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FKBP12 binds to the cardiac ryanodine receptor with negative cooperativity: implications for heart muscle physiology in health and disease

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2023-06, Vol.378 (1879), p.20220169

2023

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Efavirenz as a potential drug for the treatment of triple-negative breast cancers

Clinical & translational oncology, 2021-02, Vol.23 (2), p.353-363

2021

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Interactions between dihydropyridine receptors and ryanodine receptors in striated muscle

Progress in Biophysics and Molecular Biology, 2002-05, Vol.79 (1), p.45-75

2002

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Multiple actions of imperatoxin A on ryanodine receptors: interactions with the II-III loop "A" fragment

The Journal of biological chemistry, 2004-03, Vol.279 (12), p.11853-11862

2004

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The random-coil 'C' fragment of the dihydropyridine receptor II-III loop can activate or inhibit native skeletal ryanodine receptors

Biochemical journal, 2003-06, Vol.372 (Pt 2), p.305-316

2003

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The recombinant dihydropyridine receptor II-III loop and partly structured 'C' region peptides modify cardiac ryanodine receptor activity

Biochemical journal, 2005-02, Vol.385 (Pt 3), p.803-813

2005

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The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha-helical dihydropyridine receptor segment

Biochemical journal, 2003-03, Vol.370 (Pt 2), p.517-527

2003

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A Structural Requirement for Activation of Skeletal Ryanodine Receptors by Peptides of the Dihydropyridine Receptor II-III Loop

The Journal of biological chemistry, 2000-04, Vol.275 (16), p.11631-11637

2000

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Ring Flexibility within Tricyclic Antidepressant Drugs

Journal of pharmaceutical sciences, 2001-06, Vol.90 (6), p.713-721

2001

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Structural Determinants for Activation or Inhibition of Ryanodine Receptors by Basic Residues in the Dihydropyridine Receptor II-III Loop

Biophysical journal, 2001-06, Vol.80 (6), p.2715-2726

2001

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Role of the active-site carboxylate in dihydrofolate reductase: kinetic and spectroscopic studies of the aspartate 26-->asparagine mutant of the Lactobacillus casei enzyme

Biochemistry (Easton), 1995-03, Vol.34 (9), p.2872

1995

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Activating the ryanodine receptor with dihydropyridine receptor II-III loop segments: size and charge do matter

Frontiers in bioscience, 2004-09, Vol.9 (1-3), p.2860

2004

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Alternative splicing of RyR1 alters the efficacy of skeletal EC coupling

Cell calcium (Edinburgh), 2009-03, Vol.45 (3), p.264-274

2009

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Exploiting Peptidomimetics to Synthesize Compounds That Activate Ryanodine Receptor Calcium Release Channels

ChemMedChem, 2018-09, Vol.13 (18), p.1957-1971

2018

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Effects of single-residue substitutions on negative cooperativity in ligand binding to dihydrofolate reductase

Protein engineering, 1997-07, Vol.10 (7), p.815-826

1997

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Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling [version 1; peer review: 4 approved]

F1000 research, 2018, Vol.7, p.1851

2018

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Physiology and Pharmacology of Ryanodine Receptor Calcium Release Channels

Advances in pharmacology (1990), 2017, Vol.79, p.287-324

2017

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Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca2+ and phosphorylation

Biophysical journal, 2005-05, Vol.88 (5), p.3444-3454

2005

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NMR studies of the conformational interconversion of butaclamol in solution

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.2043-2049

1991

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Structural model of human IL‐13 defines the spatial interactions with the IL‐13Rα/IL‐4Rα receptor

Immunology and cell biology, 2001-08, Vol.79 (4), p.332-339

2001

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An NMR and theoretical study of the conformation and internal flexibility of butaclamol hydrochloride

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.2036-2043

1991

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The influence of aspartate 26 on the tautomeric forms of folate bound to Lactobacillus casei dihydrofolate reductase

FEBS letters, 1997-02, Vol.402 (2), p.157-161

1997

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Malignant hyperthermia mutation sites in the Leu super(2442)-Pro super(2477) (DP4) region of RyR1 (ryanodine receptor 1) are clustered in a structurally and functionally definable area

Biochemical journal, 2007-01, Vol.401 (1), p.333-339

2007

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Role of the Active-Site Carboxylate in Dihydrofolate Reductase: Kinetic and Spectroscopic Studies of the Aspartate 26 .fwdarw. Asparagine Mutant of the Lactobacillus casei Enzyme

Biochemistry (Easton), 1995-03, Vol.34 (9), p.2872-2882

1995

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High-Level Expression and Isotopic Labeling of Lactobacillus casei Dihydrofolate Reductase for Nuclear Magnetic Resonance Spectroscopy

Protein expression and purification, 1995-06, Vol.6 (3), p.237-243

1995

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FKBP12 binds to the cardiac ryanodine receptor with negative cooperativity: implications for heart muscle physiology in health and disease

Efavirenz as a potential drug for the treatment of triple-negative breast cancers

Interactions between dihydropyridine receptors and ryanodine receptors in striated muscle

Multiple actions of imperatoxin A on ryanodine receptors: interactions with the II-III loop "A" fragment

The random-coil 'C' fragment of the dihydropyridine receptor II-III loop can activate or inhibit native skeletal ryanodine receptors

The recombinant dihydropyridine receptor II-III loop and partly structured 'C' region peptides modify cardiac ryanodine receptor activity

The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha-helical dihydropyridine receptor segment

A Structural Requirement for Activation of Skeletal Ryanodine Receptors by Peptides of the Dihydropyridine Receptor II-III Loop

Ring Flexibility within Tricyclic Antidepressant Drugs

Structural Determinants for Activation or Inhibition of Ryanodine Receptors by Basic Residues in the Dihydropyridine Receptor II-III Loop

Role of the active-site carboxylate in dihydrofolate reductase: kinetic and spectroscopic studies of the aspartate 26-->asparagine mutant of the Lactobacillus casei enzyme

Activating the ryanodine receptor with dihydropyridine receptor II-III loop segments: size and charge do matter

Alternative splicing of RyR1 alters the efficacy of skeletal EC coupling

Exploiting Peptidomimetics to Synthesize Compounds That Activate Ryanodine Receptor Calcium Release Channels

Effects of single-residue substitutions on negative cooperativity in ligand binding to dihydrofolate reductase

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling [version 1; peer review: 4 approved]

Physiology and Pharmacology of Ryanodine Receptor Calcium Release Channels

Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca2+ and phosphorylation

NMR studies of the conformational interconversion of butaclamol in solution

Structural model of human IL‐13 defines the spatial interactions with the IL‐13Rα/IL‐4Rα receptor

An NMR and theoretical study of the conformation and internal flexibility of butaclamol hydrochloride

The influence of aspartate 26 on the tautomeric forms of folate bound to Lactobacillus casei dihydrofolate reductase

Malignant hyperthermia mutation sites in the Leu super(2442)-Pro super(2477) (DP4) region of RyR1 (ryanodine receptor 1) are clustered in a structurally and functionally definable area

Role of the Active-Site Carboxylate in Dihydrofolate Reductase: Kinetic and Spectroscopic Studies of the Aspartate 26 .fwdarw. Asparagine Mutant of the Lactobacillus casei Enzyme

High-Level Expression and Isotopic Labeling of Lactobacillus casei Dihydrofolate Reductase for Nuclear Magnetic Resonance Spectroscopy

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