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CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid

Nature communications, 2020-08, Vol.11 (1), p.4090-4090, Article 4090

2020

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Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks

Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6376), p.698-701

2018

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Accurate design of megadalton-scale two-component icosahedral protein complexes

Science (American Association for the Advancement of Science), 2016-07, Vol.353 (6297), p.389-394

2016

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Structure of a 16-nm Cage Designed by Using Protein Oligomers

Science (American Association for the Advancement of Science), 2012-06, Vol.336 (6085), p.1129-1129

2012

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Synthesis, Structure, and Metalation of Two New Highly Porous Zirconium Metal–Organic Frameworks

Inorganic chemistry, 2012-06, Vol.51 (12), p.6443-6445

2012

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Structure-based inhibitors of amyloid beta core suggest a common interface with tau

eLife, 2019-10, Vol.8

2019

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Engineering an allosteric transcription factor to respond to new ligands

Nature methods, 2016-02, Vol.13 (2), p.177

2016

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The shape of the DNA minor groove directs binding by the DNA-bending protein Fis

Genes & development, 2010-04, Vol.24 (8), p.814-826

2010

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Atomic View of a Toxic Amyloid Small Oligomer

Science (American Association for the Advancement of Science), 2012-03, Vol.335 (6073), p.1228-1231

2012

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Molecular basis for amyloid-β polymorphism

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (41), p.16938-16943

2011

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Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2

Nature structural & molecular biology, 2018-04, Vol.25 (4), p.311

2018

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Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity

eLife, 2017-01, Vol.6 (1, 2017)

2017

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The Crystal Structure of Mouse VDAC1 at 2.3 Å Resolution Reveals Mechanistic Insights into Metabolite Gating

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (46), p.17742-17747

2008

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Uncovering the Mechanism of Aggregation of Human Transthyretin

The Journal of biological chemistry, 2015-11, Vol.290 (48), p.28932-28943

2015

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Computational design of self-assembling cyclic protein homo-oligomers

Nature chemistry, 2017-04, Vol.9 (4), p.353

2017

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Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (40), p.11232-11236

2016

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Toward the Structural Genomics of Complexes: Crystal Structure of a PE/PPE Protein Complex from Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (21), p.8060-8065

2006

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Origins of stereoselectivity in evolved ketoreductases

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (51), p.E7065-E7072

2015

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Cooperative DNA binding by proteins through DNA shape complementarity

Nucleic acids research, 2019-09, Vol.47 (16), p.8874

2019

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The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (16), p.5771-5771

2014

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Structure-based inhibitors halt prion-like seeding by Alzheimer’s disease–and tauopathy–derived brain tissue samples

The Journal of biological chemistry, 2019-11, Vol.294 (44), p.16451-16464

2019

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Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

Protein science, 2010-05, Vol.19 (5), p.1031-1043

2010

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Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies

Biochemical and biophysical research communications, 2017-06, Vol.488 (1), p.129-135

2017

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Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface

Nature communications, 2019-07, Vol.10 (1), p.3357-12, Article 3357

2019

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Structure and dynamics of a conformationally constrained nitroxide side chain and applications in EPR spectroscopy

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (39), p.16241-16246

2011

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CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid

Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks

Accurate design of megadalton-scale two-component icosahedral protein complexes

Structure of a 16-nm Cage Designed by Using Protein Oligomers

Synthesis, Structure, and Metalation of Two New Highly Porous Zirconium Metal–Organic Frameworks

Structure-based inhibitors of amyloid beta core suggest a common interface with tau

Engineering an allosteric transcription factor to respond to new ligands

The shape of the DNA minor groove directs binding by the DNA-bending protein Fis

Atomic View of a Toxic Amyloid Small Oligomer

Molecular basis for amyloid-β polymorphism

Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2

Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity

The Crystal Structure of Mouse VDAC1 at 2.3 Å Resolution Reveals Mechanistic Insights into Metabolite Gating

Uncovering the Mechanism of Aggregation of Human Transthyretin

Computational design of self-assembling cyclic protein homo-oligomers

Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED

Toward the Structural Genomics of Complexes: Crystal Structure of a PE/PPE Protein Complex from Mycobacterium tuberculosis

Origins of stereoselectivity in evolved ketoreductases

Cooperative DNA binding by proteins through DNA shape complementarity

The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity

Structure-based inhibitors halt prion-like seeding by Alzheimer’s disease–and tauopathy–derived brain tissue samples

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies

Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface

Structure and dynamics of a conformationally constrained nitroxide side chain and applications in EPR spectroscopy

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