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Design and characterization of an APC-specific serpin for the treatment of hemophilia

Blood, 2017-01, Vol.129 (1), p.105-113

2017

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Insights into vitamin K-dependent carboxylation: home field advantage

Haematologica (Roma), 2020-08, Vol.105 (8), p.1996-1998

2020

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Tissue factor pathway inhibitor-alpha inhibits prothrombinase during the initiation of blood coagulation

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17838-17843

2013

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Activated protein C has a regulatory role in factor VIII function

Blood, 2021-05, Vol.137 (18), p.2532-2543

2021

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An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics

Science translational medicine, 2020-10, Vol.12 (565)

2020

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A Bipartite Autoinhibitory Region within the B-domain Suppresses Function in Factor V

The Journal of biological chemistry, 2012-07, Vol.287 (31), p.26342-26351

2012

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Minimal modification in the factor VIII B-domain sequence ameliorates the murine hemophilia A phenotype

Blood, 2013-05, Vol.121 (21), p.4396-4403

2013

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Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis

Blood, 2013-10, Vol.122 (16), p.2777-2783

2013

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Blood coagulation factor X: molecular biology, inherited disease, and engineered therapeutics

Journal of thrombosis and thrombolysis, 2021-08, Vol.52 (2), p.383-390

Camire, Rodney M.

2021

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New insights into the spatiotemporal localization of prothrombinase in vivo

Blood, 2014-09, Vol.124 (11), p.1705-1714

2014

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Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (21), p.7416-7421

2008

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Regulation of factor V and factor V-short by TFPIα: Relationship between B-domain proteolysis and binding

The Journal of biological chemistry, 2021-01, Vol.296, p.100234-100234, Article 100234

2021

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Factor IXa variants resistant to plasma inhibitors enhance clot formation in vivo

Blood, 2023-04, Vol.141 (16), p.2022-2032

2023

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Regulation of factor V by the anticoagulant protease activated protein C: Influence of the B-domain and TFPIα

The Journal of biological chemistry, 2022-11, Vol.298 (11), p.102558-102558, Article 102558

2022

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The Conformational Switch from the Factor X Zymogen to Protease State Mediates Exosite Expression and Prothrombinase Assembly

The Journal of biological chemistry, 2008-07, Vol.283 (27), p.18627-18635

2008

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Parahemophilia: new insights into factor v deficiency

Seminars in thrombosis and hemostasis, 2013-09, Vol.39 (6), p.607-612

2013

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AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes

Molecular therapy. Methods & clinical development, 2015-01, Vol.2, p.15029-15029, Article 15029

2015

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Enhancing functional platelet release in vivo from in vitro–grown megakaryocytes using small molecule inhibitors

Blood advances, 2018-03, Vol.2 (6), p.597-606

2018

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Removal of B-domain Sequences from Factor V Rather than Specific Proteolysis Underlies the Mechanism by Which Cofactor Function Is Realized

The Journal of biological chemistry, 2004-05, Vol.279 (20), p.21643-21650

2004

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Recombinant canine B-domain–deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model

Blood, 2009-11, Vol.114 (20), p.4562-4565

2009

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Whole-exome sequencing in evaluation of patients with venous thromboembolism

Blood advances, 2017-07, Vol.1 (16), p.1224-1237

2017

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Bioengineering factor Xa to treat bleeding

Thrombosis research, 2016-05, Vol.141, p.S31-S33

Camire, Rodney M

2016

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Hemostatic agents of broad applicability produced by selective tuning of factor Xa zymogenicity

Blood, 2015-07, Vol.126 (1), p.94-102

2015

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Prothrombinase Assembly and S1 Site Occupation Restore the Catalytic Activity of FXa Impaired by Mutation at the Sodium-binding Site

The Journal of biological chemistry, 2002-10, Vol.277 (40), p.37863-37870

Camire, Rodney M.

2002

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Design and characterization of an APC-specific serpin for the treatment of hemophilia

Insights into vitamin K-dependent carboxylation: home field advantage

An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia

Tissue factor pathway inhibitor-alpha inhibits prothrombinase during the initiation of blood coagulation

Activated protein C has a regulatory role in factor VIII function

An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics

A Bipartite Autoinhibitory Region within the B-domain Suppresses Function in Factor V

Minimal modification in the factor VIII B-domain sequence ameliorates the murine hemophilia A phenotype

Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis

Blood coagulation factor X: molecular biology, inherited disease, and engineered therapeutics

New insights into the spatiotemporal localization of prothrombinase in vivo

Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13

Regulation of factor V and factor V-short by TFPIα: Relationship between B-domain proteolysis and binding

Factor IXa variants resistant to plasma inhibitors enhance clot formation in vivo

Regulation of factor V by the anticoagulant protease activated protein C: Influence of the B-domain and TFPIα

The Conformational Switch from the Factor X Zymogen to Protease State Mediates Exosite Expression and Prothrombinase Assembly

Parahemophilia: new insights into factor v deficiency

AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes

Enhancing functional platelet release in vivo from in vitro–grown megakaryocytes using small molecule inhibitors

Removal of B-domain Sequences from Factor V Rather than Specific Proteolysis Underlies the Mechanism by Which Cofactor Function Is Realized

Recombinant canine B-domain–deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model

Whole-exome sequencing in evaluation of patients with venous thromboembolism

Bioengineering factor Xa to treat bleeding

Hemostatic agents of broad applicability produced by selective tuning of factor Xa zymogenicity

Prothrombinase Assembly and S1 Site Occupation Restore the Catalytic Activity of FXa Impaired by Mutation at the Sodium-binding Site

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