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Fragment-based lead discovery: leads by design

Drug discovery today, 2005-07, Vol.10 (14), p.987-992

2005

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Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1124-1132

2007

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Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.414-426

2005

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Enolate bromination in 2-acyl-1,3-dithiane 1-oxides

Tetrahedron, 1995-01, Vol.51 (4), p.1285-1294

1995

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A photolabile carbamate based dual linker analytical construct for facile monitoring of solid phase chemistry: ‘TLC’ for solid phase?

Tetrahedron letters, 1999-03, Vol.40 (12), p.2407-2410

1999

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Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity. 1. Optimization of the Agonist “Trigger”

Journal of medicinal chemistry, 1996-01, Vol.39 (2), p.562-569

1996

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Reporter Resins for Solid-Phase Chemistry

Organic letters, 2001-02, Vol.3 (4), p.507-510

2001

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Rapid reaction scanning of solid phase chemistry using resins incocorporating analytical constructs

Tetrahedron letters, 1999-07, Vol.40 (30), p.5609-5612

1999

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High diastereofacial selectivity in asymmetric Mannich reaction of acyldithiane oxide enolates

Journal of organic chemistry, 1993-11, Vol.58 (24), p.6902-6904

1993

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Enantioselective synthesis of (R)-(−)-2,6-dimethyl heptanoic acid: The first application of the DITOX asymmetric building block

Tetrahedron letters, 1994-04, Vol.35 (16), p.2607-2608

1994

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Diastereoselective electrophilic amination of ketone enolates in 2-substituted 2-acyl-1,3-dithiane 1-oxides

Tetrahedron letters, 1994-04, Vol.35 (15), p.2427-2430

1994

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Synthesis and reactions of derivatives of 1,7-dioxaspiro[5.5]undec-2-en-4-one

Journal of organic chemistry, 1986-10, Vol.51 (22), p.4254-4260

1986

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Solid-Phase Development of a 1-Hydroxybenzotriazole Linker for Heterocycle Synthesis Using Analytical Constructs

Journal of combinatorial chemistry, 2001-07, Vol.3 (4), p.387-396

2001

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Total synthesis of (+)-milbemycin β3

Journal of the Chemical Society. Chemical communications, 1986 (6), p.479-481

1986

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Single Bead Characterization Using Analytical Constructs: Application to Quality Control of Libraries

Analytical chemistry (Washington), 2001-03, Vol.73 (5), p.963-970

2001

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Fragment-based lead discovery: leads by design

Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase

Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation

Enolate bromination in 2-acyl-1,3-dithiane 1-oxides

A photolabile carbamate based dual linker analytical construct for facile monitoring of solid phase chemistry: ‘TLC’ for solid phase?

Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity. 1. Optimization of the Agonist “Trigger”

Reporter Resins for Solid-Phase Chemistry

Rapid reaction scanning of solid phase chemistry using resins incocorporating analytical constructs

High diastereofacial selectivity in asymmetric Mannich reaction of acyldithiane oxide enolates

Enantioselective synthesis of (R)-(−)-2,6-dimethyl heptanoic acid: The first application of the DITOX asymmetric building block

Diastereoselective electrophilic amination of ketone enolates in 2-substituted 2-acyl-1,3-dithiane 1-oxides

Synthesis and reactions of derivatives of 1,7-dioxaspiro[5.5]undec-2-en-4-one

Solid-Phase Development of a 1-Hydroxybenzotriazole Linker for Heterocycle Synthesis Using Analytical Constructs

Total synthesis of (+)-milbemycin β3

Single Bead Characterization Using Analytical Constructs: Application to Quality Control of Libraries

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