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Immunosuppressive enzymes in the tumor microenvironment

FEBS letters, 2017-10, Vol.591 (19), p.3135-3157

2017

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An Overview of l-Amino Acid Oxidase Functions from Bacteria to Mammals: Focus on the Immunoregulatory Phenylalanine Oxidase IL4I1

Molecules (Basel, Switzerland), 2017-12, Vol.22 (12), p.2151

2017

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IL-4-Induced Gene 1: A Negative Immune Checkpoint Controlling B Cell Differentiation and Activation

The Journal of immunology (1950), 2018-02, Vol.200 (3), p.1027-1038

2018

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The IL4I1 Enzyme: A New Player in the Immunosuppressive Tumor Microenvironment

Cells (Basel, Switzerland), 2019-07, Vol.8 (7), p.757

2019

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Editorial: Immunosuppressive Amino Acid Catabolizing Enzymes in Heallth and Disease

Frontiers in immunology, 2021-05, Vol.12, p.689864-689864

2021

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Control of T-Cell Activation and Signaling by Amino-Acid Catabolizing Enzymes

Frontiers in cell and developmental biology, 2020-12, Vol.8, p.613416-613416

2020

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IL4‐induced gene 1 is secreted at the immune synapse and modulates TCR activation independently of its enzymatic activity

European journal of immunology, 2018-01, Vol.48 (1), p.106-119

2018

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Antibacterial properties of the mammalian L-amino acid oxidase IL4I1

PloS one, 2013-01, Vol.8 (1), p.e54589

2013

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What role for AHR activation in IL4I1-mediated immunosuppression ?

Oncoimmunology, 2021-01, Vol.10 (1), p.1924500-1924500

2021

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IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike

Frontiers in immunology, 2022-09, Vol.13, p.982839-982839

2022

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Quantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to Pulmonary Aspergillus fumigatus Infection

Molecular & cellular proteomics, 2017-12, Vol.16 (12), p.2184-2198

2017

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IL4I1 Accelerates the Expansion of Effector CD8 + T Cells at the Expense of Memory Precursors by Increasing the Threshold of T-Cell Activation

Frontiers in immunology, 2020-12, Vol.11, p.600012-600012

2020

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Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma

Blood, 2009-08, Vol.114 (6), p.1236-1242

2009

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Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma

Blood, 2004-07, Vol.104 (2), p.543-549

2004

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IL4-induced gene 1 promotes tumor growth by shaping the immune microenvironment in melanoma

Oncoimmunology, 2017-03, Vol.6 (3), p.e1278331-e1278331

2017

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Dichotomy between factors inducing the immunosuppressive enzyme IL-4-induced gene 1 (IL4I1) in B lymphocytes and mononuclear phagocytes

European journal of immunology, 2010-09, Vol.40 (9), p.2557-2568

2010

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Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of Th Cytokines Production by Activated CD4+ T Lymphocytes In Vitro, and Defective Red Blood Cell Alloimmune Response In Vivo

PloS one, 2015-08, Vol.10 (8), p.e0136885-e0136885

2015

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Membrane recruitment of Rac1 triggers phagocytosis

Journal of cell science, 2000-09, Vol.113 ( Pt 17) (17), p.2955-2961

2000

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Antiproliferative Activity of trans-Avicennol from Zanthoxylum chiloperone var. angustifolium against Human Cancer Stem Cells

Journal of natural products (Washington, D.C.), 2012-02, Vol.75 (2), p.257-261

2012

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Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation

Current biology, 1999-04, Vol.9 (7), p.351-361

1999

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Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties

European journal of immunology, 2024-04, Vol.54 (4), p.e2350615-n/a

2024

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The immunosuppressive enzyme IL4I1 promotes FoxP3+ regulatory T lymphocyte differentiation

European journal of immunology, 2015-06, Vol.45 (6), p.1772-1782

2015

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ARL5b inhibits human rhinovirus 16 propagation and impairs macrophage-mediated bacterial clearance

EMBO reports, 2024-03, Vol.25 (3), p.1156-1175

2024

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Emerging Role of IL-4–Induced Gene 1 as a Prognostic Biomarker Affecting the Local T-Cell Response in Human Cutaneous Melanoma

Journal of investigative dermatology, 2018-12, Vol.138 (12), p.2625-2634

2018

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Identification of inhibitors of the immunosuppressive enzyme IL4I1

Bioorganic chemistry, 2020-01, Vol.94, p.103463, Article 103463

2020

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Immunosuppressive enzymes in the tumor microenvironment

An Overview of l-Amino Acid Oxidase Functions from Bacteria to Mammals: Focus on the Immunoregulatory Phenylalanine Oxidase IL4I1

IL-4-Induced Gene 1: A Negative Immune Checkpoint Controlling B Cell Differentiation and Activation

The IL4I1 Enzyme: A New Player in the Immunosuppressive Tumor Microenvironment

Editorial: Immunosuppressive Amino Acid Catabolizing Enzymes in Heallth and Disease

Control of T-Cell Activation and Signaling by Amino-Acid Catabolizing Enzymes

IL4‐induced gene 1 is secreted at the immune synapse and modulates TCR activation independently of its enzymatic activity

Antibacterial properties of the mammalian L-amino acid oxidase IL4I1

What role for AHR activation in IL4I1-mediated immunosuppression ?

IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike

Quantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to Pulmonary Aspergillus fumigatus Infection

IL4I1 Accelerates the Expansion of Effector CD8 + T Cells at the Expense of Memory Precursors by Increasing the Threshold of T-Cell Activation

Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma

Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma

IL4-induced gene 1 promotes tumor growth by shaping the immune microenvironment in melanoma

Dichotomy between factors inducing the immunosuppressive enzyme IL-4-induced gene 1 (IL4I1) in B lymphocytes and mononuclear phagocytes

Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of Th Cytokines Production by Activated CD4+ T Lymphocytes In Vitro, and Defective Red Blood Cell Alloimmune Response In Vivo

Membrane recruitment of Rac1 triggers phagocytosis

Antiproliferative Activity of trans-Avicennol from Zanthoxylum chiloperone var. angustifolium against Human Cancer Stem Cells

Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation

Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties

The immunosuppressive enzyme IL4I1 promotes FoxP3+ regulatory T lymphocyte differentiation

ARL5b inhibits human rhinovirus 16 propagation and impairs macrophage-mediated bacterial clearance

Emerging Role of IL-4–Induced Gene 1 as a Prognostic Biomarker Affecting the Local T-Cell Response in Human Cutaneous Melanoma

Identification of inhibitors of the immunosuppressive enzyme IL4I1

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