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International Trade Law Statutes and Conventions 2013-2015

3rd edition., 2014

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Synthesis, biological evaluation, structural–activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators

Bioorganic & medicinal chemistry, 2008-11, Vol.16 (21), p.9554-9573

2008

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Design, Synthesis and Biochemical Evaluation of Novel Selective Estrogen Receptor Ligand Conjugates Incorporating an Endoxifen-Combretastatin Hybrid Scaffold

Biomedicines, 2016-07, Vol.4 (3), p.15

2016

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Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.514-534

2018

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Synthesis and toxicity towards normal and cancer cell lines of benzimidazolequinones containing fused aromatic rings and 2-aromatic ring substituents

European journal of medicinal chemistry, 2010-09, Vol.45 (9), p.3762-3769

2010

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Synthesis and Evaluation of Azetidinone Analogues of Combretastatin A-4 as Tubulin Targeting Agents

Journal of medicinal chemistry, 2010-12, Vol.53 (24), p.8569-8584

2010

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β‑Lactam Estrogen Receptor Antagonists and a Dual-Targeting Estrogen Receptor/Tubulin Ligand

Journal of medicinal chemistry, 2014-11, Vol.57 (22), p.9370-9382

2014

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Optimisation of estrogen receptor subtype-selectivity of a 4-Aryl-4H-chromene scaffold previously identified by virtual screening

Bioorganic & medicinal chemistry, 2020-03, Vol.28 (5), p.115261-115261, Article 115261

2020

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Lead identification of conformationally restricted β-lactam type combretastatin analogues: Synthesis, antiproliferative activity and tubulin targeting effects

European journal of medicinal chemistry, 2010-12, Vol.45 (12), p.5752-5766

2010

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“True” AntiandrogensSelective Non-Ligand-Binding Pocket Disruptors of Androgen Receptor–Coactivator Interactions: Novel Tools for Prostate Cancer

Journal of medicinal chemistry, 2012-02, Vol.55 (4), p.1635-1644

2012

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Combretastatin (CA)-4 and its novel analogue CA-432 impair T-cell migration through the Rho/ROCK signalling pathway

Biochemical pharmacology, 2014-12, Vol.92 (4), p.544-557

2014

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Synthesis, biochemical and molecular modelling studies of antiproliferative azetidinones causing microtubule disruption and mitotic catastrophe

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.4595-4607

2011

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The influence of the aziridinyl substituent of benzimidazoles and benzimidazolequinones on toxicity towards normal and Fanconi anaemia cells

European journal of medicinal chemistry, 2010-05, Vol.45 (5), p.1873-1879

2010

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Development of the β-lactam type molecular scaffold for selective estrogen receptor α modulator action: synthesis and cytotoxic effects in MCF-7 breast cancer cells

Journal of enzyme inhibition and medicinal chemistry, 2016-11, Vol.31 (sup3), p.117-130

2016

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The Vascular Targeting Agent Combretastatin-A4 and a Novel cis -Restricted β-Lactam Analogue, CA-432, Induce Apoptosis in Human Chronic Myeloid Leukemia Cells and Ex Vivo Patient Samples Including Those Displaying Multidrug Resistance

The Journal of pharmacology and experimental therapeutics, 2010-11, Vol.335 (2), p.302-313

2010

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Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro

Oncology reports, 2013-02, Vol.29 (2), p.585-594

2013

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Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor Modulators and Downregulators with Subtype-Specific ER[alpha] and ER[beta] Activity

Journal of the Statistical and Social Inquiry Society of Ireland, 2018-01, Vol.47, p.1

2018

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BubR1 is required for the mitotic block induced by combretastatin-A4 and a novel cis-restricted ß-lactam analogue in human cancer cells

International journal of molecular medicine, 2011-05, Vol.27 (5), p.715-723

2011

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Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects

Journal of enzyme inhibition and medicinal chemistry, 2010-04, Vol.25 (2), p.180-194

