

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The PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas

Molecular and Cellular Biology, 2002-06, Vol.22 (11), p.3864-3874

2002

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Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response

Molecular and Cellular Biology, 2004-02, Vol.24 (3), p.1365-1377

2004

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Genetic connectivity and population structure of African savanna elephants (Loxodonta africana) in Tanzania

Ecology and evolution, 2020-10, Vol.10 (20), p.11069-11089

2020

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25-Hydroxycholesterol Activates the Integrated Stress Response to Reprogram Transcription and Translation in Macrophages

The Journal of biological chemistry, 2013-12, Vol.288 (50), p.35812-35823

2013

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Uncharged tRNA and Sensing of Amino Acid Deficiency in Mammalian Piriform Cortex

Science (American Association for the Advancement of Science), 2005-03, Vol.307 (5716), p.1776-1778

2005

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GCN2 regulates the CCAAT enhancer binding protein beta and hepatic gluconeogenesis

American journal of physiology: endocrinology and metabolism, 2013-10, Vol.305 (8), p.E1007-E1017

2013

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Preservation of Liver Protein Synthesis during Dietary Leucine Deprivation Occurs at the Expense of Skeletal Muscle Mass in Mice Deleted for eIF2 Kinase GCN2

The Journal of biological chemistry, 2004-08, Vol.279 (35), p.36553-36561

2004

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Evolutionary analysis of vision genes identifies potential drivers of visual differences between giraffe and okapi

PeerJ (San Francisco, CA), 2017-04, Vol.5, p.e3145-e3145, Article e3145

2017

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PERK (EIF2AK3) Regulates Proinsulin Trafficking and Quality Control in the Secretory Pathway

Translational control and the unfolded protein response

Brain-Specific Disruption of the eIF2α Kinase PERK Decreases ATF4 Expression and Impairs Behavioral Flexibility

Endoplasmic Reticulum Stress Sensor Protein Kinase R–Like Endoplasmic Reticulum Kinase (PERK) Protects Against Pressure Overload–Induced Heart Failure and Lung Remodeling

Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice

PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation

PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility

PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation

The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

Giraffe genome sequence reveals clues to its unique morphology and physiology

PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice

Hyperthermia induces the ER stress pathway

PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis

Perk gene dosage regulates glucose homeostasis by modulating pancreatic β-cell functions

Seeing spots: quantifying mother-offspring similarity and assessing fitness consequences of coat pattern traits in a wild population of giraffes ( Giraffa camelopardalis )

GCN2 Protein Kinase Is Required to Activate Amino Acid Deprivation Responses in Mice Treated with the Anti-cancer Agent l-Asparaginase

Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits

The PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas

Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response

Genetic connectivity and population structure of African savanna elephants (Loxodonta africana) in Tanzania

25-Hydroxycholesterol Activates the Integrated Stress Response to Reprogram Transcription and Translation in Macrophages

Uncharged tRNA and Sensing of Amino Acid Deficiency in Mammalian Piriform Cortex

GCN2 regulates the CCAAT enhancer binding protein beta and hepatic gluconeogenesis

Preservation of Liver Protein Synthesis during Dietary Leucine Deprivation Occurs at the Expense of Skeletal Muscle Mass in Mice Deleted for eIF2 Kinase GCN2

Evolutionary analysis of vision genes identifies potential drivers of visual differences between giraffe and okapi

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