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Common cardiac medications potently inhibit ACE2 binding to the SARS-CoV-2 Spike, and block virus penetration and infectivity in human lung cells

Scientific reports, 2021-11, Vol.11 (1), p.22195-22195, Article 22195

2021

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Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 spike protein

Scientific reports, 2024-07, Vol.14 (1), p.16895-16, Article 16895

2024

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A Dominant-Negative Mutant of ANXA7 Impairs Calcium Signaling and Enhances the Proliferation of Prostate Cancer Cells by Downregulating the IP3 Receptor and the PI3K/mTOR Pathway

International journal of molecular sciences, 2023-05, Vol.24 (10), p.8818

2023

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Cardiac Glycosides Inhibit TNF-α/NF-κB Signaling by Blocking Recruitment of TNF Receptor-Associated Death Domain to the TNF Receptor

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (27), p.9631-9636

2005

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Protein Kinase C and Guanosine Triphosphate Combine to Potentiate Calcium-dependent Membrane Fusion Driven by Annexin 7

The Journal of biological chemistry, 2002-07, Vol.277 (28), p.25217-25225

2002

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Defects in Inositol 1,4,5-Trisphosphate Receptor Expression, Ca2+Signaling, and Insulin Secretion in the anx7(+/-) Knockout Mouse

Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (24), p.13783-13788

1999

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Rescue of ΔF508-CFTR by the SGK1/Nedd4-2 Signaling Pathway

The Journal of biological chemistry, 2009-09, Vol.284 (37), p.25241-25253

2009

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Activation of 3-Phosphoinositide-dependent Kinase 1 (PDK1) and Serum- and Glucocorticoid-induced Protein Kinase 1 (SGK1) by Short-chain Sphingolipid C4-ceramide Rescues the Trafficking Defect of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (ΔF508-CFTR)

The Journal of biological chemistry, 2014-12, Vol.289 (52), p.35953-35968

2014

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Activation of Annexin 7 by Protein Kinase C in Vitroand in Vivo

The Journal of biological chemistry, 2001-04, Vol.276 (16), p.12813-12821

2001

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Rescue of ÎF508-CFTR by the SGK1/Nedd4-2 Signaling Pathway

The Journal of biological chemistry, 2009-09, Vol.284 (37), p.25241

2009

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Digitoxin Mimics Gene Therapy with CFTR and Suppresses Hypersecretion of IL-8 from Cystic Fibrosis Lung Epithelial Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-05, Vol.101 (20), p.7693-7698

2004

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Membrane Fusion Protein Synexin (Annexin VII) as a Ca$^{2+}$/GTP Sensor in Exocytotic Secretion

Proceedings of the National Academy of Sciences - PNAS, 1996-10, Vol.93 (20), p.10797-10802

1996

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Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/-) knockout mouse

Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (24), p.13783

1999

Volltextzugriff (PDF)

Activation of annexin 7 by protein kinase C in vitro and in vivo

The Journal of biological chemistry, 2001-04, Vol.276 (16), p.12813-12821

2001

Volltextzugriff (PDF)

Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway

The Journal of biological chemistry, 2009-09, Vol.284 (37), p.25241-25253

2009

Volltextzugriff (PDF)

Amphiphilic pyridinium salts block TNFα/NFκB signaling and constitutive hypersecretion of interleukin-8 (IL-8) from cystic fibrosis lung epithelial cells

Biochemical pharmacology, 2005-08, Vol.70 (3), p.381-393

2005

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Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (27), p.9631-9636

2005

Volltextzugriff (PDF)

Membrane fusion protein synexin (annexin VII) as a Ca super(2+)/GTP sensor in exocytotic secretion

Proceedings of the National Academy of Sciences - PNAS, 1996-01, Vol.93 (20), p.10797-10802

1996

Volltextzugriff (PDF)

Defects in inositol 1,4,5-trisphosphate receptor expression, Ca 2+ signaling, and insulin secretion in the anx 7(+/−) knockout mouse

Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (24), p.13783-13788

1999

Volltextzugriff (PDF)

Novel isoforms of synexin in Xenopus laevis: multiple tandem PGQM repeats distinguish mRNAs in specific adult tissues and embryonic stages

Biochemical journal, 1996-06, Vol.316 ( Pt 3) (3), p.729-735

1996

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The Goldfish as a Drug Discovery Vehicle for Parkinson's Disease and Other Neurodegenerative Disorders

Annals of the New York Academy of Sciences, 1993-05, Vol.679 (1), p.317-320

1993

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Human synexin (annexin VII) polymorphisms: tissue specificity and expression in Escherichia coli

Biochemical Society transactions, 1990-12, Vol.18 (6), p.1118

1990

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Synexin (Annexin VII) Hypothesis for Ca2+/GTP-Regulated Exocytosis

Advances in Pharmacology, 1997, Vol.42, p.81-87

1997

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Membrane fusion protein synexin (annexin VII) as a Ca2+/GTP sensor in exocytotic secretion

Proceedings of the National Academy of Sciences - PNAS, 1996-10, Vol.93 (20), p.10797-10802

1996

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Common cardiac medications potently inhibit ACE2 binding to the SARS-CoV-2 Spike, and block virus penetration and infectivity in human lung cells

Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 spike protein

A Dominant-Negative Mutant of ANXA7 Impairs Calcium Signaling and Enhances the Proliferation of Prostate Cancer Cells by Downregulating the IP3 Receptor and the PI3K/mTOR Pathway

Cardiac Glycosides Inhibit TNF-α/NF-κB Signaling by Blocking Recruitment of TNF Receptor-Associated Death Domain to the TNF Receptor

Protein Kinase C and Guanosine Triphosphate Combine to Potentiate Calcium-dependent Membrane Fusion Driven by Annexin 7

Defects in Inositol 1,4,5-Trisphosphate Receptor Expression, Ca2+Signaling, and Insulin Secretion in the anx7(+/-) Knockout Mouse

Rescue of ΔF508-CFTR by the SGK1/Nedd4-2 Signaling Pathway

Activation of 3-Phosphoinositide-dependent Kinase 1 (PDK1) and Serum- and Glucocorticoid-induced Protein Kinase 1 (SGK1) by Short-chain Sphingolipid C4-ceramide Rescues the Trafficking Defect of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (ΔF508-CFTR)

Activation of Annexin 7 by Protein Kinase C in Vitroand in Vivo

Rescue of ÎF508-CFTR by the SGK1/Nedd4-2 Signaling Pathway

Digitoxin Mimics Gene Therapy with CFTR and Suppresses Hypersecretion of IL-8 from Cystic Fibrosis Lung Epithelial Cells

Membrane Fusion Protein Synexin (Annexin VII) as a Ca$^{2+}$/GTP Sensor in Exocytotic Secretion

Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/-) knockout mouse

Activation of annexin 7 by protein kinase C in vitro and in vivo

Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway

Amphiphilic pyridinium salts block TNFα/NFκB signaling and constitutive hypersecretion of interleukin-8 (IL-8) from cystic fibrosis lung epithelial cells

Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor

Membrane fusion protein synexin (annexin VII) as a Ca super(2+)/GTP sensor in exocytotic secretion

Defects in inositol 1,4,5-trisphosphate receptor expression, Ca 2+ signaling, and insulin secretion in the anx 7(+/−) knockout mouse

Novel isoforms of synexin in Xenopus laevis: multiple tandem PGQM repeats distinguish mRNAs in specific adult tissues and embryonic stages

The Goldfish as a Drug Discovery Vehicle for Parkinson's Disease and Other Neurodegenerative Disorders

Human synexin (annexin VII) polymorphisms: tissue specificity and expression in Escherichia coli

Synexin (Annexin VII) Hypothesis for Ca2+/GTP-Regulated Exocytosis

Membrane fusion protein synexin (annexin VII) as a Ca2+/GTP sensor in exocytotic secretion

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