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Genotoxic metabolites of estradiol in breast: potential mechanism of estradiol induced carcinogenesis

Journal of steroid biochemistry and molecular biology, 2003-09, Vol.86 (3), p.477-486

2003

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Molecular Origin of Cancer: Catechol Estrogen-3,4-Quinones as Endogenous Tumor Initiators

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (20), p.10937-10942

1997

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Initiation of cancer and other diseases by catechol ortho-quinones: a unifying mechanism

Cellular and molecular life sciences : CMLS, 2002-04, Vol.59 (4), p.665-681

2002

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Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons

Xenobiotica, 1995, Vol.25 (7), p.677-688

1995

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Spectral Characterization of Catechol Estrogen Quinone (CEQ)-Derived DNA Adducts and Their Identification in Human Breast Tissue Extract

Chemical research in toxicology, 2003-09, Vol.16 (9), p.1107-1117

2003

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Potential biomarker for early risk assessment of prostate cancer

The Prostate, 2006-10, Vol.66 (14), p.1565-1571

2006

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Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2- and 4-hydroxylation of 17β-estradiol in female Sprague-Dawley rats

Carcinogenesis (New York), 2000-08, Vol.21 (8), p.1593-1599

2000

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Relating Aromatic Hydrocarbon-Induced DNA Adducts and c-H-ras Mutations in Mouse Skin Papillomas: The Role of Apurinic Sites

Proceedings of the National Academy of Sciences - PNAS, 1995-10, Vol.92 (22), p.10422-10426

1995

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Imbalance of Estrogen Homeostasis in Kidney and Liver of Hamsters Treated with Estradiol: Implications for Estrogen-Induced Initiation of Renal Tumors

Chemical research in toxicology, 2001-08, Vol.14 (8), p.1041-1050

2001

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Development of Monoclonal Antibodies to 4-Hydroxyestrogen-2-N-Acetylcysteine Conjugates: Immunoaffinity and Spectroscopic Studies

Chemical research in toxicology, 2005-10, Vol.18 (10), p.1520-1527

2005

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Detection and Quantification of Depurinated Benzo[a]pyrene-Adducted DNA Bases in the Urine of Cigarette Smokers and Women Exposed to Household Coal Smoke

Chemical research in toxicology, 2001-02, Vol.14 (2), p.192-201

2001

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Identification and Quantitation of Dibenzo[a,l]pyrene-DNA Adducts Formed by Rat Liver Microsomes in Vitro: Preponderance of Depurinating Adducts

Biochemistry (Easton), 1995-06, Vol.34 (25), p.8043-8049

1995

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The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation

Pharmacology & therapeutics (Oxford), 1992, Vol.55 (2), p.183-199

1992

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Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene

Oncogene, 2001-11, Vol.20 (55), p.7945-7953

2001

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Detection of dibenzo[a, l]pyrene-induced H-ras codon 61 mutant genes in preneoplastic SENCAR mouse skin using a new PCR-RFLP method

Oncogene, 1998-06, Vol.16 (24), p.3203-3210

1998

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Synthesis and tumor-initiating activity in mouse skin of dibenzo[a,l]pyrene syn- and anti-fjord-region diolepoxides

Carcinogenesis (New York), 1994-11, Vol.15 (11), p.2455-2460

1994

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Identification and quantitation of benzo[a]pyrene-DNA adducts formed in mouse skin

Chemical research in toxicology, 1993-05, Vol.6 (3), p.356-363

1993

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Identification and quantitation of benzo[a]pyrene-DNA adducts formed by rat liver microsomes in vitro

Chemical research in toxicology, 1992-03, Vol.5 (2), p.302-309

1992

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Molecular Characteristics of Catechol Estrogen Quinones in Reactions with Deoxyribonucleosides

Chemical research in toxicology, 1996-07, Vol.9 (5), p.851-859

1996

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Model adducts of benzo[a]pyrene and nucleosides formed from its radical cation and diol epoxide

