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Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse

PloS one, 2017-12, Vol.12 (12), p.e0184876

2017

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In vivo pharmacological interactions between a type II positive allosteric modulator of α7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model

British journal of pharmacology, 2013-06, Vol.169 (3), p.567-579

2013

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Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice

Psychopharmacology, 2013-04, Vol.226 (4), p.763-768

2013

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Formulation and Characterization of Conjugate Vaccines to Reduce Opioid Use Disorders Suitable for Pharmaceutical Manufacturing and Clinical Evaluation

Molecular pharmaceutics, 2019-06, Vol.16 (6), p.2364-2375

2019

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Examination of the metabolite hydroxybupropion in the reinforcing and aversive stimulus effects of nicotine in rats

Psychopharmacology, 2015-08, Vol.232 (15), p.2763-2771

2015

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The frequency of early-activated hapten-specific B cell subsets predicts the efficacy of vaccines for nicotine dependence

Vaccine, 2015-11, Vol.33 (46), p.6332-6339

2015

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Functional reorganization of the presynaptic dopaminergic terminal in parkinsonism

Neuroscience, 2011-10, Vol.193, p.310-322

2011

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Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

ACS chemical neuroscience, 2017-01, Vol.8 (1), p.115-127

2017

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A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic

Neuropsychopharmacology (New York, N.Y.), 2015-08, Vol.40 (9), p.2059-2065

2015

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Effects of murine-derived anti-methamphetamine monoclonal antibodies on (+)-methamphetamine self-administration in the rat

The Journal of pharmacology and experimental therapeutics, 2004-06, Vol.309 (3), p.1248

2004

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Pharmacotherapies for Treatment of Cocaine Abuse: Preclinical Aspects

Journal of medicinal chemistry, 1999-07, Vol.42 (15), p.2721-2736

1999

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Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice

Psychopharmacologia, 2012-09, Vol.223 (2), p.159-168

2012

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An investigation of bupropion substitution for the interoceptive stimulus effects of nicotine

Journal of psychopharmacology (Oxford), 2010-06, Vol.24 (6), p.817-828

2010

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Effects of the monoamine uptake inhibitors RTI-112 and RTI-113 on cocaine- and food-maintained responding in rhesus monkeys

Pharmacology, biochemistry and behavior, 2009-01, Vol.91 (3), p.333-338

2009

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Effect of nicotine and alpha‐7 nicotinic modulators on visceral pain‐induced conditioned place aversion in mice

European journal of pain, 2018-09, Vol.22 (8), p.1419-1427

2018

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Identification of the First trans-(3R,4R)- Dimethyl-4-(3-hydroxyphenyl)piperidine Derivative To Possess Highly Potent and Selective Opioid κ Receptor Antagonist Activity

Journal of medicinal chemistry, 2001-08, Vol.44 (17), p.2687-2690

2001

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Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2-exo-2-(2‘-Substituted 5‘-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine Analogues

Journal of medicinal chemistry, 2001-06, Vol.44 (13), p.2229-2237

2001

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In vivo pharmacological interactions between a type II positive allosteric modulator of [alpha]7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model

British journal of pharmacology, 2013-06, Vol.169 (3), p.567

2013

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Anti‐nociception mediated by a κ opioid receptor agonist is blocked by a δ receptor agonist

British journal of pharmacology, 2015-01, Vol.172 (2), p.691-703

2015

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Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse

Psychopharmacology, 2010-06, Vol.210 (2), p.285-294

2010

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Structure–activity relationship of trihexyphenidyl analogs with respect to the dopamine transporter in the on going search for a cocaine inhibitor

European journal of medicinal chemistry, 2005-10, Vol.40 (10), p.1013-1021

2005

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Effects of the specific alpha 4 beta 2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice

Psychopharmacology, 2012-09, Vol.223 (2), p.159-168

2012

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Cocaine and 3β-(4'-substituted phenyl)tropane-2β-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter

Journal of medicinal chemistry, 1995-01, Vol.38 (2), p.379-388

1995

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Synthesis and Nicotinic Acetylcholine Receptor Binding Properties of exo-2-(2‘-Fluoro-5‘-pyridinyl)-7-azabicyclo- [2.2.1]heptane: A New Positron Emission Tomography Ligand for Nicotinic Receptors

Journal of medicinal chemistry, 1997-07, Vol.40 (15), p.2293-2295

1997

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Self-administration of cocaine and the cocaine analog RTI-113: Relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys

Synapse (New York, N.Y.), 2002-01, Vol.43 (1), p.78-85

2002

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Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse

In vivo pharmacological interactions between a type II positive allosteric modulator of α7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model

Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice

Formulation and Characterization of Conjugate Vaccines to Reduce Opioid Use Disorders Suitable for Pharmaceutical Manufacturing and Clinical Evaluation

Examination of the metabolite hydroxybupropion in the reinforcing and aversive stimulus effects of nicotine in rats

The frequency of early-activated hapten-specific B cell subsets predicts the efficacy of vaccines for nicotine dependence

Functional reorganization of the presynaptic dopaminergic terminal in parkinsonism

Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic

Effects of murine-derived anti-methamphetamine monoclonal antibodies on (+)-methamphetamine self-administration in the rat

Pharmacotherapies for Treatment of Cocaine Abuse: Preclinical Aspects

Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice

An investigation of bupropion substitution for the interoceptive stimulus effects of nicotine

Effects of the monoamine uptake inhibitors RTI-112 and RTI-113 on cocaine- and food-maintained responding in rhesus monkeys

Effect of nicotine and alpha‐7 nicotinic modulators on visceral pain‐induced conditioned place aversion in mice

Identification of the First trans-(3R,4R)- Dimethyl-4-(3-hydroxyphenyl)piperidine Derivative To Possess Highly Potent and Selective Opioid κ Receptor Antagonist Activity

Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2-exo-2-(2‘-Substituted 5‘-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine Analogues

In vivo pharmacological interactions between a type II positive allosteric modulator of [alpha]7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model

Anti‐nociception mediated by a κ opioid receptor agonist is blocked by a δ receptor agonist

Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse

Structure–activity relationship of trihexyphenidyl analogs with respect to the dopamine transporter in the on going search for a cocaine inhibitor

Effects of the specific alpha 4 beta 2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice

Cocaine and 3β-(4'-substituted phenyl)tropane-2β-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter

Synthesis and Nicotinic Acetylcholine Receptor Binding Properties of exo-2-(2‘-Fluoro-5‘-pyridinyl)-7-azabicyclo- [2.2.1]heptane: A New Positron Emission Tomography Ligand for Nicotinic Receptors

Self-administration of cocaine and the cocaine analog RTI-113: Relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys

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