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Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance

Current cancer drug targets, 2012-03, Vol.12 (3), p.197

2012

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EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway

Oncogene, 2012-09, Vol.31 (36), p.4054-4066

2012

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EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180

Oncogene, 2014-05, Vol.33 (19), p.2504-2512

2014

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IGFBP2 potentiates nuclear EGFR-STAT3 signaling

Oncogene, 2016-02, Vol.35 (6), p.738-747

2016

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EGFRvIII promotes glioma angiogenesis and growth through the NF-[kappa]B, interleukin-8 pathway

Oncogene, 2012-09, Vol.31 (36), p.4054

2012

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Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling

Oncogene, 2015-07, Vol.34 (31), p.4078-4088

2015

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Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo

Cancer research (Chicago, Ill.), 2000-02, Vol.60 (4), p.847-853

2000

Volltextzugriff (PDF)

Disruption of Forkhead Transcription Factor (FOXO) Family Members in Mice Reveals Their Functional Diversification

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.2975-2980

2004

Volltextzugriff (PDF)

The WHO Classification of Tumors of the Nervous System

Journal of neuropathology and experimental neurology, 2002-03, Vol.61 (3), p.215-225

2002

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A Global Transcriptional Regulatory Role for c-Myc in Burkitt's Lymphoma Cells

Proceedings of the National Academy of Sciences - PNAS, 2003-07, Vol.100 (14), p.8164-8169

2003

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The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells

Cancer research (Chicago, Ill.), 1998-11, Vol.58 (22), p.5002-5008

1998

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Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1

Nature genetics, 2002-10, Vol.32 (2), p.245-253

2002

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Methylation-associated silencing of the tissue inhibitor of Metalloproteinase-3 gene suggests a suppressor role in kidney, brain, and other human cancers

Cancer research (Chicago, Ill.), 1999-02, Vol.59 (4), p.798-802

1999

Volltextzugriff (PDF)

Protein Kinase B/Akt-Mediated Phosphorylation Promotes Nuclear Exclusion of the Winged Helix Transcription Factor FKHR1

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (13), p.7421-7426

1999

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A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis

Cancer research (Chicago, Ill.), 1996-11, Vol.56 (21), p.5079-5086

1996

Volltextzugriff (PDF)

Malignant glioma: genetics and biology of a grave matter

Genes & development, 2001-06, Vol.15 (11), p.1311-1333

2001

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D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability

Cancer research (Chicago, Ill.), 1999-05, Vol.59 (10), p.2297-2301

1999

Volltextzugriff (PDF)

The potential of TRAIL for cancer chemotherapy

Apoptosis (London), 2001-06, Vol.6 (3), p.191

2001

Volltextzugriff (PDF)

Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase

Cancer research (Chicago, Ill.), 1999-04, Vol.59 (7), p.1464-1472

1999

Volltextzugriff (PDF)

Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily

Genomics (San Diego, Calif.), 1998-01, Vol.47 (2), p.187-199

1998

Volltextzugriff (PDF)

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns

Nature genetics, 2000-02, Vol.24 (2), p.132-138

2000

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Intratumoral heterogeneity of ADAM23 promotes tumor growth and metastasis through LGI4 and nitric oxide signals

Oncogene, 2015-03, Vol.34 (10), p.1270-1279

2015

Volltextzugriff (PDF)

Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation

Cancer research (Chicago, Ill.), 1996-05, Vol.56 (10), p.2405-2410

1996

Volltextzugriff (PDF)

A Mutant Epidermal Growth Factor Receptor Common in Human Glioma Confers Enhanced Tumorigenicity

Proceedings of the National Academy of Sciences - PNAS, 1994-08, Vol.91 (16), p.7727-7731

1994

Volltextzugriff (PDF)

PTEN gene transfer in human malignant glioma : sensitization to irradiation and CD95L-induced apoptosis

Oncogene, 1999-07, Vol.18 (27), p.3936-3943

1999

Volltextzugriff (PDF)

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Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance

EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway

EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180

IGFBP2 potentiates nuclear EGFR-STAT3 signaling

EGFRvIII promotes glioma angiogenesis and growth through the NF-[kappa]B, interleukin-8 pathway

Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo

Disruption of Forkhead Transcription Factor (FOXO) Family Members in Mice Reveals Their Functional Diversification

The WHO Classification of Tumors of the Nervous System

A Global Transcriptional Regulatory Role for c-Myc in Burkitt's Lymphoma Cells

The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells

Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1

Methylation-associated silencing of the tissue inhibitor of Metalloproteinase-3 gene suggests a suppressor role in kidney, brain, and other human cancers

Protein Kinase B/Akt-Mediated Phosphorylation Promotes Nuclear Exclusion of the Winged Helix Transcription Factor FKHR1

A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis

Malignant glioma: genetics and biology of a grave matter

D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability

The potential of TRAIL for cancer chemotherapy

Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase

Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns

Intratumoral heterogeneity of ADAM23 promotes tumor growth and metastasis through LGI4 and nitric oxide signals

Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation

A Mutant Epidermal Growth Factor Receptor Common in Human Glioma Confers Enhanced Tumorigenicity

PTEN gene transfer in human malignant glioma : sensitization to irradiation and CD95L-induced apoptosis

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