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4-Substituted Thioquinolines and Thiazoloquinolines: Potent, Selective, and Tween-80 in vitro Dependent Families of Antitubercular Agents with Moderate in vivo Activity

ChemMedChem, 2011-12, Vol.6 (12), p.2252-2263

2011

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Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of Mycobacterium tuberculosis InhA

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1276-1288

2014

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An improved one-pot method for the stereoselective synthesis of the (2S,3R)-3-amino-2-hydroxy acids: key intermediates for bestatin and amastatin

Journal of organic chemistry, 1990-03, Vol.55 (7), p.2232-2234

1990

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Mycobacterium tuberculosis Decaprenylphosphoryl-β‑d‑ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo Activity

Journal of medicinal chemistry, 2020-03, Vol.63 (5), p.2557-2576

2020

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New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold

European journal of medicinal chemistry, 2016-04, Vol.112, p.252-257

2016

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Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β‑d‑ribose Oxidase

ACS infectious diseases, 2015-12, Vol.1 (12), p.615-626

2015

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Tributyltin Cyanide, a Novel Reagent for the Stereoselective Preparation of 3-Amino-2-hydroxy Acids via Cyanohydrin Intermediates

Synthesis (Stuttgart), 1989, Vol.1989 (9), p.703-706

1989

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Cyclopropyl Carboxamides: A New Oral Antimalarial Series Derived from the Tres Cantos Anti-Malarial Set (TCAMS)

ACS medicinal chemistry letters, 2011-11, Vol.2 (11), p.840-844

2011

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Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery: e0142293

PloS one, 2015-12, Vol.10 (12)

2015

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Ketomethylenebestatin: Synthesis and Aminopeptidase Inhibition

Archiv der Pharmazie (Weinheim), 1993, Vol.326 (7), p.395-398

1993

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Synthesis of 5′-N-(α-Amino-β-mercaptoacyl)amino-5′-deoxynucleosides as potential antiviral compounds

Archiv der Pharmazie (Weinheim), 1991-08, Vol.324 (8), p.497-500

1991

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Synthesis and Antiviral Activity of 5′-O-(Substituted) Sulfamoyl Pyrimidine Nucleosides

Archiv der Pharmazie (Weinheim), 1989, Vol.322 (1), p.11-15

1989

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Synthesis of pyrimidine analogues of the nucleoside antibiotic ascamycin

Liebigs Annalen der Chemie, 1988-08, Vol.1988 (8), p.737-742

1988

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A facile synthesis of ascamycin and related analogues

Tetrahedron, 1987, Vol.43 (2), p.383-389

1987

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Aminodeoxybestatin and epi-aminodeoxybestatin: stereospecific synthesis and aminopeptidase inhibition

J. Chem. Soc., Perkin Trans. 1, 1992 (14), p.1825-1830

1992

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5′-O-[N-(Amnoacyl)Sulfamoyl]Nucleosides. Synthesis and Antiviral and Cytostatic Activities

Nucleosides & nucleotides, 1990-10, Vol.9 (7), p.985-1000

1990

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Synthesis of penicillamine- and cysteine-containing nucleoamino acids as potential antivirals and aminopeptidase B inhibitors

J. Chem. Soc., Perkin Trans. 1, 1991 (1), p.43-48

1991

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Synthesis of 6-, 7- and 8-carbon sugar analogues of potent anti-influenza 2,3-didehydro-2,3-dideoxy-N-acetylneuraminic acid derivatives

Journal of the Chemical Society, Perkin Transactions 1, 1995 (9), p.1181

1995

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Stereoselection in the synthesis of threo- and erythro-3-amino-2-hydroxy-4-phenyl- butanoic acid using chiral acetal templates

Journal of the Chemical Society. Chemical communications, 1989 (14), p.938-939

1989

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Corrigenda

Journal of the Chemical Society, Perkin Transactions 1, 1995 (15), p.1975

1995

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Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery

Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor

N-Benzyl-4-((heteroaryl)methyl)benzamides: A New Class of Direct NADH-Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity

4-Substituted Thioquinolines and Thiazoloquinolines: Potent, Selective, and Tween-80 in vitro Dependent Families of Antitubercular Agents with Moderate in vivo Activity

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of Mycobacterium tuberculosis InhA

An improved one-pot method for the stereoselective synthesis of the (2S,3R)-3-amino-2-hydroxy acids: key intermediates for bestatin and amastatin

Mycobacterium tuberculosis Decaprenylphosphoryl-β‑d‑ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo Activity

New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold

Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β‑d‑ribose Oxidase

Tributyltin Cyanide, a Novel Reagent for the Stereoselective Preparation of 3-Amino-2-hydroxy Acids via Cyanohydrin Intermediates

Cyclopropyl Carboxamides: A New Oral Antimalarial Series Derived from the Tres Cantos Anti-Malarial Set (TCAMS)

Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery: e0142293

Ketomethylenebestatin: Synthesis and Aminopeptidase Inhibition

Synthesis of 5′-N-(α-Amino-β-mercaptoacyl)amino-5′-deoxynucleosides as potential antiviral compounds

Synthesis and Antiviral Activity of 5′-O-(Substituted) Sulfamoyl Pyrimidine Nucleosides

Synthesis of pyrimidine analogues of the nucleoside antibiotic ascamycin

A facile synthesis of ascamycin and related analogues

Aminodeoxybestatin and epi-aminodeoxybestatin: stereospecific synthesis and aminopeptidase inhibition

5′-O-[N-(Amnoacyl)Sulfamoyl]Nucleosides. Synthesis and Antiviral and Cytostatic Activities

Synthesis of penicillamine- and cysteine-containing nucleoamino acids as potential antivirals and aminopeptidase B inhibitors

Synthesis of 6-, 7- and 8-carbon sugar analogues of potent anti-influenza 2,3-didehydro-2,3-dideoxy-N-acetylneuraminic acid derivatives

Stereoselection in the synthesis of threo- and erythro-3-amino-2-hydroxy-4-phenyl- butanoic acid using chiral acetal templates

Corrigenda

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