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Gene Therapy Progress and Prospects. Downregulating gene expression: the impact of RNA interference

Gene therapy, 2004-08, Vol.11 (16), p.1241-1248

CAPLEN, N. J

2004

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Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes

British journal of cancer, 2008-05, Vol.98 (9), p.1515-1524

2008

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RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors

Current cancer drug targets, 2011-10, Vol.11 (8), p.976-986

2011

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Specific Inhibition of Gene Expression by Small Double-Stranded RNAs in Invertebrate and Vertebrate Systems

Proceedings of the National Academy of Sciences - PNAS, 2001-08, Vol.98 (17), p.9742-9747

2001

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Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference

Human molecular genetics, 2002-01, Vol.11 (2), p.175-184

2002

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Short Interfering RNAs Can Induce Unexpected and Divergent Changes in the Levels of Untargeted Proteins in Mammalian Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (7), p.1892-1897

2004

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Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice

Nature genetics, 1993-10, Vol.5 (2), p.135-142

1993

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The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro

Gene therapy, 1998, Vol.5 (1), p.91-98

1998

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Defining and Assaying RNAi in Mammalian Cells

Molecular cell, 2005-01, Vol.17 (1), p.1-10

2005

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RNAi microarray analysis in cultured mammalian cells

Genome research, 2003-10, Vol.13 (10), p.2341-2347

2003

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dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference

Gene, 2000-07, Vol.252 (1), p.95-105

2000

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Adeno-retroviral chimeric viruses as in vivo transducing agents

Gene therapy, 1999-03, Vol.6 (3), p.454-459

1999

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Cystic fibrosis gene therapy trials and tribulations

Trends in molecular medicine, 2001-11, Vol.7 (11), p.488-488

Caplen, Natasha J

2001

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CFTR gene transfer reduces the binding of Pseudomonas aeruginosa to cystic fibrosis respiratory epithelium

American journal of respiratory cell and molecular biology, 1997-06, Vol.16 (6), p.657-663

1997

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Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

Nature medicine, 1995-01, Vol.1 (1), p.39-46

1995

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In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE

Gene therapy, 1995-11, Vol.2 (9), p.603

1995

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Nasal application of the cationic liposome DC-Chol:DOPE does not alter ion transport, lung function or bacterial growth

The European respiratory journal, 1994-03, Vol.7 (3), p.442-445

1994

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The effects of jet nebulisation on cationic liposome-mediated gene transfer in vitro

Gene therapy, 1998-05, Vol.5 (5), p.583-593

1998

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RNAi quashes polyQ

Nature medicine, 2004-08, Vol.10 (8), p.775-776

Caplen, Natasha J

2004

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Bioelectric characteristics of exon 10 insertional cystic fibrosis mouse: comparison with humans

American Journal of Physiology: Cell Physiology, 1995-02, Vol.268 (2), p.C297-C307

1995

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Gene therapy for cystic fibrosis in humans by liposome-mediated DNA transfer: the production of resources and the regulatory process

Gene therapy, 1994-03, Vol.1 (2), p.139

1994

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Quantitative fluorescence measurements of chloride secretion in native airway epithelium from CF and non-CF subjects

Gene therapy, 1995-12, Vol.2 (10), p.766

1995

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Nucleic acid transfer using cationic lipids

Methods in molecular biology (Clifton, N.J.), 2000, Vol.133, p.1

Caplen, N J

2000

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RNAi as a gene therapy approach

Expert opinion on biological therapy, 2003-07, Vol.3 (4), p.575-586

Caplen, Natasha J

2003

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Applications of RNA interference in mammalian systems

Annual review of genomics and human genetics, 2007-01, Vol.8 (1), p.81-108

2007

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Gene Therapy Progress and Prospects. Downregulating gene expression: the impact of RNA interference

Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes

RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors

Specific Inhibition of Gene Expression by Small Double-Stranded RNAs in Invertebrate and Vertebrate Systems

Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference

Short Interfering RNAs Can Induce Unexpected and Divergent Changes in the Levels of Untargeted Proteins in Mammalian Cells

Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice

The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro

Defining and Assaying RNAi in Mammalian Cells

RNAi microarray analysis in cultured mammalian cells

dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference

Adeno-retroviral chimeric viruses as in vivo transducing agents

Cystic fibrosis gene therapy trials and tribulations

CFTR gene transfer reduces the binding of Pseudomonas aeruginosa to cystic fibrosis respiratory epithelium

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE

Nasal application of the cationic liposome DC-Chol:DOPE does not alter ion transport, lung function or bacterial growth

The effects of jet nebulisation on cationic liposome-mediated gene transfer in vitro

RNAi quashes polyQ

Bioelectric characteristics of exon 10 insertional cystic fibrosis mouse: comparison with humans

Gene therapy for cystic fibrosis in humans by liposome-mediated DNA transfer: the production of resources and the regulatory process

Quantitative fluorescence measurements of chloride secretion in native airway epithelium from CF and non-CF subjects

Nucleic acid transfer using cationic lipids

RNAi as a gene therapy approach

Applications of RNA interference in mammalian systems

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