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The pathogenesis of systemic lupus erythematosus: Harnessing big data to understand the molecular basis of lupus

Journal of autoimmunity, 2020-06, Vol.110, p.102359-102359, Article 102359

2020

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Identification of alterations in macrophage activation associated with disease activity in systemic lupus erythematosus

PloS one, 2018-12, Vol.13 (12), p.e0208132-e0208132

2018

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Altered expression of genes controlling metabolism characterizes the tissue response to immune injury in lupus

Scientific reports, 2021-07, Vol.11 (1), p.14789-18, Article 14789

2021

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Analysis of Trans-Ancestral SLE Risk Loci Identifies Unique Biologic Networks and Drug Targets in African and European Ancestries

American journal of human genetics, 2020-11, Vol.107 (5), p.864-881

2020

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Analysis of transcriptomic features reveals molecular endotypes of SLE with clinical implications

Genome medicine, 2023-10, Vol.15 (1), p.84-84, Article 84

2023

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Publisher Correction: Analysis of transcriptomic features reveals molecular endotypes of SLE with clinical implications

Genome medicine, 2023-12, Vol.15 (1), p.113-113, Article 113

2023

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Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases

Frontiers in immunology, 2019-09, Vol.10, p.2136-2136

2019

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Selective Histone Deacetylase 6 Inhibition Normalizes B Cell Activation and Germinal Center Formation in a Model of Systemic Lupus Erythematosus

Frontiers in immunology, 2019-10, Vol.10, p.2512-2512

2019

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Transcriptome and IgH Repertoire Analyses Show That CD11chi B Cells Are a Distinct Population With Similarity to B Cells Arising in Autoimmunity and Infection

Frontiers in immunology, 2021-03, Vol.12, p.649458-649458

2021

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Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications for Pathogenic Mechanism and Drug Targeting

Genes, 2021-11, Vol.12 (12), p.1898

2021

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Preclinical Evidence for the Glucocorticoid-Sparing Potential of a Dual Toll-Like Receptor 7/8 Inhibitor in Autoimmune Diseases

The Journal of pharmacology and experimental therapeutics, 2024-03, Vol.388 (3), p.751-764

2024

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Genomic Identification of Low-Density Granulocytes and Analysis of Their Role in the Pathogenesis of Systemic Lupus Erythematosus

The Journal of immunology (1950), 2019-06, Vol.202 (11), p.3309-3317

2019

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Machine learning approaches to predict lupus disease activity from gene expression data

Scientific reports, 2019-07, Vol.9 (1), p.9617-12, Article 9617

2019

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A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (ITP)

British journal of haematology, 2018-11, Vol.183 (3), p.501-503

2018

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Gene expression analysis delineates the potential roles of multiple interferons in systemic lupus erythematosus

Communications biology, 2019-04, Vol.2 (1), p.140, Article 140

2019

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Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus

JCI insight, 2020-08, Vol.5 (15)

2020

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Analysis of gene expression from systemic lupus erythematosus synovium reveals myeloid cell-driven pathogenesis of lupus arthritis

Scientific reports, 2020-10, Vol.10 (1), p.17361-17361, Article 17361

2020

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2101 Gene Expression Profiling of Key Immune/Inflammatory Pathways Reveals Molecular Endotypes of SLE with Clinical Implications

Lupus science & medicine, 2022-12, Vol.9 (Suppl 3), p.A107-A108

2022

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Role of Specific CD8+ T Cells in the Severity of a Fulminant Zoonotic Viral Hemorrhagic Fever, Hantavirus Pulmonary Syndrome

The Journal of immunology (1950), 2004-03, Vol.172 (5), p.3297-3304

2004

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304 Metabolic dysregulation characterizes the tissue response to immune injury in systemic lupus erythematosus and inflammatory skin diseases

Lupus science & medicine, 2021-11, Vol.8 (Suppl 2), p.A8-A9

2021

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Differential Evolution and Stability of Epitope-Specific CD8+ T Cell Responses in EBV Infection

The Journal of immunology (1950), 2001-10, Vol.167 (8), p.4450-4457

2001

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Phenotypic and Functional Heterogeneity of EBV Epitope-Specific CD8+ T Cells

The Journal of immunology (1950), 2002-04, Vol.168 (8), p.4184-4191

2002

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Infrequent Detection of HIV-1-Specific, But Not Cytomegalovirus-Specific, CD8+ T Cell Responses in Young HIV-1-Infected Infants

The Journal of immunology (1950), 2001-12, Vol.167 (12), p.7134-7140

2001

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The route of antigen entry determines the requirement for L-selectin during immune responses

The Journal of experimental medicine, 1996-12, Vol.184 (6), p.2341-2351

1996

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Novel targeted therapies for African-American and European-American SLE patients identified from E-Genes elucidated by transancestral SNP mapping

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.175-175.21

2018

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The pathogenesis of systemic lupus erythematosus: Harnessing big data to understand the molecular basis of lupus

Identification of alterations in macrophage activation associated with disease activity in systemic lupus erythematosus

Altered expression of genes controlling metabolism characterizes the tissue response to immune injury in lupus

Analysis of Trans-Ancestral SLE Risk Loci Identifies Unique Biologic Networks and Drug Targets in African and European Ancestries

Analysis of transcriptomic features reveals molecular endotypes of SLE with clinical implications

Publisher Correction: Analysis of transcriptomic features reveals molecular endotypes of SLE with clinical implications

Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases

Selective Histone Deacetylase 6 Inhibition Normalizes B Cell Activation and Germinal Center Formation in a Model of Systemic Lupus Erythematosus

Transcriptome and IgH Repertoire Analyses Show That CD11chi B Cells Are a Distinct Population With Similarity to B Cells Arising in Autoimmunity and Infection

Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications for Pathogenic Mechanism and Drug Targeting

Preclinical Evidence for the Glucocorticoid-Sparing Potential of a Dual Toll-Like Receptor 7/8 Inhibitor in Autoimmune Diseases

Genomic Identification of Low-Density Granulocytes and Analysis of Their Role in the Pathogenesis of Systemic Lupus Erythematosus

Machine learning approaches to predict lupus disease activity from gene expression data

A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (ITP)

Gene expression analysis delineates the potential roles of multiple interferons in systemic lupus erythematosus

Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus

Analysis of gene expression from systemic lupus erythematosus synovium reveals myeloid cell-driven pathogenesis of lupus arthritis

2101 Gene Expression Profiling of Key Immune/Inflammatory Pathways Reveals Molecular Endotypes of SLE with Clinical Implications

Role of Specific CD8+ T Cells in the Severity of a Fulminant Zoonotic Viral Hemorrhagic Fever, Hantavirus Pulmonary Syndrome

304 Metabolic dysregulation characterizes the tissue response to immune injury in systemic lupus erythematosus and inflammatory skin diseases

Differential Evolution and Stability of Epitope-Specific CD8+ T Cell Responses in EBV Infection

Phenotypic and Functional Heterogeneity of EBV Epitope-Specific CD8+ T Cells

Infrequent Detection of HIV-1-Specific, But Not Cytomegalovirus-Specific, CD8+ T Cell Responses in Young HIV-1-Infected Infants

The route of antigen entry determines the requirement for L-selectin during immune responses

Novel targeted therapies for African-American and European-American SLE patients identified from E-Genes elucidated by transancestral SNP mapping

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