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Exosomes regulate neurogenesis and circuit assembly

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (32), p.16086-16094

2019

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KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome

Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (3), p.751-756

2016

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Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC-Derived Neural 3D Cultures

Toxicological sciences, 2019-01, Vol.167 (1), p.58-76

2019

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Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids

EMBO molecular medicine, 2021-01, Vol.13 (1), p.e12523-n/a

2021

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Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroids

PloS one, 2020-10, Vol.15 (10), p.e0240991-e0240991

2020

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Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function

PloS one, 2019-02, Vol.14 (2), p.e0212553-e0212553

2019

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Human iPSC-Derived 2D and 3D Platforms for Rapidly Assessing Developmental, Functional, and Terminal Toxicities in Neural Cells

International journal of molecular sciences, 2021-02, Vol.22 (4), p.1908

2021

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Maintenance and differentiation of neural stem cells

Wiley interdisciplinary reviews. Mechanisms of disease, 2011-01, Vol.3 (1), p.107-114

2011

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The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome-derived neural precursor cells

Biochemical and biophysical research communications, 2017-12, Vol.494 (3-4), p.504-510

2017

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A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

Cell, 2010-11, Vol.143 (4), p.527-539

2010

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Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA

Nature neuroscience, 2014-09, Vol.17 (9), p.1180-1189

2014

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Altered neuronal network and rescue in a human MECP2 duplication model

Molecular psychiatry, 2016-02, Vol.21 (2), p.178-188

2016

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Connexin43 as a Gene Therapy To Circumvent Arrhythmogenic Cardiomyopathy

The FASEB journal, 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.04812

2021

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Profiling of seizurogenic liability compounds using high-throughput human iPSC–derived neuronal 3D cultures

Journal of pharmacological and toxicological methods, 2020-09, Vol.105, p.106861, Article 106861

2020

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Abstract P449: Connexin43 As A Therapeutic For Arrhythmogenic Right Ventricular Cardiomyopathy

Circulation research, 2021-09, Vol.129 (Suppl_1)

2021

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Connexin43 as a Therapeutic To Restore Cardiac Structure in Arrhythmogenic Heart Disease

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Hight-throughput profiling of seizuregenic liability using human iPSC–derived neuronal 3D cultures

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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Using hiPSC-derived neuronal cultures to assess the safety of pre-screened potential therapeutic compounds against Zika Virus

Journal of pharmacological and toxicological methods, 2018-09, Vol.93, p.137-137

2018

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Functional evaluation of neurotoxic compounds using human iPSC–derived neuronal 3D cultures

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3

Human molecular genetics, 2017-01, Vol.26 (2), p.270-281

2017

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Altered Gene Expression of Thyroid Hormone Transporters and Deiodinases in iPS MeCP2-Knockout Cells-Derived Neurons

Molecular neurobiology, 2019-12, Vol.56 (12), p.8277-8295

2019

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Pig models of neurodegenerative disorders: Utilization in cell replacement-based preclinical safety and efficacy studies

Journal of comparative neurology (1911), 2014-08, Vol.522 (12), p.2784-2801

2014

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High-throughput and high-content safety pharmacology assessments with 3-dimensional human induced pluripotent stem cell-derived cortical spheroid platforms

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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Stem cells and modeling of autism spectrum disorders

Experimental neurology, 2014-10, Vol.260, p.33-43

2014

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Kinin-B2 Receptor Activity Determines the Differentiation Fate of Neural Stem Cells

The Journal of biological chemistry, 2012-12, Vol.287 (53), p.44046-44061

2012

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Exosomes regulate neurogenesis and circuit assembly

KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome

Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC-Derived Neural 3D Cultures

Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids

Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroids

Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function

Human iPSC-Derived 2D and 3D Platforms for Rapidly Assessing Developmental, Functional, and Terminal Toxicities in Neural Cells

Maintenance and differentiation of neural stem cells

The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome-derived neural precursor cells

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA

Altered neuronal network and rescue in a human MECP2 duplication model

Connexin43 as a Gene Therapy To Circumvent Arrhythmogenic Cardiomyopathy

Profiling of seizurogenic liability compounds using high-throughput human iPSC–derived neuronal 3D cultures

Abstract P449: Connexin43 As A Therapeutic For Arrhythmogenic Right Ventricular Cardiomyopathy

Connexin43 as a Therapeutic To Restore Cardiac Structure in Arrhythmogenic Heart Disease

Hight-throughput profiling of seizuregenic liability using human iPSC–derived neuronal 3D cultures

Using hiPSC-derived neuronal cultures to assess the safety of pre-screened potential therapeutic compounds against Zika Virus

Functional evaluation of neurotoxic compounds using human iPSC–derived neuronal 3D cultures

IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3

Altered Gene Expression of Thyroid Hormone Transporters and Deiodinases in iPS MeCP2-Knockout Cells-Derived Neurons

Pig models of neurodegenerative disorders: Utilization in cell replacement-based preclinical safety and efficacy studies

High-throughput and high-content safety pharmacology assessments with 3-dimensional human induced pluripotent stem cell-derived cortical spheroid platforms

Stem cells and modeling of autism spectrum disorders

Kinin-B2 Receptor Activity Determines the Differentiation Fate of Neural Stem Cells

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