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HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization

The Journal of immunology (1950), 2013-07, Vol.191 (2), p.640-649

2013

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IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression

Nature communications, 2017-05, Vol.8 (1), p.15508-15508, Article 15508

2017

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Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer

Frontiers in immunology, 2018-08, Vol.9, p.1613-1613

2018

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Cytotoxic CD8 + T cells target citrullinated antigens in rheumatoid arthritis

Nature communications, 2023-01, Vol.14 (1), p.319-319, Article 319

2023

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TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation

The Journal of clinical investigation, 2018-12, Vol.128 (12), p.5399-5412

2018

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IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes

Nature immunology, 2020-10, Vol.21 (10), p.1219

2020

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IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis

The Journal of immunology (1950), 2017-12, Vol.199 (11), p.3849-3857

2017

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Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity

The Journal of immunology (1950), 2017-02, Vol.198 (3), p.1308-1319

2017

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The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90

Nature immunology, 2013-01, Vol.14 (1), p.72

2013

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The Transcriptome of Paired Major and Minor Salivary Gland Tissue in Patients With Primary Sjögren’s Syndrome

Frontiers in immunology, 2021-07, Vol.12, p.681941-681941

2021

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Act1 is a negative regulator in T and B cells via direct inhibition of STAT3

Nature communications, 2018-07, Vol.9 (1), p.2745-14, Article 2745

2018

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Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids

Arthritis & rheumatology (Hoboken, N.J.), 2018-08, Vol.70 (8), p.1331-1342

2018

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IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs

eLife, 2017-10, Vol.6

2017

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PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial

BMJ open, 2022-06, Vol.12 (6), p.e063424-e063424

2022

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Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis

ACS medicinal chemistry letters, 2020-07, Vol.11 (7), p.1402-1409

2020

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Comment on: Polonsky et al. Structured self-monitoring of blood glucose significantly reduces A1C levels in poorly controlled, noninsulin-treated type 2 diabetes: results from the structured testing program study. Diabetes Care 2011;34:262-267

Diabetes care, 2011-05, Vol.34 (5), p.e57; author reply e58-e57

2011

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Abatacept Does Not Induce Direct Gene Expression Changes in Antigen-Presenting Cells

Journal of clinical immunology, 2009-07, Vol.29 (4), p.479-489

2009

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Direct association of tristetraprolin with the nucleoporin CAN/Nup214

Biochemical and biophysical research communications, 2004-03, Vol.315 (2), p.445-449

2004

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Clonally Expanded Cytotoxic CD8 +T cells Target Citrullinated Antigens In ACPA+ Rheumatoid Arthritis

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.78-78.05

2023

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IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility

The Journal of immunology (1950), 2019-03, Vol.202 (5), p.1540-1548

2019

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Inactivation of the Enzyme GSK3α by the Kinase IKKi Promotes AKT-mTOR Signaling Pathway that Mediates Interleukin-1-Induced Th17 Cell Maintenance

Immunity (Cambridge, Mass.), 2012-11, Vol.37 (5), p.800-812

2012

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Abstract 2707: Integrated analysis of colorectal carcinoma by co-extraction of RNA, DNA and protein from FFPE tumor samples

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2707-2707

2018

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Abstract 5792: Preclinical antitumor activity of BMS-986158, an oral BET inhibitor, for the treatment of cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5792-5792

2018

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Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors

Bioorganic & medicinal chemistry letters, 2017-11, Vol.27 (21), p.4908-4913

2017

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HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization

IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression

Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer

Cytotoxic CD8 + T cells target citrullinated antigens in rheumatoid arthritis

TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation

IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes

IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis

Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity

The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90

The Transcriptome of Paired Major and Minor Salivary Gland Tissue in Patients With Primary Sjögren’s Syndrome

Act1 is a negative regulator in T and B cells via direct inhibition of STAT3

Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids

IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs

PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial

Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis

Comment on: Polonsky et al. Structured self-monitoring of blood glucose significantly reduces A1C levels in poorly controlled, noninsulin-treated type 2 diabetes: results from the structured testing program study. Diabetes Care 2011;34:262-267

Abatacept Does Not Induce Direct Gene Expression Changes in Antigen-Presenting Cells

Direct association of tristetraprolin with the nucleoporin CAN/Nup214

Clonally Expanded Cytotoxic CD8 +T cells Target Citrullinated Antigens In ACPA+ Rheumatoid Arthritis

IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility

Inactivation of the Enzyme GSK3α by the Kinase IKKi Promotes AKT-mTOR Signaling Pathway that Mediates Interleukin-1-Induced Th17 Cell Maintenance

Abstract 2707: Integrated analysis of colorectal carcinoma by co-extraction of RNA, DNA and protein from FFPE tumor samples

Abstract 5792: Preclinical antitumor activity of BMS-986158, an oral BET inhibitor, for the treatment of cancer

Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors

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