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BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

Nature (London), 2015-11, Vol.527 (7577), p.192-197

2015

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High-Throughput Approaches to Pinpoint Function within the Noncoding Genome

Molecular cell, 2017-10, Vol.68 (1), p.44-59

2017

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Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

Science (American Association for the Advancement of Science), 2016-01, Vol.351 (6270), p.285-289

2016

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Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci

Proceedings of the National Academy of Sciences - PNAS, 2017-12, Vol.114 (52), p.E11257-E11266

2017

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Generation of genomic deletions in mammalian cell lines via CRISPR/Cas9

Journal of visualized experiments, 2015-01 (95), p.e52118

2015

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Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis

Nature genetics, 2019-07, Vol.51 (7), p.1149-1159

2019

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Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments

Nature protocols, 2018-05, Vol.13 (5), p.946-986

2018

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Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells

Scientific reports, 2018-05, Vol.8 (1), p.8001-10, Article 8001

2018

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Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci

Nature genetics, 2017-04, Vol.49 (4), p.625-634

2017

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EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression

Blood, 2015-10, Vol.126 (16), p.1930-1939

2015

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DrugThatGene: integrative analysis to streamline the identification of druggable genes, pathways and protein complexes from CRISPR screens

Bioinformatics (Oxford, England), 2019-06, Vol.35 (11), p.1981-1984

2019

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CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis

Genome Biology, 2018-10, Vol.19 (1), p.169-19, Article 169

2018

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Characterization of genomic deletion efficiency mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells

The Journal of biological chemistry, 2017-02, Vol.292 (6), p.2556-2556

2017

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Performance of Five Commercial Identification Platforms for Identification of Staphylococcus delphini

Journal of clinical microbiology, 2019-11, Vol.57 (11)

2019

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CRISPResso2 provides accurate and rapid genome editing sequence analysis

Nature biotechnology, 2019-03, Vol.37 (3), p.224-226

2019

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CRISPRitz: rapid, high-throughput and variant-aware in silico off-target site identification for CRISPR genome editing

Bioinformatics, 2020-04, Vol.36 (7), p.2001-2008

2020

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Analyzing CRISPR genome-editing experiments with CRISPResso

Nature biotechnology, 2016-07, Vol.34 (7), p.695-697

2016

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PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells

Cell reports (Cambridge), 2015-09, Vol.12 (9), p.1456-1470

2015

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Impact of Genetic Variation on CRISPR-Cas Targeting

CRISPR journal, 2018-04, Vol.1 (2), p.159-170

2018

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An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level

Science (American Association for the Advancement of Science), 2013-10, Vol.342 (6155), p.253-257

2013

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Customizing the genome as therapy for the β-hemoglobinopathies

Blood, 2016-05, Vol.127 (21), p.2536-2545

2016

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Characterization of Genomic Deletion Efficiency Mediated by Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas9 Nuclease System in Mammalian Cells

The Journal of biological chemistry, 2014-08, Vol.289 (31), p.21312-21324

2014

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Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype

The Journal of clinical investigation, 2016-10, Vol.126 (10), p.3868-3878

2016

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Technologies and Computational Analysis Strategies for CRISPR Applications

Molecular cell, 2020-07, Vol.79 (1), p.11-29

2020

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BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

High-Throughput Approaches to Pinpoint Function within the Noncoding Genome

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci

Generation of genomic deletions in mammalian cell lines via CRISPR/Cas9

Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis

Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments

Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression

DrugThatGene: integrative analysis to streamline the identification of druggable genes, pathways and protein complexes from CRISPR screens

CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis

Characterization of genomic deletion efficiency mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells

Performance of Five Commercial Identification Platforms for Identification of Staphylococcus delphini

CRISPResso2 provides accurate and rapid genome editing sequence analysis

CRISPRitz: rapid, high-throughput and variant-aware in silico off-target site identification for CRISPR genome editing

Analyzing CRISPR genome-editing experiments with CRISPResso

PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells

Impact of Genetic Variation on CRISPR-Cas Targeting

An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level

Customizing the genome as therapy for the β-hemoglobinopathies

Characterization of Genomic Deletion Efficiency Mediated by Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas9 Nuclease System in Mammalian Cells

Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype

Technologies and Computational Analysis Strategies for CRISPR Applications

Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling

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