2010

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β-Lactam type molecular scaffolds for antiproliferative activity: Synthesis and cytotoxic effects in breast cancer cells

Journal of enzyme inhibition and medicinal chemistry, 2008-01, Vol.23 (5), p.668-685

2008

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The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance

The Journal of pharmacology and experimental therapeutics, 2010-11, Vol.335 (2), p.302

2010

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LYSOGENY IN STAPHYLOCOCCI

Journal of Bacteriology, 1961-12, Vol.82 (6), p.984-993

1961

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BubR1 is required for the mitotic block induced by combretastatin-A4 and a novel cis-restricted ß-lactam analogue in human cancer cells

International journal of molecular medicine, 2011-05, Vol.27 (5), p.715

2011

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The action of penicillin on staphylococci

The Journal of immunology (1950), 1946-03, Vol.52 (3), p.281-292

1946

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ChemInform Abstract: Synthesis, Biochemical and Molecular Modeling Studies of Antiproliferative Azetidinones Causing Microtubule Disruption and Mitotic Catastrophe

ChemInform, 2012-01, Vol.43 (3), p.no-no

2012

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International Trade Law Statutes and Conventions 2013-2015

Synthesis, biological evaluation, structural–activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators

Design, Synthesis and Biochemical Evaluation of Novel Selective Estrogen Receptor Ligand Conjugates Incorporating an Endoxifen-Combretastatin Hybrid Scaffold

Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity

Synthesis and toxicity towards normal and cancer cell lines of benzimidazolequinones containing fused aromatic rings and 2-aromatic ring substituents

Synthesis and Evaluation of Azetidinone Analogues of Combretastatin A-4 as Tubulin Targeting Agents

β‑Lactam Estrogen Receptor Antagonists and a Dual-Targeting Estrogen Receptor/Tubulin Ligand

Optimisation of estrogen receptor subtype-selectivity of a 4-Aryl-4H-chromene scaffold previously identified by virtual screening

Lead identification of conformationally restricted β-lactam type combretastatin analogues: Synthesis, antiproliferative activity and tubulin targeting effects

“True” AntiandrogensSelective Non-Ligand-Binding Pocket Disruptors of Androgen Receptor–Coactivator Interactions: Novel Tools for Prostate Cancer

Combretastatin (CA)-4 and its novel analogue CA-432 impair T-cell migration through the Rho/ROCK signalling pathway

Synthesis, biochemical and molecular modelling studies of antiproliferative azetidinones causing microtubule disruption and mitotic catastrophe

The influence of the aziridinyl substituent of benzimidazoles and benzimidazolequinones on toxicity towards normal and Fanconi anaemia cells

Development of the β-lactam type molecular scaffold for selective estrogen receptor α modulator action: synthesis and cytotoxic effects in MCF-7 breast cancer cells

The Vascular Targeting Agent Combretastatin-A4 and a Novel cis -Restricted β-Lactam Analogue, CA-432, Induce Apoptosis in Human Chronic Myeloid Leukemia Cells and Ex Vivo Patient Samples Including Those Displaying Multidrug Resistance

Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro

Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor Modulators and Downregulators with Subtype-Specific ER[alpha] and ER[beta] Activity

BubR1 is required for the mitotic block induced by combretastatin-A4 and a novel cis-restricted ß-lactam analogue in human cancer cells

Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects

β-Lactam type molecular scaffolds for antiproliferative activity: Synthesis and cytotoxic effects in breast cancer cells

The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance

LYSOGENY IN STAPHYLOCOCCI

BubR1 is required for the mitotic block induced by combretastatin-A4 and a novel cis-restricted ß-lactam analogue in human cancer cells

The action of penicillin on staphylococci

ChemInform Abstract: Synthesis, Biochemical and Molecular Modeling Studies of Antiproliferative Azetidinones Causing Microtubule Disruption and Mitotic Catastrophe

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