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Discovery of 2‑Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

Journal of medicinal chemistry, 2016-03, Vol.59 (5), p.2054-2066

2016

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Discovery of Tricyclic Indoles That Potently Inhibit Mcl‑1 Using Fragment-Based Methods and Structure-Based Design

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.3794-3805

2015

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High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

Analytical biochemistry, 2018-05, Vol.548 (C), p.44-52

2018

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Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia‑1 Inhibitors Using Structure-Based Design

Journal of medicinal chemistry, 2018-03, Vol.61 (6), p.2410-2421

2018

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Discovery and biological characterization of potent myeloid cell leukemia‐1 inhibitors

FEBS letters, 2017-01, Vol.591 (1), p.240-251

2017

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Discovery of a Potent Inhibitor of Replication Protein A Protein–Protein Interactions Using a Fragment-Linking Approach

Journal of medicinal chemistry, 2013-11, Vol.56 (22), p.9242-9250

2013

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A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand

Journal of biomolecular NMR, 2014-09, Vol.60 (1), p.11-14

2014

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Fully automated protein purification

Analytical biochemistry, 2009-10, Vol.393 (2), p.176-181

2009

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Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication ProteinA

ChemMedChem, 2016-04, Vol.11 (8), p.893

2016

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Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A

ChemMedChem, 2016-04, Vol.11 (8), p.893-899

2016

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Zirconium tungstate hydroxide hydrate revisited: Crystallization dependence on halide and hydronium ions

Journal of solid state chemistry, 2007-12, Vol.180 (12), p.3504-3509

2007

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Abstract 865: Small molecule-mediated modulation of Ras elicits inhibition of phospho ERK signaling through negative feedback on SOS1

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.865-865

2018

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High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

Analytical biochemistry, 2018-05, Vol.548 (C)

2018

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Abstract 3695: Discovery of probes to evaluate the disruption of the protein-protein interactions mediated by RPA70N

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.3695-3695

2015

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Abstract 4417: Targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.4417-4417

2014

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Discovery of 2‑Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

Discovery of Tricyclic Indoles That Potently Inhibit Mcl‑1 Using Fragment-Based Methods and Structure-Based Design

High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia‑1 Inhibitors Using Structure-Based Design

Discovery and biological characterization of potent myeloid cell leukemia‐1 inhibitors

Discovery of a Potent Inhibitor of Replication Protein A Protein–Protein Interactions Using a Fragment-Linking Approach

A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand

Fully automated protein purification

Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication ProteinA

Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A

Zirconium tungstate hydroxide hydrate revisited: Crystallization dependence on halide and hydronium ions

Abstract 865: Small molecule-mediated modulation of Ras elicits inhibition of phospho ERK signaling through negative feedback on SOS1

High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors

Abstract 3695: Discovery of probes to evaluate the disruption of the protein-protein interactions mediated by RPA70N

Abstract 4417: Targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

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