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Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy

Cancer letters, 2008-09, Vol.269 (1), p.7-17

2008

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Role and mechanism of autophagy‐regulating factors in tumorigenesis and drug resistance

Asia-Pacific journal of clinical oncology, 2021-06, Vol.17 (3), p.193-208

2021

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MLN4924: a novel first-in-class inhibitor of NEDD8-activating enzyme for cancer therapy

Expert opinion on investigational drugs, 2012-10, Vol.21 (10), p.1563-1573

2012

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Targeting HSP90 for cancer therapy

British journal of cancer, 2009-05, Vol.100 (10), p.1523-1529

2009

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Mitochondrial defects in cancer

Molecular cancer, 2002-12, Vol.1 (1), p.9-9

2002

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Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance

Blood, 2007-07, Vol.110 (1), p.313-322

2007

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The relationship between repeated measurements of HbA1c and risk of coronary events among the common haptoglobin phenotype groups: the Action for Health in Diabetes (Look AHEAD) study

Cardiovascular diabetology, 2024-10, Vol.23 (1), p.356-14, Article 356

2024

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Oncolytic reovirus sensitizes multiple myeloma cells to anti-PD-L1 therapy

Leukemia, 2018-01, Vol.32 (1), p.230-233

2018

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Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications

Leukemia, 2003-08, Vol.17 (8), p.1437-1447

2003

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WTAP is a novel oncogenic protein in acute myeloid leukemia

Leukemia, 2014-05, Vol.28 (5), p.1171-1174

2014

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Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

The Journal of biological chemistry, 2003-09, Vol.278 (39), p.37832-37839

2003

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Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism

The Journal of cell biology, 2006-12, Vol.175 (6), p.913-923

2006

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Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells

Cancer research (Chicago, Ill.), 2005-12, Vol.65 (24), p.11510-11519

2005

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Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis

Cancer research (Chicago, Ill.), 2005-12, Vol.65 (24), p.11658-11666

2005

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Mechanisms of mTOR inhibitor resistance in cancer therapy

Targeted oncology, 2011-03, Vol.6 (1), p.17-27

2011

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Targeted CUL4A inhibition synergizes with cisplatin to yield long-term survival in models of head and neck squamous cell carcinoma through a DDB2-mediated mechanism

Cell death & disease, 2022-04, Vol.13 (4), p.350-13, Article 350

2022

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Autophagy inhibition enhances vorinostat‐induced apoptosis via ubiquitinated protein accumulation

Journal of cellular and molecular medicine, 2010-10, Vol.14 (10), p.2448-2459

2010

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Intensive lifestyle intervention in type 2 diabetes and risk of incident coronary artery disease for the common haptoglobin phenotypes: the Look AHEAD study

Cardiovascular diabetology, 2024-02, Vol.23 (1), p.82-82, Article 82

2024

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The NEDD8-activating enzyme inhibitor MLN4924 disrupts nucleotide metabolism and augments the efficacy of cytarabine

Clinical cancer research, 2015-01, Vol.21 (2), p.439-447

2015

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Targeting JAK/STAT Signaling Antagonizes Resistance to Oncolytic Reovirus Therapy Driven by Prior Infection with HTLV-1 in Models of T-Cell Lymphoma

Viruses, 2021-07, Vol.13 (7), p.1406

2021

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Aggresome disruption : A novel strategy to enhance bortezomib- induced apoptosis in pancreatic cancer cells

Cancer research (Chicago, Ill.), 2006-04, Vol.66 (7), p.3773-3781

2006

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Relationship Between Time-Varying Achieved High-Density Lipoprotein Cholesterol and Risk of Coronary Events Depends on Haptoglobin Phenotype Within the ACCORD Lipid Study

Journal of the American Heart Association, 2023-10, Vol.12 (19), p.e030288-e030288

2023

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Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia

Cancer research (Chicago, Ill.), 2005-01, Vol.65 (2), p.613-621

2005

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Oncolytic reovirus inhibits angiogenesis through induction of CXCL10/IP-10 and abrogation of HIF activity in soft tissue sarcomas

Oncotarget, 2017-10, Vol.8 (49), p.86769-86783

2017

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Modulating Autophagy for Therapeutic Benefit

Autophagy, 2007-09, Vol.3 (5), p.464-467

2007

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Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy

Role and mechanism of autophagy‐regulating factors in tumorigenesis and drug resistance

MLN4924: a novel first-in-class inhibitor of NEDD8-activating enzyme for cancer therapy

Targeting HSP90 for cancer therapy

Mitochondrial defects in cancer

Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance

The relationship between repeated measurements of HbA1c and risk of coronary events among the common haptoglobin phenotype groups: the Action for Health in Diabetes (Look AHEAD) study

Oncolytic reovirus sensitizes multiple myeloma cells to anti-PD-L1 therapy

Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications

WTAP is a novel oncogenic protein in acute myeloid leukemia

Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism

Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells

Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis

Mechanisms of mTOR inhibitor resistance in cancer therapy

Targeted CUL4A inhibition synergizes with cisplatin to yield long-term survival in models of head and neck squamous cell carcinoma through a DDB2-mediated mechanism

Autophagy inhibition enhances vorinostat‐induced apoptosis via ubiquitinated protein accumulation

Intensive lifestyle intervention in type 2 diabetes and risk of incident coronary artery disease for the common haptoglobin phenotypes: the Look AHEAD study

The NEDD8-activating enzyme inhibitor MLN4924 disrupts nucleotide metabolism and augments the efficacy of cytarabine

Targeting JAK/STAT Signaling Antagonizes Resistance to Oncolytic Reovirus Therapy Driven by Prior Infection with HTLV-1 in Models of T-Cell Lymphoma

Aggresome disruption : A novel strategy to enhance bortezomib- induced apoptosis in pancreatic cancer cells

Relationship Between Time-Varying Achieved High-Density Lipoprotein Cholesterol and Risk of Coronary Events Depends on Haptoglobin Phenotype Within the ACCORD Lipid Study

Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia

Oncolytic reovirus inhibits angiogenesis through induction of CXCL10/IP-10 and abrogation of HIF activity in soft tissue sarcomas

Modulating Autophagy for Therapeutic Benefit

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