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Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria

Blood, 2000-11, Vol.96 (10), p.3537-3543

2000

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Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells

JNCI : Journal of the National Cancer Institute, 2000-02, Vol.92 (3), p.217-224

2000

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2-Chlorodeoxyadenosine treatment of low-grade lymphomas

Journal of clinical oncology, 1992-03, Vol.10 (3), p.371-377

1992

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Relationship of Deoxycytidine Kinase and Cytoplasmic 5’-Nucleotidase to the Chemotherapeutic Efficacy of 2-Chlorodeoxyadenosine

Blood, 1993-02, Vol.81 (3), p.597-601

1993

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Lasting Remissions in Hairy-Cell Leukemia Induced by a Single Infusion of 2-Chlorodeoxyadenosine

The New England journal of medicine, 1990-04, Vol.322 (16), p.1117-1121

1990

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Oral Antilymphocyte Activity and Induction of Apoptosis by 2-Chloro-2'- Arabino-Fluoro-2'-Deoxyadenosine

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (7), p.2970-2974

1992

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Rational design, synthesis and structure–activity relationships of antitumor ( E)-2-benzylidene-1-tetralones and ( E)-2-benzylidene-1-indanones

Bioorganic & medicinal chemistry letters, 2000-03, Vol.10 (5), p.487-490

2000

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Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes

The Journal of clinical investigation, 1985-02, Vol.75 (2), p.377-383

1985

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Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro

Cancer research (Chicago, Ill.), 1999-04, Vol.59 (7), p.1492-1497

1999

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Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo : a novel approach to immunosuppressive therapy

The Journal of clinical investigation, 1990-11, Vol.86 (5), p.1480-1488

1990

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Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells

Cancer research (Chicago, Ill.), 1996-12, Vol.56 (24), p.5653-5658

1996

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Presence of methylthioadenosine phosphorylase (MTAP) in hematopoietic stem/progenitor cells: its therapeutic implication for MTAP (-) malignancies

Clinical cancer research, 1997-03, Vol.3 (3), p.433-438

1997

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Nucleotide Requirements for the in Vitro Activation of the Apoptosis Protein-activating Factor-1-mediated Caspase Pathway

The Journal of biological chemistry, 2000-01, Vol.275 (1), p.29-34

2000

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2-Chlorodeoxyadenosine: An Effective New Agent for the Treatment of Chronic Lymphocytic Leukemia

Blood, 1988-09, Vol.72 (3), p.1069-1073

1988

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Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2‘,3‘-dideoxyadenosine derivatives

The Journal of biological chemistry, 1988-04, Vol.263 (12), p.5870-5875

1988

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2-Chlorodeoxyadenosine: An Active Agent in the Treatment of Cutaneous T-Cell Lymphoma

Blood, 1992-08, Vol.80 (3), p.587-592

1992

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2-Chlorodeoxyadenosine dose escalation in nonhematologic malignancies

Journal of clinical oncology, 1993-04, Vol.11 (4), p.671-678

1993

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DNA strand breaks, NAD metabolism, and programmed cell death

Experimental cell research, 1986-06, Vol.164 (2), p.273-281

1986

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2-Chlorodeoxyadenosine Treatment of Refractory Chronic Lymphocytic Leukemia

Leukemia & lymphoma, 1991, Vol.5 (S1), p.133-138

1991

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Induction of an Apoptotic Program in Cell-Free Extracts by 2-Chloro-2′-deoxyadenosine 5′-Triphosphate and Cytochrome c

Proceedings of the National Academy of Sciences - PNAS, 1998-08, Vol.95 (16), p.9567-9571

1998

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A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer

Oncogene, 2000-11, Vol.19 (50), p.5747-5754

2000

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Liver transplantation from a donor with multidrug-resistant Acinetobacter baumannii infection. Is it a risk?

Revista de Gastroenterología de México (English Edition), 2023-10, Vol.88 (4), p.436-439

2023

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Marrow suppression produced by repeated doses of cladribine

Acta haematologica, 1994, Vol.91 (1), p.10-15

1994

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Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes

The Journal of immunology (1950), 1986-04, Vol.136 (8), p.2839-2843

1986

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Quantitative immunoassay of human deoxycytidine kinase in malignant cells

Analytical biochemistry, 1992-11, Vol.207 (1), p.193-196

1992

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Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria

Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells

2-Chlorodeoxyadenosine treatment of low-grade lymphomas

Relationship of Deoxycytidine Kinase and Cytoplasmic 5’-Nucleotidase to the Chemotherapeutic Efficacy of 2-Chlorodeoxyadenosine

Lasting Remissions in Hairy-Cell Leukemia Induced by a Single Infusion of 2-Chlorodeoxyadenosine

Oral Antilymphocyte Activity and Induction of Apoptosis by 2-Chloro-2'- Arabino-Fluoro-2'-Deoxyadenosine

Rational design, synthesis and structure–activity relationships of antitumor ( E)-2-benzylidene-1-tetralones and ( E)-2-benzylidene-1-indanones

Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes

Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro

Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo : a novel approach to immunosuppressive therapy

Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells

Presence of methylthioadenosine phosphorylase (MTAP) in hematopoietic stem/progenitor cells: its therapeutic implication for MTAP (-) malignancies

Nucleotide Requirements for the in Vitro Activation of the Apoptosis Protein-activating Factor-1-mediated Caspase Pathway

2-Chlorodeoxyadenosine: An Effective New Agent for the Treatment of Chronic Lymphocytic Leukemia

Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2‘,3‘-dideoxyadenosine derivatives

2-Chlorodeoxyadenosine: An Active Agent in the Treatment of Cutaneous T-Cell Lymphoma

2-Chlorodeoxyadenosine dose escalation in nonhematologic malignancies

DNA strand breaks, NAD metabolism, and programmed cell death

2-Chlorodeoxyadenosine Treatment of Refractory Chronic Lymphocytic Leukemia

Induction of an Apoptotic Program in Cell-Free Extracts by 2-Chloro-2′-deoxyadenosine 5′-Triphosphate and Cytochrome c

A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer

Liver transplantation from a donor with multidrug-resistant Acinetobacter baumannii infection. Is it a risk?

Marrow suppression produced by repeated doses of cladribine

Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes

Quantitative immunoassay of human deoxycytidine kinase in malignant cells

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