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Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (25), p.E4924-E4933

2017

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ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer

PloS one, 2010-05, Vol.5 (5), p.e10547-e10547

2010

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Epigenetics in Prostate Cancer: Biologic and Clinical Relevance

European urology, 2011-10, Vol.60 (4), p.753-766

2011

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Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer

Nature communications, 2021-02, Vol.12 (1), p.734-734, Article 734

2021

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RNAi-Mediated Silencing of Myc Transcription Inhibits Stem-like Cell Maintenance and Tumorigenicity in Prostate Cancer

Cancer research (Chicago, Ill.), 2013-11, Vol.73 (22), p.6816-6827

2013

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EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer

Nature communications, 2021-07, Vol.12 (1), p.4147-4147, Article 4147

2021

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Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells

The EMBO journal, 2009-06, Vol.28 (12), p.1708-1719

2009

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Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)

Molecular oncology, 2015-06, Vol.9 (6), p.1194-1206

2015

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The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment

Oncotarget, 2016-11, Vol.7 (47), p.76756-76768

2016

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A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers

Nature communications, 2017-05, Vol.8 (1), p.15622-15622, Article 15622

2017

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Modulation of the activity of Sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancer

PloS one, 2012-04, Vol.7 (4), p.e35130

2012

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Metabolomics in oncology

Cancer reports, 2023-03, Vol.6 (3), p.e1795-n/a

2023

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Potential of miRNAs in Plasma Extracellular Vesicle for the Stratification of Prostate Cancer in a South African Population

Cancers, 2023-08, Vol.15 (15), p.3968

2023

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Detection of Cancer-Associated Gene Mutations in Urinary Cell-Free DNA among Prostate Cancer Patients in South Africa

Genes, 2023-09, Vol.14 (10), p.1884

2023

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Transcriptional and Non-Transcriptional Functions of PPARβ/δ in Non-Small Cell Lung Cancer

PloS one, 2012-09, Vol.7 (9), p.e46009

2012

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Mitochondrial Plasticity Promotes Resistance to Sorafenib and Vulnerability to STAT3 Inhibition in Human Hepatocellular Carcinoma

Cancers, 2021-11, Vol.13 (23), p.6029

2021

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Transcriptional Reprogramming and Novel Therapeutic Approaches for Targeting Prostate Cancer Stem Cells

Frontiers in oncology, 2019-05, Vol.9, p.385-385

2019

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A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors)

Cancers, 2020-01, Vol.12 (1), p.176

2020

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Erratum: Mapelli, S.N., et al. A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors). Cancers 2020, 12, 176

Cancers, 2020-10, Vol.12 (10), p.2971

2020

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Inflammatory metabolic profile of South African patients with prostate cancer

Cancer & metabolism, 2021-08, Vol.9 (1), p.1-29, Article 29

2021

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Mitochondrial fission promotes self-renewal and tumorigenic potential in prostate cancer

Molecular & cellular oncology, 2019-01, Vol.6 (5), p.e1644598-e1644598

2019

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Mechanisms of triplex DNA-mediated inhibition of transcription initiation in cells

Biochimie, 2010-03, Vol.92 (3), p.317-320

2010

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Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer

Cancer research (Chicago, Ill.), 2016-06, Vol.76 (12), p.3629-3643

2016

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Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells

Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer

ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer

Epigenetics in Prostate Cancer: Biologic and Clinical Relevance

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer

RNAi-Mediated Silencing of Myc Transcription Inhibits Stem-like Cell Maintenance and Tumorigenicity in Prostate Cancer

EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer

Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells

Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)

The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment

A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers

Modulation of the activity of Sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancer

Metabolomics in oncology

Potential of miRNAs in Plasma Extracellular Vesicle for the Stratification of Prostate Cancer in a South African Population

Detection of Cancer-Associated Gene Mutations in Urinary Cell-Free DNA among Prostate Cancer Patients in South Africa

Transcriptional and Non-Transcriptional Functions of PPARβ/δ in Non-Small Cell Lung Cancer

Mitochondrial Plasticity Promotes Resistance to Sorafenib and Vulnerability to STAT3 Inhibition in Human Hepatocellular Carcinoma

Transcriptional Reprogramming and Novel Therapeutic Approaches for Targeting Prostate Cancer Stem Cells

A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors)

Erratum: Mapelli, S.N., et al. A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors). Cancers 2020, 12, 176

Inflammatory metabolic profile of South African patients with prostate cancer

Circulating extracellular vesicles release oncogenic miR-424 in experimental models and patients with aggressive prostate cancer

Mitochondrial fission promotes self-renewal and tumorigenic potential in prostate cancer

Mechanisms of triplex DNA-mediated inhibition of transcription initiation in cells

Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer

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