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The serotonin 5-HT2C receptor and the non-addictive nature of classic hallucinogens

Journal of Psychopharmacology, 2017-01, Vol.31 (1), p.127-143

2017

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Activity of Mitragyna speciosa (“Kratom”) Alkaloids at Serotonin Receptors

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13510-13523

2021

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Amnesia produced by altered release of neurotransmitters after intraamygdala injections of a protein synthesis inhibitor

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (30), p.12500-12505

2007

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The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen

Psychopharmacologia, 2010-04, Vol.209 (2), p.163-174

2010

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“Selective” serotonin 5-HT2A receptor antagonists

Biochemical pharmacology, 2022-06, Vol.200, p.115028-115028, Article 115028

2022

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Altered brain serotonin 5-HT1A receptor expression and function in juvenile Fmr1 knockout mice

Neuropharmacology, 2024-03, Vol.245, p.109774-109774, Article 109774

2024

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Classics in Chemical Neuroscience: Aripiprazole

ACS chemical neuroscience, 2017-06, Vol.8 (6), p.1135-1146

2017

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Targeting 5-HT 1A Receptors to Correct Perineuronal Net and Social Behavioral Deficits in Fmr1 Knockout Mice, a Model of Fragile X Syndrome

The FASEB journal, 2022-05, Vol.36 Suppl 1 (S1)

2022

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The Need To Improve Reporting of the Pharmacological Action of New Molecules

ACS chemical neuroscience, 2022-01, Vol.13 (2), p.185-186

2022

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Structure-Activity Relationship Study of Psychostimulant Synthetic Cathinones Reveals Nanomolar Antagonist Potency of α-Pyrrolidinohexiophenone at Human Muscarinic M 2 Receptors

ACS chemical neuroscience, 2020-03, Vol.11 (6), p.960-968

2020

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Structure–Activity Relationship Study of Psychostimulant Synthetic Cathinones Reveals Nanomolar Antagonist Potency of α‑Pyrrolidinohexiophenone at Human Muscarinic M2 Receptors

ACS chemical neuroscience, 2020-03, Vol.11 (6), p.960-968

2020

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Serotonergic Psychedelics: Experimental Approaches for Assessing Mechanisms of Action

New Psychoactive Substances, 2018, Vol.252, p.227-260

2018

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Spontaneous seizures in adult Fmr1 knockout mice: FVB.129P2-Pde6b+Tyrc-chFmr1tm1Cgr/J

Epilepsy research, 2022-05, Vol.182, p.106891-106891, Article 106891

2022

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Spontaneous seizures in adult Fmr1 knockout mice: FVB.129P2-Pde6b+ Tyr Fmr1/J

Epilepsy research, 2022-05, Vol.182, p.106891, Article 106891

2022

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Targeting 5‐HT1A Receptors to Correct Neuronal Hyperexcitability in Fmr1 Knockout Mice

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Ligand-directed serotonin 5-HT2C receptor desensitization and sensitization

European journal of pharmacology, 2019-04, Vol.848, p.131-139

2019

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Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model

Neuropharmacology, 2013-07, Vol.70, p.112-121

2013

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Effects of the second-generation "bath salt" cathinone alpha-pyrrolidinopropiophenone (α-PPP) on behavior and monoamine neurochemistry in male mice

Psychopharmacology, 2019-03, Vol.236 (3), p.1107-1117

2019

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Synthesis and Structure–Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5‑HT2 Receptor Agonist

Journal of medicinal chemistry, 2024-04, Vol.67 (8), p.6144-6188

2024

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Synthesis and Structure-Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT 2 Receptor Agonist

Journal of medicinal chemistry, 2024-04, Vol.67 (8), p.6144-6188

2024

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The Psychedelic N,N‑Dipropyltryptamine Prevents Seizures in a Mouse Model of Fragile X Syndrome via a Mechanism that Appears Independent of Serotonin and Sigma1 Receptors

ACS pharmacology & translational science, 2023-10, Vol.6 (10), p.1480-1491

2023

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Evaluation of lorcaserin as an anticonvulsant in juvenile Fmr1 knockout mice

Epilepsy research, 2021-09, Vol.175, p.106677-106677, Article 106677

2021

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Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HT1A and 5-HT7 G protein-coupled receptor affinity, 3D-QSAR and molecular modeling

Bioorganic & medicinal chemistry, 2020-02, Vol.28 (3), p.115262, Article 115262

2020

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M100907 and BD 1047 attenuate the acute toxic effects of methamphetamine

Neurotoxicology (Park Forest South), 2019-09, Vol.74, p.91-99

2019

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NeuroChat with Professor Clinton E. Canal

ACS chemical neuroscience, 2020-11, Vol.11 (21), p.3485-3487

2020

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The serotonin 5-HT2C receptor and the non-addictive nature of classic hallucinogens

Activity of Mitragyna speciosa (“Kratom”) Alkaloids at Serotonin Receptors

Amnesia produced by altered release of neurotransmitters after intraamygdala injections of a protein synthesis inhibitor

The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen

“Selective” serotonin 5-HT2A receptor antagonists

Altered brain serotonin 5-HT1A receptor expression and function in juvenile Fmr1 knockout mice

Classics in Chemical Neuroscience: Aripiprazole

Targeting 5-HT 1A Receptors to Correct Perineuronal Net and Social Behavioral Deficits in Fmr1 Knockout Mice, a Model of Fragile X Syndrome

The Need To Improve Reporting of the Pharmacological Action of New Molecules

Structure-Activity Relationship Study of Psychostimulant Synthetic Cathinones Reveals Nanomolar Antagonist Potency of α-Pyrrolidinohexiophenone at Human Muscarinic M 2 Receptors

Structure–Activity Relationship Study of Psychostimulant Synthetic Cathinones Reveals Nanomolar Antagonist Potency of α‑Pyrrolidinohexiophenone at Human Muscarinic M2 Receptors

Serotonergic Psychedelics: Experimental Approaches for Assessing Mechanisms of Action

Spontaneous seizures in adult Fmr1 knockout mice: FVB.129P2-Pde6b+Tyrc-chFmr1tm1Cgr/J

Spontaneous seizures in adult Fmr1 knockout mice: FVB.129P2-Pde6b+ Tyr Fmr1/J

Targeting 5‐HT1A Receptors to Correct Neuronal Hyperexcitability in Fmr1 Knockout Mice

Ligand-directed serotonin 5-HT2C receptor desensitization and sensitization

Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model

Effects of the second-generation "bath salt" cathinone alpha-pyrrolidinopropiophenone (α-PPP) on behavior and monoamine neurochemistry in male mice

Synthesis and Structure–Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5‑HT2 Receptor Agonist

Synthesis and Structure-Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT 2 Receptor Agonist

The Psychedelic N,N‑Dipropyltryptamine Prevents Seizures in a Mouse Model of Fragile X Syndrome via a Mechanism that Appears Independent of Serotonin and Sigma1 Receptors

Evaluation of lorcaserin as an anticonvulsant in juvenile Fmr1 knockout mice

Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HT1A and 5-HT7 G protein-coupled receptor affinity, 3D-QSAR and molecular modeling

M100907 and BD 1047 attenuate the acute toxic effects of methamphetamine

NeuroChat with Professor Clinton E. Canal

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