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A cell-based assay for CD63-containing extracellular vesicles

PloS one, 2019-07, Vol.14 (7), p.e0220007-e0220007

2019

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A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol

The Journal of neuroscience, 2021-12, Vol.41 (49), p.10054-10064

2021

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Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol

Journal of lipid research, 2023-04, Vol.64 (4), p.100350-100350

2023

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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

Journal of neuroinflammation, 2020-06, Vol.17 (1), p.192-192, Article 192

2020

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Neurosteroids mediate and modulate the effects of pro-inflammatory stimulation and toll-like receptors on hippocampal plasticity and learning

PloS one, 2024-06, Vol.19 (6), p.e0304481

2024

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Sequestration of Toxic Oligomers by HspB1 as a Cytoprotective Mechanism

Molecular and Cellular Biology, 2011-08, Vol.31 (15), p.3146-3157

2011

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Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity

Nature genetics, 2009-03, Vol.41 (3), p.316-323

2009

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Structure of cellular ESCRT-III spirals and their relationship to HIV budding

eLife, 2014-05, Vol.3

2014

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Role of Ser129 phosphorylation of α-synuclein in melanoma cells

Journal of cell science, 2013-01, Vol.126 (Pt 2), p.696-704

2013

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Nucleated Conformational Conversion and the Replication of Conformational Information by a Prion Determinant

Science (American Association for the Advancement of Science), 2000-08, Vol.289 (5483), p.1317-1321

2000

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Atypical AAA+ Subunit Packing Creates an Expanded Cavity for Disaggregation by the Protein-Remodeling Factor Hsp104

Cell, 2007-12, Vol.131 (7), p.1366-1377

2007

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Behavioral defects in chaperone-deficient Alzheimer's disease model mice

PloS one, 2011-02, Vol.6 (2), p.e16550

2011

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Ssd1 Is Required for Thermotolerance and Hsp104-Mediated Protein Disaggregation in Saccharomyces cerevisiae

Molecular and Cellular Biology, 2009-01, Vol.29 (1), p.187-200

2009

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Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

Neuron (Cambridge, Mass.), 2024-02, Vol.112 (3), p.384-403.e8

2024

Volltextzugriff (PDF)

Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins

Neuron (Cambridge, Mass.), 2024-04, Vol.112 (7), p.1100-1109.e5

2024

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Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma

PloS one, 2011-03, Vol.6 (3), p.e17177-e17177

2011

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Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy

The Journal of experimental medicine, 2024-04, Vol.221 (4)

2024

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Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation

Acta neuropathologica, 2023-06, Vol.145 (6), p.749-772

2023

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A chaperone pathway in protein disaggregation. Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104

The Journal of biological chemistry, 2005-06, Vol.280 (25), p.23869-23875

2005

Volltextzugriff (PDF)

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

Neuron (Cambridge, Mass.), 2024-06, Vol.112 (12), p.2079-2079

2024

Volltextzugriff (PDF)

Defining a Pathway of Communication from the C-Terminal Peptide Binding Domain to the N-Terminal ATPase Domain in a AAA Protein

Molecular cell, 2002-04, Vol.9 (4), p.751-760

2002

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25‐Hydroxycholesterol modulates tau‐mediated neurodegeneration and microglial chemotaxis and phagocytosis

Alzheimer's & dementia, 2021-12, Vol.17, p.e056404-n/a

2021

Volltextzugriff (PDF)

Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol

Journal of lipid research, 2023-04, Vol.64 (4), p.100350, Article 100350

2023

Volltextzugriff (PDF)

A Chaperone Pathway in Protein Disaggregation

The Journal of biological chemistry, 2005-06, Vol.280 (25), p.23869-23875

2005

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Tracking the intracellular itinerary of APP and de novo Aβ generation using click chemistry

Alzheimer's & dementia, 2023-12, Vol.19 (S13)

2023

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A cell-based assay for CD63-containing extracellular vesicles

A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol

Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

Neurosteroids mediate and modulate the effects of pro-inflammatory stimulation and toll-like receptors on hippocampal plasticity and learning

Sequestration of Toxic Oligomers by HspB1 as a Cytoprotective Mechanism

Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity

Structure of cellular ESCRT-III spirals and their relationship to HIV budding

Role of Ser129 phosphorylation of α-synuclein in melanoma cells

Nucleated Conformational Conversion and the Replication of Conformational Information by a Prion Determinant

Atypical AAA+ Subunit Packing Creates an Expanded Cavity for Disaggregation by the Protein-Remodeling Factor Hsp104

Behavioral defects in chaperone-deficient Alzheimer's disease model mice

Ssd1 Is Required for Thermotolerance and Hsp104-Mediated Protein Disaggregation in Saccharomyces cerevisiae

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins

Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma

Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy

Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation

A chaperone pathway in protein disaggregation. Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

Defining a Pathway of Communication from the C-Terminal Peptide Binding Domain to the N-Terminal ATPase Domain in a AAA Protein

25‐Hydroxycholesterol modulates tau‐mediated neurodegeneration and microglial chemotaxis and phagocytosis

Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol

A Chaperone Pathway in Protein Disaggregation

Tracking the intracellular itinerary of APP and de novo Aβ generation using click chemistry

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