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The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

The Journal of immunology (1950), 2017-07, Vol.199 (2), p.718-733

2017

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Bile Acid Signaling in Inflammatory Bowel Diseases

Digestive diseases and sciences, 2021-03, Vol.66 (3), p.674-693

2021

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Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1

PloS one, 2015-11, Vol.10 (11), p.e0141082-e0141082

2015

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Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

Frontiers in chemistry, 2020-10, Vol.8, p.572885-572885

2020

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The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy

The FASEB journal, 2021-01, Vol.35 (1), p.e21271-n/a

2021

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The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation

PloS one, 2013-01, Vol.8 (1), p.e54472

2013

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Bile Acids Activated Receptors in Inflammatory Bowel Disease

Cells (Basel, Switzerland), 2021-05, Vol.10 (6), p.1281

2021

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Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties

Nutrients, 2019-02, Vol.11 (2), p.325

2019

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Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation

Nutrients, 2020-06, Vol.12 (7), p.1945

2020

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Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists

Scientific reports, 2016-01, Vol.6 (1), p.19008-19008, Article 19008

2016

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Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1

Scientific reports, 2019-02, Vol.9 (1), p.2504-2504, Article 2504

2019

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Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential

Frontiers in oncology, 2021-05, Vol.11, p.663771-663771

2021

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Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity

Frontiers in pharmacology, 2017-07, Vol.8, p.505-505

2017

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Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists

ACS medicinal chemistry letters, 2019-04, Vol.10 (4), p.504-510

2019

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Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

Nutrients, 2019-05, Vol.11 (5), p.1132

2019

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Bile acids and their receptors in metabolic disorders

Progress in lipid research, 2021-04, Vol.82, p.101094-101094, Article 101094

2021

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Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties

Molecules (Basel, Switzerland), 2019-03, Vol.24 (6), p.1043

2019

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Chemical and sensorial characterization of Tejate, a Mexican traditional maize-cocoa beverage, and improvement of its nutritional value by protein addition

Journal of food science and technology, 2021-09, Vol.58 (9), p.3548-3560

2021

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Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands

Scientific reports, 2016-07, Vol.6 (1), p.29320-29320, Article 29320

2016

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Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases

Frontiers in pharmacology, 2017-03, Vol.8, p.162-162

2017

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Phallusiasterol C, A New Disulfated Steroid from the Mediterranean Tunicate Phallusia fumigata

Marine drugs, 2016-06, Vol.14 (6), p.117

2016

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The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2

PloS one, 2014-04, Vol.9 (4), p.e94798

2014

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Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis

Marine drugs, 2013-12, Vol.12 (1), p.36-53

2013

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Signaling from Intestine to the Host: How Bile Acids Regulate Intestinal and Liver Immunity

Bile Acids and Their Receptors, 2019, Vol.256, p.95-108

2019

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The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

Bile Acid Signaling in Inflammatory Bowel Diseases

Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1

Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation

Bile Acids Activated Receptors in Inflammatory Bowel Disease

Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties

Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation

Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists

Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1

Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential

Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity

Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists

Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions

Bile acids and their receptors in metabolic disorders

Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties

Chemical and sensorial characterization of Tejate, a Mexican traditional maize-cocoa beverage, and improvement of its nutritional value by protein addition

Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands

Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases

Phallusiasterol C, A New Disulfated Steroid from the Mediterranean Tunicate Phallusia fumigata

The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2

Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis

Signaling from Intestine to the Host: How Bile Acids Regulate Intestinal and Liver Immunity

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