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The Microbiota-Derived Metabolite of Quercetin, 3,4-Dihydroxyphenylacetic Acid Prevents Malignant Transformation and Mitochondrial Dysfunction Induced by Hemin in Colon Cancer and Normal Colon Epithelia Cell Lines

Molecules (Basel, Switzerland), 2020-09, Vol.25 (18), p.4138

2020

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Medicinal Chemistry Targeting Mitochondria: From New Vehicles and Pharmacophore Groups to Old Drugs with Mitochondrial Activity

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8684

2020

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FoxO1 is required for high glucose-dependent cardiac fibroblasts into myofibroblast phenoconversion

Cellular signalling, 2021-07, Vol.83, p.109978-109978, Article 109978

2021

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Lipoxin A4 prevents high glucose-induced inflammatory response in cardiac fibroblast through FOXO1 inhibition

Cellular signalling, 2023-06, Vol.106, p.110657-110657, Article 110657

2023

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Antimigratory Effect of Lipophilic Cations Derived from Gallic and Gentisic Acid and Synergistic Effect with 5-Fluorouracil on Metastatic Colorectal Cancer Cells: A New Synthesis Route

Cancers, 2024-08, Vol.16 (17), p.2980

2024

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Statins change the cytokine profile in Trypanosoma cruzi -infected U937 macrophages and murine cardiac tissue through Rho-associated kinases inhibition

Frontiers in immunology, 2023-01, Vol.13, p.1035589-1035589

2023

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Gallic acid triphenylphosphonium derivatives TPP+-C10 and TPP+-C12 inhibit mitochondrial function in Candida albicans exerting antifungal and antibiofilm effects

Journal of applied microbiology, 2024-01, Vol.135 (1)

2024

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Kaempferol Induces Cell Death and Sensitizes Human Head and Neck Squamous Cell Carcinoma Cell Lines to Cisplatin

Cell Biology and Translational Medicine, Volume 12, 2021-01, Vol.1326, p.95-109

2021

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Novel benzoate-lipophilic cations selectively induce cell death in human colorectal cancer cell lines

Toxicology in vitro, 2020-06, Vol.65, p.104814-104814, Article 104814

2020

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TGF-β1 prevents simulated ischemia/reperfusion-induced cardiac fibroblast apoptosis by activation of both canonical and non-canonical signaling pathways

Biochimica et biophysica acta, 2013-06, Vol.1832 (6), p.754-762

2013

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Complex Mitochondrial Dysfunction Induced by TPP + -Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells

Cells (Basel, Switzerland), 2020-02, Vol.9 (2), p.407

2020

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EPAC expression and function in cardiac fibroblasts and myofibroblasts

Toxicology and applied pharmacology, 2013-10, Vol.272 (2), p.414-422

2013

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Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs

Toxicology in vitro, 2019-02, Vol.54, p.375-390

2019

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Destabilization of mitochondrial functions as a target against breast cancer progression: Role of TPP+-linked-polyhydroxybenzoates

Toxicology and applied pharmacology, 2016-10, Vol.309, p.2-14

2016

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Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts

Toxicology and applied pharmacology, 2011-08, Vol.255 (1), p.57-64

2011

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Continuous flow synthesis of lipophilic cations derived from benzoic acid as new cytotoxic chemical entities in human head and neck carcinoma cell lines

RSC medicinal chemistry, 2020-10, Vol.11 (1), p.121-1225

2020

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Electrochemistry of interaction of 2-(2-nitrophenyl)-benzimidazole derivatives with DNA

Bioelectrochemistry (Amsterdam, Netherlands), 2010-10, Vol.79 (2), p.162-167

2010

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Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability

Toxicology (Amsterdam), 2012-03, Vol.294 (1), p.42-49

2012

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Differential regulation of collagen secretion by kinin receptors in cardiac fibroblast and myofibroblast

Toxicology and applied pharmacology, 2012-06, Vol.261 (3), p.300-308

2012

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Cardiac fibroblast death by ischemia/reperfusion is partially inhibited by IGF-1 through both PI3K/Akt and MEK–ERK pathways

