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Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain

Science translational medicine, 2019-07, Vol.11 (502)

2019

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IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression

Nature communications, 2017-05, Vol.8 (1), p.15508-16, Article 15508

2017

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Cytotoxic CD8 + T cells target citrullinated antigens in rheumatoid arthritis

Nature communications, 2023-01, Vol.14 (1), p.319-15, Article 319

2023

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Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer

Frontiers in immunology, 2018-08, Vol.9, p.1613-1613

2018

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HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization

The Journal of immunology (1950), 2013-07, Vol.191 (2), p.640-649

2013

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IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs

eLife, 2017-10, Vol.6

2017

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IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes

Nature immunology, 2020-10, Vol.21 (10), p.1219-1231

2020

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Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity

The Journal of immunology (1950), 2017-02, Vol.198 (3), p.1308-1319

2017

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The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90

Nature immunology, 2013-01, Vol.14 (1), p.72-81

2013

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Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids

Arthritis & rheumatology (Hoboken, N.J.), 2018-08, Vol.70 (8), p.1331-1342

2018

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Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis

ACS medicinal chemistry letters, 2020-07, Vol.11 (7), p.1402-1409

2020

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Abatacept Does Not Induce Direct Gene Expression Changes in Antigen-Presenting Cells

Journal of clinical immunology, 2009-07, Vol.29 (4), p.479-489

2009

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Direct association of tristetraprolin with the nucleoporin CAN/Nup214

Biochemical and biophysical research communications, 2004-03, Vol.315 (2), p.445-449

2004

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Clonally Expanded Cytotoxic CD8 +T cells Target Citrullinated Antigens In ACPA+ Rheumatoid Arthritis

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.78-78.05

2023

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Retinoid repletion of vitamin A-deficient mice restores IgG responses

The Journal of nutrition, 1992-05, Vol.122 (5), p.1062-1069

1992

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A Systemic Lupus Erythematosus Endophenotype Characterized by Increased CD8 Cytotoxic Signature Associates with Renal Involvement

ImmunoHorizons, 2017-09, Vol.1 (7), p.124-132

2017

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272 : The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone Hsp90

Cytokine (Philadelphia, Pa.), 2013-09, Vol.63 (3), p.307-307

2013

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272

Cytokine (Philadelphia, Pa.), 2013-09, Vol.63 (3), p.307

2013

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Role of EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes

Molecular and Cellular Biology, 1996-05, Vol.16 (5), p.2283-2294

1996

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Assessing the efficacy of using the Graduate Records Examination and undergraduate grade point average as tools to predict success in masters programs

Carman, Julie A

2009

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Immature stage B cells enter but do not progress beyond the early G1 phase of the cell cycle in response to antigen receptor signaling

The Journal of immunology (1950), 1996-06, Vol.156 (12), p.4562-4569

1996

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Abnormal regulation of IFN-gamma secretion in vitamin A deficiency

The Journal of immunology (1950), 1991-08, Vol.147 (4), p.1247-1252

1991

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A single autosomal gene defect severely limits IgG but not IgM responses in B lymphocyte‐deficient A/WySnJ mice

European journal of immunology, 1992-02, Vol.22 (2), p.373-379

1992

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The EGR1 protein contains a discrete transcriptional regulatory domain whose deletion results in a truncated protein that blocks EGR1-induced transcription

DNA and cell biology, 1995-07, Vol.14 (7), p.581-589

1995

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Retinoid Repletion of Vitamin A-Deficient Mice Restores IgG Responses1

The Journal of nutrition, 1992-05, Vol.122 (5), p.1062-1069

1992

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Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain

IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression

Cytotoxic CD8 + T cells target citrullinated antigens in rheumatoid arthritis

Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer

HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization

IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs

IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes

Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity

The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90

Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids

Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis

Abatacept Does Not Induce Direct Gene Expression Changes in Antigen-Presenting Cells

Direct association of tristetraprolin with the nucleoporin CAN/Nup214

Clonally Expanded Cytotoxic CD8 +T cells Target Citrullinated Antigens In ACPA+ Rheumatoid Arthritis

Retinoid repletion of vitamin A-deficient mice restores IgG responses

A Systemic Lupus Erythematosus Endophenotype Characterized by Increased CD8 Cytotoxic Signature Associates with Renal Involvement

272 : The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone Hsp90

272

Role of EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes

Assessing the efficacy of using the Graduate Records Examination and undergraduate grade point average as tools to predict success in masters programs

Immature stage B cells enter but do not progress beyond the early G1 phase of the cell cycle in response to antigen receptor signaling

Abnormal regulation of IFN-gamma secretion in vitamin A deficiency

A single autosomal gene defect severely limits IgG but not IgM responses in B lymphocyte‐deficient A/WySnJ mice

The EGR1 protein contains a discrete transcriptional regulatory domain whose deletion results in a truncated protein that blocks EGR1-induced transcription

Retinoid Repletion of Vitamin A-Deficient Mice Restores IgG Responses1

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