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Cross-Coupling and Related Reactions: Connecting Past Success to the Development of New Reactions for the Future

Organometallics, 2019-01, Vol.38 (1), p.3-35

2019

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Acridinium-Based Photocatalysts: A Sustainable Option in Photoredox Catalysis

Journal of organic chemistry, 2016-08, Vol.81 (16), p.7244-7249

2016

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Analysis of Benzenoid Substitution Patterns in Small Molecule Active Pharmaceutical Ingredients

Journal of medicinal chemistry, 2020-11, Vol.63 (22), p.13389-13396

2020

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Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules

Chemical communications (Cambridge, England), 2006-01 (12), p.1253-1264

2006

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Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

Science (American Association for the Advancement of Science), 2015-01, Vol.347 (6217), p.49-53

2015

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A multifunctional catalyst that stereoselectively assembles prodrugs

Science (American Association for the Advancement of Science), 2017-04, Vol.356 (6336), p.426-430

2017

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A short de novo synthesis of nucleoside analogs

Science (American Association for the Advancement of Science), 2020-08, Vol.369 (6504), p.725-730

2020

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Development of a Direct Photocatalytic C–H Fluorination for the Preparative Synthesis of Odanacatib

Organic letters, 2015-11, Vol.17 (21), p.5200-5203

2015

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A Solution to the 2-Pyridyl Organometallic Cross-Coupling Problem: Regioselective Catalytic Direct Arylation of Pyridine N-Oxides

Journal of the American Chemical Society, 2005-12, Vol.127 (51), p.18020-18021

2005

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Mechanistic Analysis of Azine N-Oxide Direct Arylation: Evidence for a Critical Role of Acetate in the Pd(OAc)2 Precatalyst

Journal of organic chemistry, 2010-12, Vol.75 (23), p.8180-8189

2010

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Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir

Chemical science (Cambridge), 2016-03, Vol.7 (3), p.2066-2073

2016

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Chemistry informer libraries: a chemoinformatics enabled approach to evaluate and advance synthetic methods

Chemical science (Cambridge), 2016-01, Vol.7 (4), p.2604-2613

2016

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Palladium-Catalyzed Direct Arylation of Azine and Azole N-Oxides: Reaction Development, Scope and Applications in Synthesis

Journal of the American Chemical Society, 2009-03, Vol.131 (9), p.3291-3306

2009

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P2Et Phosphazene: A Mild, Functional Group Tolerant Base for Soluble, Room Temperature Pd-Catalyzed C–N, C–O, and C–C Cross-Coupling Reactions

Organic letters, 2015-07, Vol.17 (13), p.3370-3373

2015

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In Vitro Characterization of MK-1439, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

Antimicrobial Agents and Chemotherapy, 2014-03, Vol.58 (3), p.1652-1663

2014

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Biaryl Synthesis via Direct Arylation: Establishment of an Efficient Catalyst for Intramolecular Processes

Journal of the American Chemical Society, 2004-08, Vol.126 (30), p.9186-9187

2004

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Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods

Chemical science (Cambridge), 2021-07, Vol.12 (26), p.931-936

2021

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A Robust Kilo-Scale Synthesis of Doravirine

Organic process research & development, 2016-08, Vol.20 (8), p.1476-1481

2016

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A recipe for cultural change in the pharmaceutical industry

Tetrahedron, 2022-12, Vol.129, p.133076, Article 133076

2022

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Applications of and alternatives to pi-electron-deficient azine organometallics in metal catalyzed cross-coupling reactions

Chemical Society reviews, 2007-07, Vol.36 (7), p.1058-1068

2007

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Cobalt-Catalyzed Enantioselective Hydrogenation of Minimally Functionalized Alkenes: Isotopic Labeling Provides Insight into the Origin of Stereoselectivity and Alkene Insertion Preferences

Journal of the American Chemical Society, 2016-03, Vol.138 (10), p.3314-3324

2016

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A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions

Chemical science (Cambridge), 2017-04, Vol.8 (4), p.2841-2851

2017

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Nickel-Catalyzed Asymmetric Alkene Hydrogenation of α,β-Unsaturated Esters: High-Throughput Experimentation-Enabled Reaction Discovery, Optimization, and Mechanistic Elucidation

Journal of the American Chemical Society, 2016-03, Vol.138 (10), p.3562-3569

2016

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The Roles of Organometallic Chemistry in Pharmaceutical Research and Development

Organometallics, 2019-01, Vol.38 (1), p.1-2

2019

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Palladium-Catalyzed Direct Arylation of Nitro-Substituted Aromatics with Aryl Halides

Organic letters, 2008-10, Vol.10 (20), p.4533-4536

2008

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Cross-Coupling and Related Reactions: Connecting Past Success to the Development of New Reactions for the Future

Acridinium-Based Photocatalysts: A Sustainable Option in Photoredox Catalysis

Analysis of Benzenoid Substitution Patterns in Small Molecule Active Pharmaceutical Ingredients

Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules

Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

A multifunctional catalyst that stereoselectively assembles prodrugs

A short de novo synthesis of nucleoside analogs

Development of a Direct Photocatalytic C–H Fluorination for the Preparative Synthesis of Odanacatib

A Solution to the 2-Pyridyl Organometallic Cross-Coupling Problem: Regioselective Catalytic Direct Arylation of Pyridine N-Oxides

Mechanistic Analysis of Azine N-Oxide Direct Arylation: Evidence for a Critical Role of Acetate in the Pd(OAc)2 Precatalyst

Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir

Chemistry informer libraries: a chemoinformatics enabled approach to evaluate and advance synthetic methods

Palladium-Catalyzed Direct Arylation of Azine and Azole N-Oxides: Reaction Development, Scope and Applications in Synthesis

P2Et Phosphazene: A Mild, Functional Group Tolerant Base for Soluble, Room Temperature Pd-Catalyzed C–N, C–O, and C–C Cross-Coupling Reactions

In Vitro Characterization of MK-1439, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

Biaryl Synthesis via Direct Arylation: Establishment of an Efficient Catalyst for Intramolecular Processes

Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods

A Robust Kilo-Scale Synthesis of Doravirine

A recipe for cultural change in the pharmaceutical industry

Applications of and alternatives to pi-electron-deficient azine organometallics in metal catalyzed cross-coupling reactions

Cobalt-Catalyzed Enantioselective Hydrogenation of Minimally Functionalized Alkenes: Isotopic Labeling Provides Insight into the Origin of Stereoselectivity and Alkene Insertion Preferences

A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions

Nickel-Catalyzed Asymmetric Alkene Hydrogenation of α,β-Unsaturated Esters: High-Throughput Experimentation-Enabled Reaction Discovery, Optimization, and Mechanistic Elucidation

The Roles of Organometallic Chemistry in Pharmaceutical Research and Development

Palladium-Catalyzed Direct Arylation of Nitro-Substituted Aromatics with Aryl Halides

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