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Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH)

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (18), p.7379-7384

2011

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In vitro and in vivo pharmacokinetic characterization of mavacamten, a first-in-class small molecule allosteric modulator of beta cardiac myosin

Xenobiotica, 2019-06, Vol.49 (6), p.718-733

2019

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Metabolite Profiling and Reaction Phenotyping for the in Vitro Assessment of the Bioactivation of Bromfenac

Chemical research in toxicology, 2020-01, Vol.33 (1), p.249-257

2020

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Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations

Archives of biochemistry and biophysics, 2003-02, Vol.410 (1), p.16-24

2003

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Structure guided design of a series of sphingosine kinase (SphK) inhibitors

Bioorganic & medicinal chemistry letters, 2013-08, Vol.23 (16), p.4608-4616

2013

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Discovery of AMG 925, a FLT3 and CDK4 Dual Kinase Inhibitor with Preferential Affinity for the Activated State of FLT3

Journal of medicinal chemistry, 2014-04, Vol.57 (8), p.3430-3449

2014

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A three-year clinical evaluation of two dentin bonding agents

The Journal of the American Dental Association (1939), 2004-04, Vol.135 (4), p.451-457

2004

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MS(M), an efficient workflow for metabolite identification using hybrid linear ion trap Orbitrap mass spectrometer

Journal of the American Society for Mass Spectrometry, 2012-05, Vol.23 (5), p.880

2012

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An infinitary extension of the Graham--Rothschild Parameter Sets Theorem

Transactions of the American Mathematical Society, 2006-07, Vol.358 (7), p.3239-3262

2006

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Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2492-2496

2011

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Reagent-free LC-MS/MS-based pharmacokinetic quantification of polyhistidine-tagged therapeutic proteins

Bioanalysis, 2017-02, Vol.9 (3), p.251-264

2017

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Recent advances in high throughput screening for ADME properties

Combinatorial chemistry & high throughput screening, 2008-03, Vol.11 (3), p.258-264

2008

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MSM, an Efficient Workflow for Metabolite Identification Using Hybrid Linear Ion Trap Orbitrap Mass Spectrometer

Journal of the American Society for Mass Spectrometry, 2012-05, Vol.23 (5), p.880-888

2012

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On the conservativity of the axiom of choice over set theory

Archive for mathematical logic, 2011-11, Vol.50 (7-8), p.777-790

Carlson, Timothy J.

2011

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Normal forms for elementary patterns

The Journal of symbolic logic, 2012-03, Vol.77 (1), p.174-194

2012

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Development of a robust and sensitive LC–MS/MS method for the determination of adenine in plasma of different species and its application to in vivo studies

Journal of pharmaceutical and biomedical analysis, 2011-12, Vol.56 (4), p.778-784

2011

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Metabolism-guided discovery of a potent and orally bioavailable urea-based calcimimetic for the treatment of secondary hyperparathyroidism

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (24), p.6625-6628

2013

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Clinical evaluation of in-office and at-home bleaching treatments

Operative dentistry, 2003-03, Vol.28 (2), p.114

2003

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High Confidence Predictions of Drug−Drug Interactions: Predicting Affinities for Cytochrome P450 2C9 with Multiple Computational Methods

Journal of medicinal chemistry, 2008-02, Vol.51 (3), p.648-654

2008

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Application of DBS sampling in combination with LC-MS/MS for pharmacokinetic evaluation of a compound with species-specific blood-to-plasma partitioning

Bioanalysis, 2012-08, Vol.4 (16), p.2037-2047

2012

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Elementary patterns of resemblance

Annals of pure and applied logic, 2001-03, Vol.108 (1), p.19-77

J. Carlson, Timothy

2001

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Studies using structural analogs and inbred strain differences to support a role for quinone methide metabolites of butylated hydroxytoluene (BHT) in mouse lung tumor promotion

Toxicology (Amsterdam), 2001-03, Vol.160 (1), p.197-205

2001

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Academy of Operative Dentistry Award of Excellence

Operative dentistry, 2011-01, Vol.36 (1), p.118-118

Carlson, Timothy J.

2011

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Ranked partial structures

The Journal of symbolic logic, 2003-12, Vol.68 (4), p.1109-1144

Carlson, Timothy J.

2003

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Patterns of resemblance of order 2

Annals of pure and applied logic, 2009-03, Vol.158 (1), p.90-124

Carlson, Timothy J.

2009

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Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH)

In vitro and in vivo pharmacokinetic characterization of mavacamten, a first-in-class small molecule allosteric modulator of beta cardiac myosin

Metabolite Profiling and Reaction Phenotyping for the in Vitro Assessment of the Bioactivation of Bromfenac

Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations

Structure guided design of a series of sphingosine kinase (SphK) inhibitors

Discovery of AMG 925, a FLT3 and CDK4 Dual Kinase Inhibitor with Preferential Affinity for the Activated State of FLT3

A three-year clinical evaluation of two dentin bonding agents

MS(M), an efficient workflow for metabolite identification using hybrid linear ion trap Orbitrap mass spectrometer

An infinitary extension of the Graham--Rothschild Parameter Sets Theorem

Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors

Reagent-free LC-MS/MS-based pharmacokinetic quantification of polyhistidine-tagged therapeutic proteins

Recent advances in high throughput screening for ADME properties

MSM, an Efficient Workflow for Metabolite Identification Using Hybrid Linear Ion Trap Orbitrap Mass Spectrometer

On the conservativity of the axiom of choice over set theory

Normal forms for elementary patterns

Development of a robust and sensitive LC–MS/MS method for the determination of adenine in plasma of different species and its application to in vivo studies

Metabolism-guided discovery of a potent and orally bioavailable urea-based calcimimetic for the treatment of secondary hyperparathyroidism

Clinical evaluation of in-office and at-home bleaching treatments

High Confidence Predictions of Drug−Drug Interactions: Predicting Affinities for Cytochrome P450 2C9 with Multiple Computational Methods

Application of DBS sampling in combination with LC-MS/MS for pharmacokinetic evaluation of a compound with species-specific blood-to-plasma partitioning

Elementary patterns of resemblance

Studies using structural analogs and inbred strain differences to support a role for quinone methide metabolites of butylated hydroxytoluene (BHT) in mouse lung tumor promotion

Academy of Operative Dentistry Award of Excellence

Ranked partial structures

Patterns of resemblance of order 2

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