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Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1124-1132

2007

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Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery

Journal of medicinal chemistry, 2007-05, Vol.50 (10), p.2293-2296

2007

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Fragment-based lead discovery: leads by design

Drug discovery today, 2005-07, Vol.10 (14), p.987-992

2005

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Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.5912-5925

2007

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Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.414-426

2005

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Single Bead Characterization Using Analytical Constructs: Application to Quality Control of Libraries

Analytical chemistry (Washington), 2001-03, Vol.73 (5), p.963-970

2001

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Synthesis and SAR of New 5-Phenyl-3-ureido-1,5-benzodiazepines as Cholecystokinin-B Receptor Antagonists

Journal of medicinal chemistry, 2000-10, Vol.43 (20), p.3596-3613

2000

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Abstract 2635: N-Myristolytransferase (NMT) inhibitors as novel potent payloads for antibody drug conjugates

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2635-2635

2023

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Reporter Resins for Solid-Phase Chemistry

Organic letters, 2001-02, Vol.3 (4), p.507-510

2001

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High diastereofacial selectivity in asymmetric Mannich reaction of acyldithiane oxide enolates

Journal of organic chemistry, 1993-11, Vol.58 (24), p.6902-6904

1993

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Synthesis and SAR of New 5-Phenyl-3-ureido-1,5-benzodiazepines as Cholecystokinin-B Receptor Antagonists

Journal of medicinal chemistry, 2000-12, Vol.43 (26), p.5057-5057

2000

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Synthesis and reactions of derivatives of 1,7-dioxaspiro[5.5]undec-2-en-4-one

Journal of organic chemistry, 1986-10, Vol.51 (22), p.4254-4260

1986

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Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity. 1. Optimization of the Agonist “Trigger”

Journal of medicinal chemistry, 1996-01, Vol.39 (2), p.562-569

1996

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Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.414-426

2005

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Solid-Phase Development of a 1-Hydroxybenzotriazole Linker for Heterocycle Synthesis Using Analytical Constructs

Journal of combinatorial chemistry, 2001-07, Vol.3 (4), p.387-396

2001

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Total synthesis of (+)-milbemycin .beta.3

Journal of organic chemistry, 1986-12, Vol.51 (25), p.4840-4856

1986

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Total synthesis of (+)-milbemycin β3

Journal of organic chemistry, 1986, Vol.51 (25), p.4840-4856

1986

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Total synthesis of (+)-milbemycin β3

Journal of the Chemical Society. Chemical communications, 1986 (6), p.479-481

1986

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Total synthesis of (+)-milbemycin β 3

Journal of the Chemical Society. Chemical communications, 1986-03 (6), p.479-481

1986

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Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression

Nature communications, 2014-07, Vol.5 (1), p.4294-4294, Article 4294

2014

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Noninvasive Immunometabolic Cardiac Inflammation Imaging Using Hyperpolarized Magnetic Resonance

Circulation research, 2018-04, Vol.122 (8), p.1084-1093

2018

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Mental Health Public Stigma in US Jewish Communities

The journal of nervous and mental disease, 2023-02, Vol.211 (2), p.131-140

2023

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A ‘Rule of Three’ for fragment-based lead discovery?

Drug discovery today, 2003-10, Vol.8 (19), p.876-877

2003

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Donning a New Approach to the Practice of Gastroenterology: Perspectives From the COVID-19 Pandemic Epicenter

Clinical gastroenterology and hepatology, 2020-07, Vol.18 (8), p.1673-1681

2020

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Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1

PLoS medicine, 2004-10, Vol.1 (1), p.e19-e19

2004

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Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase

Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery

Fragment-based lead discovery: leads by design

Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation

Single Bead Characterization Using Analytical Constructs: Application to Quality Control of Libraries

Synthesis and SAR of New 5-Phenyl-3-ureido-1,5-benzodiazepines as Cholecystokinin-B Receptor Antagonists

Abstract 2635: N-Myristolytransferase (NMT) inhibitors as novel potent payloads for antibody drug conjugates

Reporter Resins for Solid-Phase Chemistry

High diastereofacial selectivity in asymmetric Mannich reaction of acyldithiane oxide enolates

Synthesis and SAR of New 5-Phenyl-3-ureido-1,5-benzodiazepines as Cholecystokinin-B Receptor Antagonists

Synthesis and reactions of derivatives of 1,7-dioxaspiro[5.5]undec-2-en-4-one

Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity. 1. Optimization of the Agonist “Trigger”

Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation

Solid-Phase Development of a 1-Hydroxybenzotriazole Linker for Heterocycle Synthesis Using Analytical Constructs

Total synthesis of (+)-milbemycin .beta.3

Total synthesis of (+)-milbemycin β3

Total synthesis of (+)-milbemycin β3

Total synthesis of (+)-milbemycin β 3

Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression

Noninvasive Immunometabolic Cardiac Inflammation Imaging Using Hyperpolarized Magnetic Resonance

Mental Health Public Stigma in US Jewish Communities

A ‘Rule of Three’ for fragment-based lead discovery?

Donning a New Approach to the Practice of Gastroenterology: Perspectives From the COVID-19 Pandemic Epicenter

Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1

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