Experimental and molecular pathology, 2012-08, Vol.93 (1), p.1-7

2012

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SGK1 is necessary to FoxO3a negative regulation, oxidative stress and cardiac fibroblast activation induced by TGF-β1

Cellular signalling, 2023-09, Vol.109, p.110778-110778, Article 110778

2023

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Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-β1

Biochimica et biophysica acta. Molecular cell research, 2020-07, Vol.1867 (7), p.118695-118695, Article 118695

2020

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Pharmacological Effects of Caffeic Acid and Its Derivatives in Cancer: New Targeted Compounds for the Mitochondria

Cell Biology and Translational Medicine, Volume 17, 2022, Vol.1401, p.213-225

2022

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TGF-β1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts

Molecular biology reports, 2019-10, Vol.46 (5), p.5197-5207

2019

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Safety and Pharmacokinetics of a Combined Antioxidant Therapy against Myocardial Reperfusion Injury: A Phase 1 Randomized Clinical Trial in Healthy Humans

Clinical pharmacology in drug development, 2024-09, Vol.13 (9), p.1051-1060

2024

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The Microbiota-Derived Metabolite of Quercetin, 3,4-Dihydroxyphenylacetic Acid Prevents Malignant Transformation and Mitochondrial Dysfunction Induced by Hemin in Colon Cancer and Normal Colon Epithelia Cell Lines

Medicinal Chemistry Targeting Mitochondria: From New Vehicles and Pharmacophore Groups to Old Drugs with Mitochondrial Activity

FoxO1 is required for high glucose-dependent cardiac fibroblasts into myofibroblast phenoconversion

Lipoxin A4 prevents high glucose-induced inflammatory response in cardiac fibroblast through FOXO1 inhibition

Antimigratory Effect of Lipophilic Cations Derived from Gallic and Gentisic Acid and Synergistic Effect with 5-Fluorouracil on Metastatic Colorectal Cancer Cells: A New Synthesis Route

Statins change the cytokine profile in Trypanosoma cruzi -infected U937 macrophages and murine cardiac tissue through Rho-associated kinases inhibition

Gallic acid triphenylphosphonium derivatives TPP+-C10 and TPP+-C12 inhibit mitochondrial function in Candida albicans exerting antifungal and antibiofilm effects

Kaempferol Induces Cell Death and Sensitizes Human Head and Neck Squamous Cell Carcinoma Cell Lines to Cisplatin

Novel benzoate-lipophilic cations selectively induce cell death in human colorectal cancer cell lines

TGF-β1 prevents simulated ischemia/reperfusion-induced cardiac fibroblast apoptosis by activation of both canonical and non-canonical signaling pathways

Complex Mitochondrial Dysfunction Induced by TPP + -Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells

EPAC expression and function in cardiac fibroblasts and myofibroblasts

Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs

Destabilization of mitochondrial functions as a target against breast cancer progression: Role of TPP+-linked-polyhydroxybenzoates

Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts

Continuous flow synthesis of lipophilic cations derived from benzoic acid as new cytotoxic chemical entities in human head and neck carcinoma cell lines

Electrochemistry of interaction of 2-(2-nitrophenyl)-benzimidazole derivatives with DNA

Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability

Differential regulation of collagen secretion by kinin receptors in cardiac fibroblast and myofibroblast

Cardiac fibroblast death by ischemia/reperfusion is partially inhibited by IGF-1 through both PI3K/Akt and MEK–ERK pathways

SGK1 is necessary to FoxO3a negative regulation, oxidative stress and cardiac fibroblast activation induced by TGF-β1

Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-β1

Pharmacological Effects of Caffeic Acid and Its Derivatives in Cancer: New Targeted Compounds for the Mitochondria

TGF-β1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts

Safety and Pharmacokinetics of a Combined Antioxidant Therapy against Myocardial Reperfusion Injury: A Phase 1 Randomized Clinical Trial in Healthy Humans

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