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Artemisinin‐derived dimers from a chemical perspective

Medicinal research reviews, 2021-11, Vol.41 (6), p.2927-2970

2021

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Artemisinin-Derived Dimers: Potent Antimalarial and Anticancer Agents

Journal of medicinal chemistry, 2016-08, Vol.59 (16), p.7360-7388

2016

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Cytotoxic profiling of artesunic and betulinic acids and their synthetic hybrid compound on neurons and gliomas

Oncotarget, 2017-09, Vol.8 (37), p.61457-61474

2017

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Chemical hybridization of sulfasalazine and dihydroartemisinin promotes brain tumor cell death

Scientific reports, 2021-10, Vol.11 (1), p.20766-20766, Article 20766

2021

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Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

Angewandte Chemie International Edition, 2019-09, Vol.58 (37), p.13066-13079

International ed. in English, 2019

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Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities

Bioorganic & medicinal chemistry, 2019-01, Vol.27 (1), p.110-115

2019

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(Iso)Quinoline–Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses

Chemistry : a European journal, 2020-09, Vol.26 (52), p.12019-12026

2020

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Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells

Cell death & disease, 2019-05, Vol.10 (6), p.379, Article 379

2019

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Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide‐Based Hybrid Compounds against SARS‐CoV‐2 and Cancer

ChemMedChem, 2022-05, Vol.17 (9), p.e202200005-n/a

2022

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Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells

European journal of medicinal chemistry, 2014-03, Vol.75, p.403-412

2014

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Autofluorescent antimalarials by hybridization of artemisinin and coumarin: in vitro / in vivo studies and live-cell imaging

Chemical science (Cambridge), 2023-11, Vol.14 (45), p.12941-12952

2023

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New artesunic acid homodimers: Potent reversal agents of multidrug resistance in leukemia cells

Bioorganic & medicinal chemistry, 2012-09, Vol.20 (18), p.5637-5641

2012

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Studies of Potency and Efficacy of an Optimized Artemisinin-Quinoline Hybrid against Multiple Stages of the Plasmodium Life Cycle

Pharmaceuticals (Basel, Switzerland), 2021-11, Vol.14 (11), p.1129

2021

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Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin

Bioorganic & medicinal chemistry, 2018-07, Vol.26 (12), p.3610-3618

2018

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Target verification of artesunate-related antiviral drugs: Assessing the role of mitochondrial and regulatory proteins by click chemistry and fluorescence labeling

Antiviral research, 2020-08, Vol.180, p.104861-104861, Article 104861

2020

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Synthesis, antimicrobial and cytotoxic activities, and structure–activity relationships of gypsogenin derivatives against human cancer cells

European journal of medicinal chemistry, 2014-07, Vol.82, p.565-573

2014

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Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

Angewandte Chemie, 2019-09, Vol.131 (37), p.13200-13213

2019

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Synthesis of Substituted 1,2,3-Triazoles via Metal-Free Click Cycloaddition Reactions and Alternative Cyclization Methods

Synthesis (Stuttgart), 2017-01, Vol.49 (1), p.29-41

2017

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Back Cover Image, Volume 41, Issue 6

Medicinal research reviews, 2021-11, Vol.41 (6), p.ii-ii

2021

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Autofluorescent antimalarials by hybridization of artemisinin and coumarin: / studies and live-cell imaging

Chemical science (Cambridge), 2023-11, Vol.14 (45), p.12941-12952

2023

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Cover Feature: (Iso)Quinoline–Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses (Chem. Eur. J. 52/2020)

Chemistry : a European journal, 2020-09, Vol.26 (52), p.11912-11912

2020

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Inside Back Cover: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. Int. Ed. 37/2019)

Angewandte Chemie International Edition, 2019-09, Vol.58 (37), p.13161-13161

2019

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Abstract 1904: Novel 5-fluorouracil-thymoquinone hybrid kills colon cancer stem cells

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1904-1904

2017

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Innenrücktitelbild: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. 37/2019)

Angewandte Chemie, 2019-09, Vol.131 (37), p.13295-13295

2019

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Artemisinin‐derived dimers from a chemical perspective

Artemisinin-Derived Dimers: Potent Antimalarial and Anticancer Agents

Cytotoxic profiling of artesunic and betulinic acids and their synthetic hybrid compound on neurons and gliomas

Chemical hybridization of sulfasalazine and dihydroartemisinin promotes brain tumor cell death

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities

(Iso)Quinoline–Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses

Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells

Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide‐Based Hybrid Compounds against SARS‐CoV‐2 and Cancer

Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells

Autofluorescent antimalarials by hybridization of artemisinin and coumarin: in vitro / in vivo studies and live-cell imaging

New artesunic acid homodimers: Potent reversal agents of multidrug resistance in leukemia cells

Studies of Potency and Efficacy of an Optimized Artemisinin-Quinoline Hybrid against Multiple Stages of the Plasmodium Life Cycle

Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin

Target verification of artesunate-related antiviral drugs: Assessing the role of mitochondrial and regulatory proteins by click chemistry and fluorescence labeling

Synthesis, antimicrobial and cytotoxic activities, and structure–activity relationships of gypsogenin derivatives against human cancer cells

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

Synthesis of Substituted 1,2,3-Triazoles via Metal-Free Click Cycloaddition Reactions and Alternative Cyclization Methods

Back Cover Image, Volume 41, Issue 6

Autofluorescent antimalarials by hybridization of artemisinin and coumarin: / studies and live-cell imaging

Cover Feature: (Iso)Quinoline–Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses (Chem. Eur. J. 52/2020)

Inside Back Cover: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. Int. Ed. 37/2019)

Abstract 1904: Novel 5-fluorouracil-thymoquinone hybrid kills colon cancer stem cells

Innenrücktitelbild: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. 37/2019)

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