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N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

Nature communications, 2020-05, Vol.11 (1), p.2212-2212, Article 2212

2020

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Neutrophils: New insights and open questions

Science immunology, , Vol.3 (30)

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Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells

Kidney international, 2016-04, Vol.89 (4), p.862-873

2016

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Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A

The Journal of biological chemistry, 2017-06, Vol.292 (25), p.10328-10346

2017

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Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein

Molecular biology of the cell, 2012-05, Vol.23 (10), p.1902-1916

2012

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Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiency

PLoS genetics, 2014-06, Vol.10 (6), p.e1004409-e1004409

2014

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Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency

Autophagy, 2019-10, Vol.15 (10), p.1738-1756

2019

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Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis

Kidney international, 2019-08, Vol.96 (2), p.350-362

2019

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Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation

Cell reports (Cambridge), 2020-06, Vol.31 (9), p.107721-107721, Article 107721

2020

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Impairment of chaperone‐mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

EMBO molecular medicine, 2015-02, Vol.7 (2), p.158-174

2015

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Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation

Nature communications, 2022-09, Vol.13 (1), p.5529-5529, Article 5529

2022

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Upregulation of the Rab27a-Dependent Trafficking and Secretory Mechanisms Improves Lysosomal Transport, Alleviates Endoplasmic Reticulum Stress, and Reduces Lysosome Overload in Cystinosis

Molecular and Cellular Biology, 2013-08, Vol.33 (15), p.2950-2962

2013

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Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13‐4 in mast cell secretion

The FEBS journal, 2013-02, Vol.280 (3), p.892-903

2013

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Molecular mechanisms regulating secretory organelles and endosomes in neutrophils and their implications for inflammation

Immunological reviews, 2016-09, Vol.273 (1), p.249-265

2016

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Increased Survival and Reduced Neutrophil Infiltration of the Liver in Rab27a- but Not Munc13-4-Deficient Mice in Lipopolysaccharide-Induced Systemic Inflammation

Infection and Immunity, 2011-09, Vol.79 (9), p.3607-3618

2011

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Human CD79b + neutrophils in the blood are associated with early-stage melanoma

Frontiers in immunology, 2023, Vol.14, p.1224045-1224045

2023

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Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells

Frontiers in endocrinology (Lausanne), 2019-02, Vol.10, p.21-21

2019

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Rab27a and Rab27b Regulate Neutrophil Azurophilic Granule Exocytosis and NADPH oxidase Activity by Independent Mechanisms

Traffic (Copenhagen, Denmark), 2010-04, Vol.11 (4), p.533-547

2010

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Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes

Biochemical journal, 2007-03, Vol.402 (2), p.229-239

2007

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Munc13-4 Restricts Motility of Rab27a-expressing Vesicles to Facilitate Lipopolysaccharide-induced Priming of Exocytosis in Neutrophils

The Journal of biological chemistry, 2011-02, Vol.286 (7), p.5647-5656

2011

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Increased Neutrophil Secretion Induced by NLRP3 Mutation Links the Inflammasome to Azurophilic Granule Exocytosis

Frontiers in cellular and infection microbiology, 2017-12, Vol.7, p.507-507

2017

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The role of Rab27a in the regulation of neutrophil function

Cellular microbiology, 2014-09, Vol.16 (9), p.1301-1310

Catz, Sergio D.

2014

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Cross-talk between IRAK-4 and the NADPH oxidase

Biochemical journal, 2007-05, Vol.403 (3), p.451-461

2007

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Therapeutic targeting of neutrophil exocytosis

Journal of leukocyte biology, 2020-03, Vol.107 (3), p.393-408

2020

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Editorial: The secrets of secretion

Journal of leukocyte biology, 2017-07, Vol.102 (1), p.4-6

Catz, Sergio D.

2017

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N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

Neutrophils: New insights and open questions

Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells

Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A

Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein

Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiency

Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency

Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis

Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation

Impairment of chaperone‐mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation

Upregulation of the Rab27a-Dependent Trafficking and Secretory Mechanisms Improves Lysosomal Transport, Alleviates Endoplasmic Reticulum Stress, and Reduces Lysosome Overload in Cystinosis

Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13‐4 in mast cell secretion

Molecular mechanisms regulating secretory organelles and endosomes in neutrophils and their implications for inflammation

Increased Survival and Reduced Neutrophil Infiltration of the Liver in Rab27a- but Not Munc13-4-Deficient Mice in Lipopolysaccharide-Induced Systemic Inflammation

Human CD79b + neutrophils in the blood are associated with early-stage melanoma

Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells

Rab27a and Rab27b Regulate Neutrophil Azurophilic Granule Exocytosis and NADPH oxidase Activity by Independent Mechanisms

Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes

Munc13-4 Restricts Motility of Rab27a-expressing Vesicles to Facilitate Lipopolysaccharide-induced Priming of Exocytosis in Neutrophils

Increased Neutrophil Secretion Induced by NLRP3 Mutation Links the Inflammasome to Azurophilic Granule Exocytosis

The role of Rab27a in the regulation of neutrophil function

Cross-talk between IRAK-4 and the NADPH oxidase

Therapeutic targeting of neutrophil exocytosis

Editorial: The secrets of secretion

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