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Delivering CRISPR: a review of the challenges and approaches

Drug delivery, 2018, Vol.25 (1), p.1234-1257

2018

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Gene editing and CRISPR in the clinic: current and future perspectives

Bioscience reports, 2020-04, Vol.40 (4)

2020

Volltextzugriff (PDF)

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

Nature (London), 2002-08, Vol.418 (6897), p.562-566

2002

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Linkage between Werner Syndrome Protein and the Mre11 Complex via Nbs1

The Journal of biological chemistry, 2004-05, Vol.279 (20), p.21169-21176

2004

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Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

Cell, 2008-10, Vol.135 (1), p.97-109

2008

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Radiosensitization of head/neck sqaumous cell carcinoma by adenovirus-mediated expression of the Nbs1 protein

International journal of radiation oncology, biology, physics, 2007, Vol.67 (1), p.273-278

2007

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Llama-derived single domain antibodies specific for Abrus agglutinin

Toxins, 2011-11, Vol.3 (11), p.1405-1419

2011

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Differential Arrangements of Conserved Building Blocks among Homologs of the Rad50/Mre11 DNA Repair Protein Complex

Journal of molecular biology, 2004-06, Vol.339 (4), p.937-949

2004

Volltextzugriff (PDF)

Mechanisms of eukaryotic DNA double strand break repair

Frontiers in bioscience, 2006, Vol.11, p.1958

2006

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Structural Biochemistry and Interaction Architecture of the DNA Double-Strand Break Repair Mre11 Nuclease and Rad50-ATPase

Cell, 2001-05, Vol.105 (4), p.473-485

2001

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The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response

Cell, 1998-05, Vol.93 (3), p.477-486

1998

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Mutant Nbs1 enhances cisplatin-induced DNA damage and cytotoxicity in head and neck cancer

Otolaryngology-head and neck surgery, 2004-10, Vol.131 (4), p.477-484

2004

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Some Previously Unrecognized References to Classical Historians in Mary Wollstonecraft Shelley's The Last Man

Notes and queries, 2014-12, Vol.61 (4), p.527-530

Carney, James P

2014

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Structure-Based Design of Supercharged, Highly Thermoresistant Antibodies

Chemistry & biology, 2012-04, Vol.19 (4), p.449-455

2012

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Mre11 and Rad50 from Pyrococcus furiosus: Cloning and Biochemical Characterization Reveal an Evolutionarily Conserved Multiprotein Machine

Journal of Bacteriology, 2000-11, Vol.182 (21), p.6036-6041

2000

Volltextzugriff (PDF)

Dimerization of the Rad50 protein is independent of the conserved hook domain

Mutagenesis, 2007-07, Vol.22 (4), p.269-274

2007

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Inhibition of the 5' to 3' exonuclease activity of hEXO1 by 8-oxoguanine

Environmental and molecular mutagenesis, 2008-06, Vol.49 (5), p.388-398

2008

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MlaA, a hexameric ATPase linked to the Mre11 complex in archaeal genomes

EMBO reports, 2004-01, Vol.5 (1), p.54-59

2004

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Structural and functional analysis of Mre11-3

Nucleic acids research, 2004, Vol.32 (6), p.1886

2004

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Human Mre11/Human Rad50/Nbs1 and DNA Ligase IIIα/XRCC1 Protein Complexes Act Together in an Alternative Nonhomologous End Joining Pathway

The Journal of biological chemistry, 2011-09, Vol.286 (39), p.33845-33853

2011

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Chromosomal breakage syndromes

Current opinion in immunology, 1999-08, Vol.11 (4), p.443-447

Carney, James P

1999

Volltextzugriff (PDF)

Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype

Cancer research (Chicago, Ill.), 2006-03, Vol.66 (6), p.2907-2912

2006

Volltextzugriff (PDF)

Increasing DNA Repair Methyltransferase Levels Via Bone Marrow Stem Cell Transduction Rescues Mice from the Toxic Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a Chemotherapeutic Alkylating Agent

Proceedings of the National Academy of Sciences - PNAS, 1996-01, Vol.93 (1), p.206-210

1996

Volltextzugriff (PDF)

Structural Biology of Rad50 ATPase: ATP-Driven Conformational Control in DNA Double-Strand Break Repair and the ABC-ATPase Superfamily

Cell, 2000-06, Vol.101 (7), p.789-800

2000

Volltextzugriff (PDF)

Grave Matters: Mediating Corporeal Objects and Subjects through Mortuary Practices

M/C journal, 2016-04, Vol.19 (1)

2016

Volltextzugriff (PDF)

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Delivering CRISPR: a review of the challenges and approaches

Gene editing and CRISPR in the clinic: current and future perspectives

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

Linkage between Werner Syndrome Protein and the Mre11 Complex via Nbs1

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

Radiosensitization of head/neck sqaumous cell carcinoma by adenovirus-mediated expression of the Nbs1 protein

Llama-derived single domain antibodies specific for Abrus agglutinin

Differential Arrangements of Conserved Building Blocks among Homologs of the Rad50/Mre11 DNA Repair Protein Complex

Mechanisms of eukaryotic DNA double strand break repair

Structural Biochemistry and Interaction Architecture of the DNA Double-Strand Break Repair Mre11 Nuclease and Rad50-ATPase

The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response

Mutant Nbs1 enhances cisplatin-induced DNA damage and cytotoxicity in head and neck cancer

Some Previously Unrecognized References to Classical Historians in Mary Wollstonecraft Shelley's The Last Man

Structure-Based Design of Supercharged, Highly Thermoresistant Antibodies

Mre11 and Rad50 from Pyrococcus furiosus: Cloning and Biochemical Characterization Reveal an Evolutionarily Conserved Multiprotein Machine

Dimerization of the Rad50 protein is independent of the conserved hook domain

Inhibition of the 5' to 3' exonuclease activity of hEXO1 by 8-oxoguanine

MlaA, a hexameric ATPase linked to the Mre11 complex in archaeal genomes

Structural and functional analysis of Mre11-3

Human Mre11/Human Rad50/Nbs1 and DNA Ligase IIIα/XRCC1 Protein Complexes Act Together in an Alternative Nonhomologous End Joining Pathway

Chromosomal breakage syndromes

Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype

Increasing DNA Repair Methyltransferase Levels Via Bone Marrow Stem Cell Transduction Rescues Mice from the Toxic Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a Chemotherapeutic Alkylating Agent

Structural Biology of Rad50 ATPase: ATP-Driven Conformational Control in DNA Double-Strand Break Repair and the ABC-ATPase Superfamily

Grave Matters: Mediating Corporeal Objects and Subjects through Mortuary Practices

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