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Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably Expressed in HEK-293 Cells

PloS one, 2016-08, Vol.11 (8), p.e0161450-e0161450

2016

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Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (29), p.E2724-E2732

2013

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Therapeutic potential of KCa3.1 blockers: recent advances and promising trends

Expert review of clinical pharmacology, 2010-05, Vol.3 (3), p.385-396

2010

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Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough

The Journal of clinical investigation, 2022-09, Vol.132 (18)

2022

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Pharmacological Removal of Human Ether-Ã -go-go-Related Gene Potassium Channel Inactivation by 3-Nitro-N-(4-phenoxyphenyl) Benzamide (ICA-105574)

Molecular pharmacology, 2010-01, Vol.77 (1), p.58-68

2010

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Voltage-gated potassium channels as therapeutic targets

Nature reviews. Drug discovery, 2009-12, Vol.8 (12), p.982-1001

2009

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Pharmacological modulation of voltage-gated potassium channels as a therapeutic strategy

Expert opinion on therapeutic patents, 2010-11, Vol.20 (11), p.1471-1503

Castle, Neil A

2010

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GI‐530159, a novel, selective, mechanosensitive two‐pore‐domain potassium (K2P) channel opener, reduces rat dorsal root ganglion neuron excitability

British journal of pharmacology, 2018-06, Vol.175 (12), p.2272-2283

2018

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PF‐06526290 can both enhance and inhibit conduction through voltage‐gated sodium channels

British journal of pharmacology, 2018-07, Vol.175 (14), p.2926-2939

2018

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Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation

British journal of pharmacology, 2015-10, Vol.172 (20), p.4905-4918

2015

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Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes

Bioorganic & medicinal chemistry letters, 2017-11, Vol.27 (21), p.4805-4811

2017

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Aquaporins as targets for drug discovery

Drug Discovery Today, 2005-04, Vol.10 (7), p.485-493

Castle, Neil A.

2005

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Retracted: Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation

British journal of pharmacology, 2015-10, Vol.172 (20), p.4905-4918

2015

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Discovery and in Vitro Optimization of 3‑Sulfamoylbenzamides as ROMK Inhibitors

ACS medicinal chemistry letters, 2018-02, Vol.9 (2), p.125-130

2018

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Aryl sulfonamido indane inhibitors of the Kv1.5 ion channel

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (10), p.2849-2853

2007

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The Effect of κ-Opioid Receptor Agonists on Tetrodotoxin-Resistant Sodium Channels in Primary Sensory Neurons

Anesthesia and analgesia, 2009-08, Vol.109 (2), p.632-640

2009

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Aryl sulfonamido tetralin inhibitors of the Kv1.5 ion channel

Bioorganic & medicinal chemistry letters, 2009-06, Vol.19 (11), p.3063-3066

2009

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Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough

The Journal of clinical investigation, 2022-09, Vol.132 (18), p.1-15

2022

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In vitro and in vivo characterization of a novel naphthylamide ATP‐sensitive K+ channel opener, A‐151892

British journal of pharmacology, 2004-09, Vol.143 (1), p.81-90

2004

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Structure–activity relationship of a novel class of naphthyl amide KATP channel openers

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1741-1744

2003

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Electrophysiological Analysis of Heterologously Expressed Kv and SK/IK Potassium Channels

Current Protocols in Pharmacology, 2003-05, Vol.20 (1), p.11.5.1-11.5.27

2003

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Voltage-gated Potassium Channels as Therapeutic Drug Targets

Nature reviews. Drug discovery, 2009-12, Vol.8 (12), p.982-1001

2009

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Therapeutic potential of KCa3.1 blockers: an overview of recent advances, and promising trends

Expert review of clinical pharmacology, 2010-05, Vol.3 (3), p.385-396

2010

Volltextzugriff (PDF)

Therapeutic potential of K Ca 3.1 blockers: recent advances and promising trends

Expert review of clinical pharmacology, 2010-05, Vol.3 (3), p.385-396

2010

Volltextzugriff (PDF)

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Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably Expressed in HEK-293 Cells

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels

Therapeutic potential of KCa3.1 blockers: recent advances and promising trends

Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough

Pharmacological Removal of Human Ether-Ã -go-go-Related Gene Potassium Channel Inactivation by 3-Nitro-N-(4-phenoxyphenyl) Benzamide (ICA-105574)

Voltage-gated potassium channels as therapeutic targets

Pharmacological modulation of voltage-gated potassium channels as a therapeutic strategy

GI‐530159, a novel, selective, mechanosensitive two‐pore‐domain potassium (K2P) channel opener, reduces rat dorsal root ganglion neuron excitability

PF‐06526290 can both enhance and inhibit conduction through voltage‐gated sodium channels

Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation

Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes

Aquaporins as targets for drug discovery

Retracted: Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation

Discovery and in Vitro Optimization of 3‑Sulfamoylbenzamides as ROMK Inhibitors

Aryl sulfonamido indane inhibitors of the Kv1.5 ion channel

The Effect of κ-Opioid Receptor Agonists on Tetrodotoxin-Resistant Sodium Channels in Primary Sensory Neurons

Aryl sulfonamido tetralin inhibitors of the Kv1.5 ion channel

Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough

In vitro and in vivo characterization of a novel naphthylamide ATP‐sensitive K+ channel opener, A‐151892

Structure–activity relationship of a novel class of naphthyl amide KATP channel openers

Electrophysiological Analysis of Heterologously Expressed Kv and SK/IK Potassium Channels

Voltage-gated Potassium Channels as Therapeutic Drug Targets

Therapeutic potential of KCa3.1 blockers: an overview of recent advances, and promising trends

Therapeutic potential of K Ca 3.1 blockers: recent advances and promising trends

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