Chemical research in toxicology, 1992-03, Vol.5 (2), p.293-302

1992

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Mechanism of metabolic activation of the potent carcinogen 7,12-dimethylbenz[a]anthracene

Chemical research in toxicology, 1992-03, Vol.5 (2), p.220-226

1992

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Identification and quantitation of 7,12-dimethylbenz[a]anthracene-DNA adducts formed in mouse skin

Chemical research in toxicology, 1993-05, Vol.6 (3), p.364-371

1993

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Binding of benzo[a]pyrene to DNA by cytochrome P 450 catalyzed one-electron oxidation in rat liver microsomes and nuclei

Biochemistry (Easton), 1990-05, Vol.29 (20), p.4820-4827

1990

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Catechol estrogen conjugates and DNA adducts in the kidney of male Syrian golden hamsters treated with 4-hydroxyestradiol: potential biomarkers for estrogen-initiated cancer

Carcinogenesis (New York), 2001-03, Vol.22 (3), p.489-497

2001

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Formation of 8-methylguanine as a result of DNA alkylation by methyl radicals generated during horseradish peroxidase-catalyzed oxidation of methylhydrazine

The Journal of biological chemistry, 1990-12, Vol.265 (36), p.22093-22096

1990

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Genotoxic metabolites of estradiol in breast: potential mechanism of estradiol induced carcinogenesis

Molecular Origin of Cancer: Catechol Estrogen-3,4-Quinones as Endogenous Tumor Initiators

Initiation of cancer and other diseases by catechol ortho-quinones: a unifying mechanism

Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons

Spectral Characterization of Catechol Estrogen Quinone (CEQ)-Derived DNA Adducts and Their Identification in Human Breast Tissue Extract

Potential biomarker for early risk assessment of prostate cancer

Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2- and 4-hydroxylation of 17β-estradiol in female Sprague-Dawley rats

Relating Aromatic Hydrocarbon-Induced DNA Adducts and c-H-ras Mutations in Mouse Skin Papillomas: The Role of Apurinic Sites

Imbalance of Estrogen Homeostasis in Kidney and Liver of Hamsters Treated with Estradiol: Implications for Estrogen-Induced Initiation of Renal Tumors

Development of Monoclonal Antibodies to 4-Hydroxyestrogen-2-N-Acetylcysteine Conjugates: Immunoaffinity and Spectroscopic Studies

Detection and Quantification of Depurinated Benzo[a]pyrene-Adducted DNA Bases in the Urine of Cigarette Smokers and Women Exposed to Household Coal Smoke

Identification and Quantitation of Dibenzo[a,l]pyrene-DNA Adducts Formed by Rat Liver Microsomes in Vitro: Preponderance of Depurinating Adducts

The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation

Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene

Detection of dibenzo[a, l]pyrene-induced H-ras codon 61 mutant genes in preneoplastic SENCAR mouse skin using a new PCR-RFLP method

Synthesis and tumor-initiating activity in mouse skin of dibenzo[a,l]pyrene syn- and anti-fjord-region diolepoxides

Identification and quantitation of benzo[a]pyrene-DNA adducts formed in mouse skin

Identification and quantitation of benzo[a]pyrene-DNA adducts formed by rat liver microsomes in vitro

Molecular Characteristics of Catechol Estrogen Quinones in Reactions with Deoxyribonucleosides

Model adducts of benzo[a]pyrene and nucleosides formed from its radical cation and diol epoxide

Mechanism of metabolic activation of the potent carcinogen 7,12-dimethylbenz[a]anthracene

Identification and quantitation of 7,12-dimethylbenz[a]anthracene-DNA adducts formed in mouse skin

Binding of benzo[a]pyrene to DNA by cytochrome P 450 catalyzed one-electron oxidation in rat liver microsomes and nuclei

Catechol estrogen conjugates and DNA adducts in the kidney of male Syrian golden hamsters treated with 4-hydroxyestradiol: potential biomarkers for estrogen-initiated cancer

Formation of 8-methylguanine as a result of DNA alkylation by methyl radicals generated during horseradish peroxidase-catalyzed oxidation of methylhydrazine

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